Cholic Acid-Based Antimicrobial Peptide Mimics as Antibacterial Agents. [PDF]
Int J Mol Sci, 2022 There is a significant and urgent need for the development of novel antibacterial agents to tackle the increasing incidence of antibiotic resistance. Cholic acid-based small molecular antimicrobial peptide mimics are reported as potential new leads to ...
Wu J +8 more
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Development of a highly sensitive MIP based-QCM nanosensor for selective determination of cholic acid level in body fluids [PDF]
Materials Science and Engineering C, 2014 Determination of cholic acid is very important and necessary in body fluids due to its both pharmaceutical and clinical significance. In this study, a quartz crystal microbalance (QCM) nanosensor, which is imprinted cholic acid, has been developed for ...
Ridvan Say +2 more
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New cholic acid derivatives: Biocatalytic synthesis and molecular docking study [PDF]
Steroids, 2016 A series of cholic acid derivatives was synthesized by enzyme catalysis. Eleven acetyl and ester derivatives of cholic acid, eight of them new compounds, were obtained through regioselective lipase-catalyzed reactions in very good to excellent yield. The
Alicia Baldessari
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Synthesis of Both Ionic Species of Ammonium Dithiocarbamate Derived Cholic Acid Moieties
Molecules, 2011 The reaction of 3-aminopropylamide of cholic acid with CS2 produced a bile acid derivative of dithiocarbamic acid which further formed an ammonium salt with another molecule of 3-aminopropylamide of cholic acid.
Erkki Kolehmainen, Juha Koivukorpi
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Journal of Lipid Research, 1987 The effect of dietary 7 beta-methyl-cholic acid [0.075% in rodent chow (6.4 mg/animal per day)] on cholesterol and bile acid metabolism was studied and compared with that of cholic acid in the hamster.
S Kuroki +4 more
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Colon tumor promotion, is it a selection process? Effects of cholate, phytate, and food restriction in rats on proliferation and apoptosis in normal and aberrant crypts [PDF]
, 1997 Promotion would suppose the selection of initiated cells. We tested the selection of aberrant crypt cells by cholic acid, a colon cancer promoter, and the effect of protectors, phytate and food restriction.
Peiffer, Ginette +5 more
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Journal of Lipid Research, 1977 The formation of cholic acid from 3α,7α,12α-trihydroxy-5β-cholestan-26-oic acid (THCA) was studied in two normal subjects. [3H]THCA and [14C]cholic acid were administered intravenously by simultaneous injection and the specific activities (percent ...
R F Hanson, G C Williams
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Mutations in SRD5B1 (AKR1D1), the gene encoding Delta(4)-3-oxosteroid 5 beta-reductase, in hepatitis and liver failure in infancy [PDF]
, 2003 Background: A substantial group of patients with cholestatic liver disease in infancy excrete, as the major urinary bile acids, the glycine and taurine conjugates of 7alpha-hydroxy-3-oxo-4-cholenoic acid and 7alpha, 12alpha-dihydroxy-3- oxo-4-cholenoic ...
Duran, M. +17 more
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Effects of fasting on bile acid metabolism and biliary lipid composition in man
Journal of Lipid Research, 1976 The effects of a four to six day fast on gallbladder bile lipid composition, bile acid pool size, bile acid composition, and cholic acid metabolism have been determined in normal human subjects.
W C Duane, R L Ginsberg, L J Bennion
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Journal of Lipid Research, 1989 12 alpha-Hydroxy-3-oxo-4-cholenoic acid coupled to an adenosine nucleotide has been shown to be a metabolite of cholic acid in the intestinal anaerobic bacteria, Eubacterium species VPI 12708 (1987. J. Biol. Chem.
I Björkhem +3 more
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