Results 31 to 40 of about 20,088 (221)

Physiological characteristics of allo-cholic acid [PDF]

open access: yesJournal of Lipid Research, 2003
The physiological characterstics of allo-cholic acid (ACA), a typically fetal bile acid that reappears during liver regeneration and carcinogenesis were investigated. [(14)C] Tauro-ACA (TACA) uptake by Chinese hamster ovary cells expressing rat organic anion transporter polypeptide (Oatp)1 or sodium-taurocholate cotransporter polypeptide (Ntcp) was ...
Mendoza, Maria E.   +7 more
openaire   +5 more sources

Oxidoreduction of different hydroxyl groups in bile acids during their enterohepatic circulation in man.

open access: yesJournal of Lipid Research, 1986
The extent of oxidoreduction of the 3 alpha-, 7 alpha- and 12 alpha-hydroxyl groups in bile acids during the enterohepatic circulation in man was studied with the use of [3 beta-3H]-labeled deoxycholic acid and cholic acid, [7 beta-3H]-labeled cholic ...
I Björkhem   +3 more
doaj   +1 more source

Cholic acid–quinoxaline (2/1) [PDF]

open access: yesActa Crystallographica Section E Structure Reports Online, 2008
In the title inclusion compound, 2C(24)H(40)O(5)·C(8)H(6)N(2), the unit cell contains two mol-ecules of cholic acid (3α,7α,12α-trihydr-oxy-5β-cholan-24-oic acid) and one mol-ecule of quinoxaline which implies disorder of the quinoxaline in the space group P2(1).
Wicher, Barbara, Gdaniec, Maria
openaire   +2 more sources

An in vivo evaluation of the quantitative significance of several potential pathways to cholic and chenodeoxycholic acids from cholesterol in man

open access: yesJournal of Lipid Research, 1980
The present study was designed to obtain more definitive information in man on the metabolic pathways to chenodeoxycholic acid and to cholic acid via a pathway not involving an initial 7 alpha-hydroxylation of cholesterol. Four bile fistula patients were
L Swell   +5 more
doaj   +1 more source

Human hepatoblastoma cells (HepG2) and rat hepatoma cells are defective in important enzyme activities in the oxidation of the C27 steroid side chain in bile acid formation

open access: yesJournal of Lipid Research, 1993
We have examined the ability of HepG2 human hepatoblastoma cells and 7800 C1 Morris rat hepatoma cells to convert 3 alpha, 7 alpha, 12 alpha-trihydroxy-5 beta-cholestanoic acid (THCA) and 3 alpha, 7 alpha-dihydroxy-5 beta-cholestanoic acid (DHCA) to ...
Ann-Kristin Östlund Farrants   +2 more
doaj   +1 more source

Validation of [22,23-3H]cholic acid as a stable tracer through conversion to deoxycholic acid in human subjects

open access: yesJournal of Lipid Research, 1996
Bile acids labeled with 3H on the sterol nucleus lose a substantial fraction of label during enterohepatic cycling and conversion to secondary bile acids. We tested the isotopic stability of a side-chain 3H label, [22,23-3H]cholic acid in humans.
W C Duane   +3 more
doaj   +1 more source

Competitive inhibition of side chain oxidation of 3 alpha, 7 alpha-dihydroxy-5 beta-cholestan-26-oic acid by 3 alpha, 7 alpha, 12 alpha-trihydroxy-5 beta-cholestan-26-oic acid in the hamster.

open access: yesJournal of Lipid Research, 1980
3 alpha,7 alpha-dihydroxy-5 beta-cholestan-26-oic acid (DHCA) and 3 alpha,7 alpha,12 alpha-trihydroxy-5 beta-cholestan-26-oic acid (THCA) are metabolized into chenodeoxycholic acid and cholic acid, respectively, through oxidation and cleavage of the ...
O W Cass, G C Williams, R F Hanson
doaj   +1 more source

Influence of Bile Acids in Hydrogel Pharmaceutical Formulations on Dissolution Rate and Permeation of Clindamycin Hydrochloride

open access: yesGels, 2022
Clindamycin hydrochloride is a widely used antibiotic for topical use, but its main disadvantage is poor skin penetration. Therefore, new approaches in the development of clindamycin topical formulations are of great importance.
Nebojša Pavlović   +6 more
doaj   +1 more source

The structures of baicalin, jasminoidin and cholic acid. A. baicalin; B. jasminoidin; C. cholic acid.

open access: yes, 2013
The structures of baicalin, jasminoidin and cholic acid. A. baicalin; B. jasminoidin; C. cholic acid.
Zhanjun Zhang (379921)   +6 more
core   +1 more source

Hydrophobic Tetramer Structures of Cholic Acid

open access: yes, 2016
Cholic acid (CA) is a primary bile acid which possesses facial amphiphilicity and self-assembly ability. CA is slightly soluble in water, which makes it impossible to form the self-assembled structures spontaneously in aqueous solutions.
Yueqin Duan (1864408)   +3 more
core   +2 more sources

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