Results 71 to 80 of about 12,113 (146)

Integrative Analysis Uncover the Effects and Multi‐Omics Features of Thigh Muscle Fat Infiltration

Aging Cell, Volume 25, Issue 9, September 2026.
Thigh muscle fat infiltration (TMFI), estimated from MRI, is associated with increased mortality and diseases affecting multiple organ systems and mediates the effects of lifestyle factors on health. Multi‐omics analyses delineate the genetic, cellular, transcriptional, proteomic, and metabolic architecture of TMFI.
Yiwei Zhang, Qin Dang, Xizeng Zong, Haowei Chen, Simin Wen, Siqi Xu, Kunyan Wang, Xiaoshuai Wang, Jianwei Zhu, Zhaohua Zhu, Changhai Ding, Guangfeng Ruan, Yan Zhang   +12 more
wiley   +1 more source

Conversion of lipid transfer inhibitor protein (apolipoprotein F) to its active form depends on LDL composition

Journal of Lipid Research, 2011
Lipid transfer inhibitor protein (LTIP) exists in both active and inactive forms. Incubation (37°C) of plasma causes LTIP to transfer from a 470 kDa inactive complex to LDL where it is active. Here, we investigate the mechanisms underlying this movement.
Richard E. Morton, Diane J. Greene
doaj   +1 more source

Angiopoietin‐like protein 3 complete and partial deficiency markedly accelerates apolipoprotein B48 and B100 metabolism in triglyceride‐rich lipoproteins in humans

Journal of Internal Medicine, Volume 300, Issue 3, Page 312-328, September 2026.
Abstract Background Angiopoietin‐like protein 3 (ANGPTL3) is a key circulating regulator of triglyceride metabolism and a promising pharmacological target. The physiological consequences of profound ANGPTL3 deficiency can be explored in individuals with inherited loss‐of‐function (LOF) variants, who show reduced lifetime risk of atherosclerotic ...
Marcello Arca, Elias Björnson, Laura D'Erasmo, Alessia Di Costanzo, Simone Bini, Ilenia Minicocci, Daniele Tramontano, Stella Covino, Giuseppe Ciarlo, Manuela Lombardi, Sanni Söderlund, Niina Matikainen, Linda Andersson, Martin Adiels, Marja‐Riitta Taskinen, Chris J. Packard, Jan Borén   +16 more
wiley   +1 more source

Autophagy in MASLD: A Metabolic and Precision Medicine Perspective

Liver International, Volume 46, Issue 9, September 2026.
ABSTRACT Metabolic dysfunction‐associated steatotic liver disease (MASLD) is the most common chronic liver condition worldwide and a major contributor to cirrhosis and hepatocellular carcinoma (HCC). While metabolic triggers such as obesity and insulin resistance are key drivers of MASLD, growing evidence has identified defects in intracellular quality
Alessandra Cazzaniga, Silvia Frigo, Alessandro Cherubini, Eniada Rrapaj, Luca Valenti   +4 more
wiley   +1 more source

Human liposarcoma cell line, SW872, secretes cholesteryl ester transfer protein in response to cholesterol

Journal of Lipid Research, 1996
Cholesteryl ester transfer protein (CETP) mediates the exchange of phospholipids and neutral lipids between the plasma lipoproteins, and plays an important role in high density lipoprotein (HDL) metabolism.
M A Richardson, D T Berg, P A Johnston, D McClure, B W Grinnell   +4 more
doaj   +1 more source

Cholesteryl ester transfer protein inhibition is associated with reduced risk of Sjögren's syndrome. [PDF]

Rheumatology (Oxford), 2023
Zhao SS, Dyball S.
europepmc   +1 more source

Plasma cholesteryl ester transfer protein

Journal of Lipid Research, 1993
AR Tall
doaj   +1 more source

Msp1 Polymorphism of Cholesteryl Ester Transfer Protein in Patients with Hypercholesterolemia

پزشکی بالینی ابن سینا, 2013
Introduction & Objective: It has been shown that there is a correlation between cholesterol con-centration and coronary heart disease (CHD). Cholesteryl ester transfer protein (CETP) plays a central role in lipoproteins metabolism and it has been ...
Taghi Hassanzadeh, Asgar Barkhordary, Masoud Saidijam, Amir Fattahi, Zeinab Latifi   +4 more
doaj  

Roles of peripheral lipoproteins and cholesteryl ester transfer protein in the vascular contributions to cognitive impairment and dementia. [PDF]

Mol Neurodegener, 2023
Poliakova T, Wellington CL.
europepmc   +1 more source

Anacetrapib: potential for the prevention and treatment of coronary heart disease

Research Reports in Clinical Cardiology, 2013
Dylan L Steen,1 Amit V Khera,2 Christopher P Cannon1 1TIMI Study Group, Cardiovascular Division, 2Department of Medicine, Brigham and Women’s Hospital, Boston, MA, USA Abstract: Despite major advances in cardiovascular care in recent decades ...
Steen DL, Khera AV, Cannon CP
doaj