Results 11 to 20 of about 20,088 (221)

Synthesis of Both Ionic Species of Ammonium Dithiocarbamate Derived Cholic Acid Moieties

Molecules, 2011
The reaction of 3-aminopropylamide of cholic acid with CS2 produced a bile acid derivative of dithiocarbamic acid which further formed an ammonium salt with another molecule of 3-aminopropylamide of cholic acid.
Erkki Kolehmainen, Juha Koivukorpi
doaj   +2 more sources

Structure and Dynamics of Cholic Acid and Dodecylphosphocholine−Cholic Acid Aggregates [PDF]

Langmuir, 2010
Bile acids are powerful detergents that emulsify and solubilize lipids, vitamins, cholesterol and other molecules in the biliary tract and intestines. It has long been known that bile acids form soluble mixed micelles with lipids. However, the detailed thermodynamic and structural properties of these micelles are not fully understood.
Abdallah, Sayyed-Ahmad, Lenard M, Lichtenberger, Alemayehu A, Gorfe   +2 more
openaire   +2 more sources

Serum bile acids as a prognostic biomarker in biliary atresia following Kasai portoenterostomy

Hepatology, EarlyView., 2022
Serum bile acid levels predict outcomes in patients with biliary atresia who achieve normalized bilirubin levels after Kasai portoenterostomy. Abstract Background and Aims In biliary atresia, serum bilirubin is commonly used to predict outcomes after Kasai portoenterostomy (KP).
Sanjiv Harpavat, Kieran Hawthorne, Kenneth D. R. Setchell, Monica Narvaez Rivas, Lisa Henn, Charlotte A. Beil, Saul J. Karpen, Vicky L. Ng, Estella M. Alonso, Jorge A. Bezerra, Stephen L. Guthery, Simon Horslen, Kathy M. Loomes, Patrick McKiernan, John C. Magee, Robert M. Merion, Jean P. Molleston, Philip Rosenthal, Richard J. Thompson, Kasper S. Wang, Ronald J. Sokol, Benjamin L. Shneider, for Childhood Liver Disease Research Network (ChiLDReN)   +22 more
wiley   +1 more source

UPLC-QqQ-MS/MS-based Quantitative Analysis on Bile Acid in Hyperthyroidism Rats to Explore the Effects of Ginseng Herbs [PDF]

Zhipu Xuebao, 2023
A method of ultra-performance liquid chromatography-triple quadrupole tandem mass spectrometry (UPLC-QqQ-MS/MS) was developed to determine the contents of deoxycholic acid, chenodeoxycholic acid, hyodeoxycholic acid, cholic acid, glycinecholic acid ...
LIU Lin-lin, JIN Mo-zhu, DOU De-qiang
doaj   +1 more source

Facially Amphiphilic Cholic Acid-Lysine Conjugates as Promising Antimicrobials. [PDF]

ACS Omega, 2020
The emergence of multidrug-resistant microbes is a significant health concern posing a constant need for new antimicrobials. Membrane-targeting antibiotics are promising candidates with reduced ability of microbes to develop resistance.
Singla P, Kaur M, Kumari A, Kumari L, Pawar SV, Singh R, Salunke DB.   +6 more
europepmc   +2 more sources

7-Methyl bile acids: 7 beta-methyl-cholic acid inhibits bacterial 7-dehydroxylation of cholic acid and chenodeoxycholic acid in the hamster.

Journal of Lipid Research, 1987
The effect of dietary 7 beta-methyl-cholic acid [0.075% in rodent chow (6.4 mg/animal per day)] on cholesterol and bile acid metabolism was studied and compared with that of cholic acid in the hamster.
S Kuroki, E H Mosbach, B I Cohen, R J Stenger, C K McSherry   +4 more
doaj   +1 more source

Colon tumor promotion, is it a selection process? Effects of cholate, phytate, and food restriction in rats on proliferation and apoptosis in normal and aberrant crypts [PDF]

, 1997
Promotion would suppose the selection of initiated cells. We tested the selection of aberrant crypt cells by cholic acid, a colon cancer promoter, and the effect of protectors, phytate and food restriction.
Peiffer, Ginette, Denis E. Corpet, Sylviane Taché, Taché, Sylviane, Ginette Peiffer, Corpet, Denis E.   +5 more
core   +1 more source

Metabolism of 3α, 7α, 12α-trihydroxy-5β-cholestan-26-oic acid in normal subjects with an intact enterohepatic circulation

Journal of Lipid Research, 1977
The formation of cholic acid from 3α,7α,12α-trihydroxy-5β-cholestan-26-oic acid (THCA) was studied in two normal subjects. [3H]THCA and [14C]cholic acid were administered intravenously by simultaneous injection and the specific activities (percent ...
R F Hanson, G C Williams
doaj   +1 more source

Effects of fasting on bile acid metabolism and biliary lipid composition in man

Journal of Lipid Research, 1976
The effects of a four to six day fast on gallbladder bile lipid composition, bile acid pool size, bile acid composition, and cholic acid metabolism have been determined in normal human subjects.
W C Duane, R L Ginsberg, L J Bennion
doaj   +1 more source

Mutations in SRD5B1 (AKR1D1), the gene encoding Delta(4)-3-oxosteroid 5 beta-reductase, in hepatitis and liver failure in infancy [PDF]

, 2003
Background: A substantial group of patients with cholestatic liver disease in infancy excrete, as the major urinary bile acids, the glycine and taurine conjugates of 7alpha-hydroxy-3-oxo-4-cholenoic acid and 7alpha, 12alpha-dihydroxy-3- oxo-4-cholenoic ...
Duran, M., Scambler, PJ, Custard, E. J., Bouquet, J, Lemonde, H. A., Clayton, P. T., Duran, M, Overmars, H, Bouquet, J., Scambler, P.J., Lemonde, H., Clayton, P.T., Custard, EJ, Scambler, P. J., Clayton, PT, Lemonde, HA, Custard, E.J., Overmars, H.   +17 more
core   +1 more source