Results 101 to 110 of about 5,014,718 (261)

The Mechanism Exploration of Traditional Chinese Medicine's “Different Treatments for Same Disease” Concept in Osteoporosis Therapy: A Serum Metabolomics Study

open access: yesJournal of Cellular and Molecular Medicine, Volume 29, Issue 13, July 2025.
ABSTRACT The “different treatments for same disease” is an important concept of traditional Chinese medicine (TCM) therapy. In TCM, osteoporosis (OP) treatment is aimed at invigorating blood, strengthening spleen, and tonifying kidneys, and their typical herbs are Angelica sinensis (Oliv.) Diels (Danggui, DG), Poria cocos (Schw.) Wolf (Fuling, FL), and
Jingyuan Wen   +13 more
wiley   +1 more source

HFD Exacerbates Hepatic Lipid Metabolism Disorders After Cholecystectomy by Regulating the Bile Acid and Neutrophil Recruitment

open access: yesLiver International, Volume 45, Issue 7, July 2025.
ABSTRACT Background and Aims Previous studies have suggested that cholecystectomy may lead to an elevated risk of metabolic dysfunction‐associated fatty liver disease (MAFLD). However, there is a dearth of knowledge concerning the precise effects and underlying mechanisms through which cholecystectomy influences hepatic lipid metabolism, necessitating ...
Yanting Xu   +8 more
wiley   +1 more source

The economy of the enterohepatic circulation of bile acids in the baboon. 2. Regulation of bile acid synthesis by enterohepatic circulation of bile acids.

open access: yesJournal of Lipid Research, 1984
Isotope dilution within bile acid pools and radiochemical assessment of cholesterol oxidation to bile acids were methods used to measure short-term feedback regulation of bile acid synthesis in baboons with controlled enterohepatic circulations ...
R N Redinger
doaj  

Analysis of the Electron Density of a Water Molecule Encapsulated by Two Cholic Acid Residues. [PDF]

open access: yesInt J Mol Sci, 2023
Vázquez-Tato MP   +4 more
europepmc   +1 more source

Bile acid formation in man: metabolism of 7α-hydroxy-4-cholesten-3-one in bile fistula patients

open access: yesJournal of Lipid Research, 1973
7α-Hydroxy-4-cholesten-3-one is thought to be an intermediate in human bile acid synthesis. This conclusion is based on in vivo experiments in animals and on in vitro studies in which homogenates of animal and human livers were used. To further establish
Russell F. Hanson   +2 more
doaj  

Bile acid-containing lipid nanoparticles enhance extrahepatic mRNA delivery

open access: yesTheranostics
Lipid nanoparticles (LNPs) have emerged as a viable, clinically-validated platform for the delivery of mRNA therapeutics. LNPs have been utilized as mRNA delivery systems for applications including vaccines, gene therapy, and cancer immunotherapy ...
Savan K. Patel   +9 more
semanticscholar   +1 more source

Comparison of the binding sites of GSH S-transferases of the Ya- and Yb-subunit classes: effect of glutathione on the binding of bile acids.

open access: yesJournal of Lipid Research, 1988
We have previously observed that the Ya subunit-containing glutathione (GSH) S-transferases from rat liver exhibit a common high affinity binding site for lithocholic acid, bilirubin, and sulfobromophthalein (BSP) (1984. J. Lipid Res.
H Takikawa, N Kaplowitz
doaj  

Evidence that cholic acid CoA ligase is located asymmetrically on the cytoplasmic surface of hepatic microsomal vesicles.

open access: yesJournal of Lipid Research, 1979
The cholic acid CoA ligase activity of rat liver was quantitatively inactivated by proteolysis with pronase, chymotrypsin, subtilisin, or proteinase K in intact microsomal vesicles.
M A Polokoff, R A Coleman, R M Bell
doaj  

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