Results 51 to 60 of about 20,088 (221)

Reprogramming tumor immune microenvironment by ultrasound‐responsive nanoplatforms for enhanced cancer immunotherapy

open access: yesBMEMat, EarlyView.
Ultrasound‐responsive nanoplatforms reprogram the tumor immune microenvironment by targeting tumor cells, immune cells, and non‐immune stromal cells to enhance the efficacy of cancer immunotherapy. Abstract Cancer immunotherapy represents a significant advancement in cancer treatment by enhancing the specific recognition and elimination of cancer cells.
Shilong Zhao   +4 more
wiley   +1 more source

Chemical Metabolomics: Chemical Biology Tools for Advanced Metabolism Investigations

open access: yesAngewandte Chemie, Volume 138, Issue 23, 1 June 2026.
The human metabolism has been investigated for several millennia. The metabolome is known for a high complexity due to a large number of different metabolites that are present at different concentrations. Metabolomics has been developed as a field to investigate the entire human metabolome and to elucidate disease development mechanisms.
Alejandro Torregrosa‐Chinillach   +4 more
wiley   +2 more sources

Hepatic 3-hydroxy-3-methylglutaryl coenzyme A reductase activity and biliary lipid composition in man: relation to cholesterol gallstone disease and effects of cholic acid and chenodeoxycholic acid treatment

open access: yesJournal of Lipid Research, 1981
The present work was undertaken in order to study whether or not there is a relation between hepatic HMG CoA reductase, hepatic cholesterol concentration, and biliary lipid composition.
J Ahlberg, B Angelin, K Einarsson
doaj   +1 more source

Multi‐omics biomarkers for intestinal infection and inflammation in inflammatory bowel disease: Current evidence, translational challenges, and diagnostic opportunities

open access: yesInterdisciplinary Medicine, EarlyView.
Prospective multi‐site cohorts, multi‐omics profiling, and computational analysis may help identify biomarker patterns across clinical settings in IBD and superimposed infections. With further mechanistic and clinical validation, these signals could support the development of practical multi‐analyte tools for more precise diagnosis and management ...
Ziyu Yang   +7 more
wiley   +1 more source

Reactivation of CsNEJs by additional cholic acid.

open access: yes, 2018
Cholic acid (50 mM; arrow) was applied at 0, 10, and 20 min as indicated with three downward arrows, and migration distance of CsNEJs was measured every min.
Won Gi Yoo (193369)   +4 more
core   +1 more source

Safety and Effectiveness of Compounded Galenic Cholic Acid for Bile Acid Synthesis Disorder: A Case Report

open access: yes, 2022
Background: Bile acid synthesis disorders are rare congenital diseases that can lead to cirrhosis and end-stage liver disease if left untreated. Cholic acid administration is the only treatment that can prevent patients from fatal outcomes. Since 2013 in
Burlo, Francesca   +13 more
core   +1 more source

The minor bile acids of the toad, Bufo vulgaris formosus.

open access: yesJournal of Lipid Research, 1983
Bile from the toad, Bufo vulgaris formosus, was found to contain a number of minor bile acids along with two major bile acids, 3 alpha, 7 alpha, 12 alpha-trihydroxy-5 beta-cholest-22-ene-24-carboxylic acid and 3 alpha, 7 alpha, 12 alpha-trihydroxy-5 beta-
M Une, T Kuramoto, T Hoshita
doaj   +1 more source

Metabolic Dysfunction‐Associated Steatotic Liver Disease and Obesity: Pathogenesis, Diagnostics, Risk Stratification, and Therapeutic Approach

open access: yesThe Kaohsiung Journal of Medical Sciences, EarlyView.
ABSTRACT Metabolic dysfunction‐associated steatotic liver disease (MASLD) has emerged as the most prevalent chronic liver disease worldwide, closely linked to the global rising incidence of obesity and metabolic syndrome. This review synthesizes current evidence on the pathogenesis, gut–liver axis, and multidisciplinary management of MASLD within the ...
Beom Kyung Kim
wiley   +1 more source

Cholic acid/deoxycholic acid-related molecules correlated with parasite burden.

open access: yes, 2018
Cholic acid/deoxycholic acid-related molecules correlated with parasite burden.
Anupriya Tripathi (4228504)   +5 more
core   +1 more source

Bile acids in the rat: studies in experimental occlusion of the bile duct

open access: yesJournal of Lipid Research, 1966
Bile acids in the plasma, urine, and small intestine of adult male rats with occluded bile ducts have been studied using a method of high specificity for their determination. After bile duct ligation cholic acid rapidly accumulates in the plasma for 8 hr,
G.S. Boyd, M.A. Eastwood, N. Maclean
doaj   +1 more source

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