Results 81 to 90 of about 2,533,937 (176)

Cholic acid-based delivery system for vaccine candidates against Group A Streptococcus

open access: yes, 2019
Peptide-based subunit vaccines require an immunostimulant (adjuvant) and/or delivery system to protect the antigenic peptide from degradation and induce the desired immunity.
Bartlett, Stacey   +13 more
core   +1 more source

Periodontitis and Inflammatory Bowel Diseases: Mechanistic Evidence

open access: yesJournal of Periodontal Research, EarlyView.
This review aims to provide a conceptual framework for understanding the mechanistic interplay between periodontitis and IBD, with a particular emphasis on the microbial and immunological crosstalk linking the oral cavity and the gastrointestinal tract.
Ana Paula V. Colombo   +3 more
wiley   +1 more source

Translating gut microbiome research into therapies for type 1 diabetes

open access: yesExperimental Physiology, EarlyView.
Abstract Type 1 diabetes (T1D) is characterised by the loss of functional pancreatic β‐cells, for which lifelong insulin therapy remains the standard of care. Given that the gut microbiome can influence host health and that shifts in gut microbial profiles have been observed in T1D, growing interest has emerged in the role of the gut microbiome in T1D,
Shanti P. Kok   +2 more
wiley   +1 more source

Cholic acid-modified polyethylenimine: in vitro and in vivo studies

open access: yes, 2018
Brahmanand Dube,1,2 Abhijeet Pandey,1 Ganesh Joshi,3 Rita Mulherkar,3 Krutika Sawant1 1Pharmacy Department, Faculty of Pharmacy, The Maharaja Sayajirao University of Baroda, Vadodara, 2Wockhardt Research Centre, Wockhardt Ltd, Aurangabad, India ...
Sawant K   +4 more
core  

Preparation of new molecularly imprinted nanosensor for cholic acid determination

open access: yes, 2012
WOS: 000301214700023Molecular imprinted polymers (MIPs) as a recognition element for sensors are increasingly of interest and MIP-nanoparticles have started to appear in the literature.
Say, Ridvan   +4 more
core   +1 more source

Comprehensive Evaluation of Gastrointestinal Factors Influencing the Stability and Function of mRNA‐Encapsulated Lipid Nanoparticles

open access: yesDrug Development Research, Volume 87, Issue 7, November 2026.
ABSTRACT Owing to the intrinsic instability of mRNA, its routes of administration are limited, and to date, only injectable delivery has been clinically applied. In contrast, oral administration exposes mRNA to a variety of substances in the gastrointestinal (GI) tract.
Toma Shinkai   +3 more
wiley   +1 more source

Effects of cholic acid on the metabolism of endogenous plasma triglyceride and on biliary lipid composition in hyperlipoproteinemia.

open access: yesJournal of Lipid Research, 1980
Plasma lipids, endogenous triglyceride kinetics, and biliary lipid composition were determined in 13 patients with primary hyperlipoproteinemia (HLP) before and during treatment with cholic acid (15 mg/kg body weight/day for 3 months).
B Angelin, B Leijd
doaj   +1 more source

Lachnospiraceae in the Food–Gut Axis: A Critical Review of Dietary Modulation, Immune Regulation, and Translational Barriers

open access: yesComprehensive Reviews in Food Science and Food Safety, Volume 25, Issue 6, November 2026.
ABSTRACT The interplay between diet, gut microbiota, and host immunity is central to food science. The Lachnospiraceae family ferments dietary fibers to produce short‐chain fatty acids (SCFAs), notably butyrate and propionate, with immunomodulatory potential. This critical review distinguishes established findings from hypotheses.
Ruijun Wang   +4 more
wiley   +1 more source

Changes in biliary and fecal bile acids in mice after treatments with diosgenin and beta-sitosterol.

open access: yesJournal of Lipid Research, 1984
Diosgenin and beta-sitosterol (1% in diet) were administered to CRJ:CD-1 male mice for 15 days, in order to examine the changes in bile acid metabolism.
K Uchida   +5 more
doaj   +1 more source

Mapping Mutations and Signaling Network Interactions to Guide Precision Therapy in Gallbladder Cancer

open access: yesCancer Reports, Volume 9, Issue 10, October 2026.
ABSTRACT Background Gallbladder cancer (GBC) is a biologically complex malignancy arising from the epithelial lining of the gallbladder, with adenocarcinoma constituting the major histological subtype. Early detection is challenging because of vague clinical manifestations and the organ's deep‐seated anatomical location, resulting in diagnosis at ...
Nisha Manav   +4 more
wiley   +1 more source

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