Results 61 to 70 of about 20,088 (221)

Phytochemicals in MASLD: A Focused Review of Gut Microbiome‐Linked Mechanisms

Phytotherapy Research, EarlyView.
ABSTRACT Metabolic dysfunction‐associated steatotic liver disease (MASLD) has emerged as a major global health burden, yet effective pharmacological options remain limited. Recent advances highlight the gut microbiome as a key modulator of liver metabolism, inflammation, and fibrosis, making it a promising therapeutic target.
Jeong In Seo, Su Min Kim, Hye Hyun Yoo
wiley   +1 more source

Solvent‐Induced Surface Morphology Probed by NP‐SIMS

Surface and Interface Analysis, EarlyView.
ABSTRACT Surface morphology, that is, roughness and molecular arrangement, is known to have an impact on secondary ion mass spectra. The present study examines this issue using nanoprojectile secondary ion mass spectrometry (NP‐SIMS). NP‐SIMS involves bombarding the analyte with individual nanoparticles resolved in space and time and recording the ...
Pierre Hirchenhahn, Stanislav Verkhoturov, Michael Eller, Wilson Serem, Yordanos Bisrat, Emile A. Schweikert   +5 more
wiley   +1 more source

Chemotactic responses to a mixture of cholic acid and lithocholic acid.

, 2018
Chemotactic migration of CsNEJs to a mixed solution of cholic acid and lithocholic acid was examined in 1 h. The mixed solution was made of 50 mM cholic acid and lithocholic acid at concentrations of 0.13–8 mM (A), or 1 mM lithocholic acid and cholic ...
Won Gi Yoo (193369), Shunyu Li (5807027), Jin-Ho Song (5807030), Sung-Jong Hong (215704), Tae Im Kim (193368)   +4 more
core   +1 more source

Periodontitis and Inflammatory Bowel Diseases: Mechanistic Evidence

Journal of Periodontal Research, EarlyView.
This review aims to provide a conceptual framework for understanding the mechanistic interplay between periodontitis and IBD, with a particular emphasis on the microbial and immunological crosstalk linking the oral cavity and the gastrointestinal tract.
Ana Paula V. Colombo, Adriana M. de Oliveira, Nobuhiko Kamada, Sho Kitamoto   +3 more
wiley   +1 more source

The economy of the enterohepatic circulation of bile acids in the baboon. 2. Regulation of bile acid synthesis by enterohepatic circulation of bile acids.

Journal of Lipid Research, 1984
Isotope dilution within bile acid pools and radiochemical assessment of cholesterol oxidation to bile acids were methods used to measure short-term feedback regulation of bile acid synthesis in baboons with controlled enterohepatic circulations ...
R N Redinger
doaj   +1 more source

Intratumoral Microbiota in Tumor: Current Understandings and Future Perspectives

MedComm, Volume 7, Issue 7, July 2026.
Intratumoral bacteria are emerging as active regulators of cancer evolution rather than bystanders. This review outlines how tumor‐resident microbes drive tumor initiation and growth by inducing genomic instability, epigenetic reprogramming, oncogenic signaling, and chronic inflammation, while promoting metastatic spread via invasion, angiogenesis ...
Jiawei Chen, Yupan Bai, Lu Shen, Jiacheng Ying, Jie Xu, Jiayin Tang, Yujie Bao   +6 more
wiley   +1 more source

Bile acid formation in man: metabolism of 7α-hydroxy-4-cholesten-3-one in bile fistula patients

Journal of Lipid Research, 1973
7α-Hydroxy-4-cholesten-3-one is thought to be an intermediate in human bile acid synthesis. This conclusion is based on in vivo experiments in animals and on in vitro studies in which homogenates of animal and human livers were used. To further establish
Russell F. Hanson, Peter D. Klein, Gale C. Williams   +2 more
doaj   +1 more source

Urologic Bacteriome: The Hero or the Villain in Prostate Cancer Onset, Progression, and Treatment?

Medicinal Research Reviews, Volume 46, Issue 4, Page 1111-1151, July 2026.
ABSTRACT Prostate cancer (PCa) is the second most frequently diagnosed cancer in men worldwide and the fifth leading cause of cancer‐related mortality, presenting urgent unmet clinical needs in diagnosis and treatment. The recognition of the microbiome as a key factor in human health has prompted numerous studies, revealing an exciting new approach to ...
Lara R. S. Fonseca, Mariana Feijó, Cátia V. Vaz, Bruno J. Pereira, Sandra Laurentino, Ana Palmeira‐de‐Oliveira, Sílvia Socorro   +6 more
wiley   +1 more source

Mechanism of intestinal 7 alpha-dehydroxylation of cholic acid: evidence that allo-deoxycholic acid is an inducible side-product.

Journal of Lipid Research, 1991
We previously reported that the 7 alpha-dehydroxylation of cholic acid appears to be carried out by a multi-step pathway in intestinal anaerobic bacteria both in vitro and in vivo.
PB Hylemon, PD Melone, CV Franklund, E Lund, I Björkhem   +4 more
doaj   +1 more source

Bile acids drive chemotaxis of Clonorchis sinensis juveniles to the bile duct. [PDF]

PLoS Neglected Tropical Diseases, 2018
Clonorchiasis is a neglected tropical disease caused by Chinese liver fluke, Clonorchis sinensis infection. C. sinensis is a biological carcinogen causing cholangiocarcinoma in humans. In the mammalian host, C.
Shunyu Li, Won Gi Yoo, Jin-Ho Song, Tae Im Kim, Sung-Jong Hong   +4 more
doaj   +1 more source