Results 51 to 60 of about 5,014,718 (261)

Bile acids drive chemotaxis of Clonorchis sinensis juveniles to the bile duct. [PDF]

open access: yesPLoS Neglected Tropical Diseases, 2018
Clonorchiasis is a neglected tropical disease caused by Chinese liver fluke, Clonorchis sinensis infection. C. sinensis is a biological carcinogen causing cholangiocarcinoma in humans. In the mammalian host, C.
Shunyu Li   +4 more
doaj   +1 more source

Paclitaxel-loaded nanoparticles of star-shaped cholic acid-core PLA-TPGS copolymer for breast cancer treatment

open access: yesNanoscale Research Letters, 2013
A system of novel nanoparticles of star-shaped cholic acid-core polylactide-d-α-tocopheryl polyethylene glycol 1000 succinate (CA-PLA-TPGS) block copolymer was developed for paclitaxel delivery for breast cancer treatment, which demonstrated superior in ...
Xiaolong Tang   +6 more
semanticscholar   +1 more source

Copolymerization of Hydrophilic and Hydrophobic Monomers in Water Assisted by Cyclodextrins

open access: yesNano Select, EarlyView.
Make it soluble! The formation of inclusion complex between cyclodextrins and a hydrophobic monomer derived from cholic acid improves its solubility in water and allows a successful copolymerization with acrylamide in water. The resulting polymer shows a UCST behavior in water.
Alexy Sanseigne   +3 more
wiley   +1 more source

A new method for the measurement of bile acid turnover and pool size by a double label, single intubation technique

open access: yesJournal of Lipid Research, 1981
A new method is described for measuring the cholic acid turnover and pool size by a single duodenal intubation technique. The method is based on determination in a single bile sample of the ratio of the specific activities of [14C]cholic acid and [3H ...
G Vantrappen, P Rutgeerts, Y Ghoos
doaj  

An Up‐to‐Date Review of Traditional Chinese Medicine in the Treatment of Atherosclerosis: Components, Mechanisms, and Therapeutic Potentials

open access: yesPhytotherapy Research, EarlyView.
Traditional Chinese medicine in atherosclerosis: multi‐target modulation of pathogenesis. ABSTRACT Atherosclerosis is a chronic inflammatory disease and a major global health concern. In recent years, traditional Chinese medicines (TCMs) have demonstrated multi‐target therapeutic potential against atherosclerosis by modulating inflammatory responses ...
Dilaram Nijat   +5 more
wiley   +1 more source

Metabolism of 5 beta-cholestane-3 alpha, 7 alpha, 12 alpha, 26-tetrol and 5 beta-cholestane-3 alpha, 7 alpha, 12 alpha, 25-tetrol into cholic acid in normal human subjects.

open access: yesJournal of Lipid Research, 1979
Side chain oxidation and cleavage of precursors in cholic acid synthesis is thought to involve initial hydroxylation at either position 25 or 26 of the side chain. Therefore, the conversion of 5 beta-cholestane-3 alpha, 7 alpha, 12 alpha, 26-tetrol and 5
R F Hanson, A B Staples, G C Williams
doaj  

Cholic Acid in Guinea Pig Bile.

open access: yesExperimental Biology and Medicine, 1960
SummaryCholic (3α, 7α, 12α-trihydroxycholanic) acid has been isolated from the guinea pig bile obtained from gall bladders as well as by biliary fistulae. However, this bile acid was found only in the bile of adult and not of immature guinea pigs. The other 2 bile acids isolated, chenodeoxycholic (3α, 7α-dihydroxycholanic) and 7-ketolithocholic (3α ...
Ludvik Peric-Golia, Russell S. Jones
openaire   +3 more sources

Lytic Transglycosylase Deficiency Increases Susceptibility to β‐lactam Antibiotics But Reduces Susceptibility to Vancomycin in Escherichia coli

open access: yesMicrobiology and Immunology, EarlyView.
ABSTRACT In Staphylococcus aureus, a gram‐positive pathogen, vancomycin‐resistant strains become susceptible to β‐lactam antibiotics, referred to as the “seesaw effect.” However, in gram‐negative bacteria, the phenomenon is less clear. Here, we analyzed the gene‐knockout effects of eight lytic transglycosylases (slt, mltA, mltB, mltC, mltD, mltE, mltF,
Takahiko Kimura   +4 more
wiley   +1 more source

Synthesis via RAFT polymerization of thermo- and pH-responsive random copolymers containing cholic acid moieties and their self-assembly in water

open access: yes, 2014
Here we report the design and synthesis of polymers containing cholic acid pendant groups, a major bile acid synthesized in the liver from cholesterol.
Sunirmal Pal, Saswati Roy, Priyadarsi De
semanticscholar   +1 more source

Gut Microbiota Regulate Lipid Metabolism via the Bile Acid Pathway: Resistance to Hypoxia in Gansu Zokor (Eospalax cansus)

open access: yesIntegrative Zoology, EarlyView.
The gut microbiota regulates lipid metabolism of Gansu zokor (Eospalax cansus) through the bile acid pathway in hypoxic environments, reflecting the unique survival strategy of subterranean rodents to maintain lipid metabolism homeostasis and flexible energy metabolism in hypoxic environments.
Maohong Yang   +5 more
wiley   +1 more source

Home - About - Disclaimer - Privacy