Results 11 to 20 of about 15,894 (230)

Structure and Dynamics of Cholic Acid and Dodecylphosphocholine−Cholic Acid Aggregates [PDF]

Langmuir, 2010
Bile acids are powerful detergents that emulsify and solubilize lipids, vitamins, cholesterol and other molecules in the biliary tract and intestines. It has long been known that bile acids form soluble mixed micelles with lipids. However, the detailed thermodynamic and structural properties of these micelles are not fully understood.
Abdallah, Sayyed-Ahmad, Lenard M, Lichtenberger, Alemayehu A, Gorfe   +2 more
openaire   +2 more sources

Serum bile acids as a prognostic biomarker in biliary atresia following Kasai portoenterostomy

Hepatology, EarlyView., 2022
Serum bile acid levels predict outcomes in patients with biliary atresia who achieve normalized bilirubin levels after Kasai portoenterostomy. Abstract Background and Aims In biliary atresia, serum bilirubin is commonly used to predict outcomes after Kasai portoenterostomy (KP).
Sanjiv Harpavat, Kieran Hawthorne, Kenneth D. R. Setchell, Monica Narvaez Rivas, Lisa Henn, Charlotte A. Beil, Saul J. Karpen, Vicky L. Ng, Estella M. Alonso, Jorge A. Bezerra, Stephen L. Guthery, Simon Horslen, Kathy M. Loomes, Patrick McKiernan, John C. Magee, Robert M. Merion, Jean P. Molleston, Philip Rosenthal, Richard J. Thompson, Kasper S. Wang, Ronald J. Sokol, Benjamin L. Shneider, for Childhood Liver Disease Research Network (ChiLDReN)   +22 more
wiley   +1 more source

Mutations in SRD5B1 (AKR1D1), the gene encoding Delta(4)-3-oxosteroid 5 beta-reductase, in hepatitis and liver failure in infancy [PDF]

, 2003
Background: A substantial group of patients with cholestatic liver disease in infancy excrete, as the major urinary bile acids, the glycine and taurine conjugates of 7alpha-hydroxy-3-oxo-4-cholenoic acid and 7alpha, 12alpha-dihydroxy-3- oxo-4-cholenoic ...
Duran, M., Scambler, PJ, Custard, E. J., Bouquet, J, Lemonde, H. A., Clayton, P. T., Duran, M, Overmars, H, Bouquet, J., Scambler, P.J., Lemonde, H., Clayton, P.T., Custard, EJ, Scambler, P. J., Clayton, PT, Lemonde, HA, Custard, E.J., Overmars, H.   +17 more
core   +1 more source

7-Methyl bile acids: 7 beta-methyl-cholic acid inhibits bacterial 7-dehydroxylation of cholic acid and chenodeoxycholic acid in the hamster.

Journal of Lipid Research, 1987
The effect of dietary 7 beta-methyl-cholic acid [0.075% in rodent chow (6.4 mg/animal per day)] on cholesterol and bile acid metabolism was studied and compared with that of cholic acid in the hamster.
S Kuroki, E H Mosbach, B I Cohen, R J Stenger, C K McSherry   +4 more
doaj   +1 more source

Colon tumor promotion, is it a selection process? Effects of cholate, phytate, and food restriction in rats on proliferation and apoptosis in normal and aberrant crypts [PDF]

, 1997
Promotion would suppose the selection of initiated cells. We tested the selection of aberrant crypt cells by cholic acid, a colon cancer promoter, and the effect of protectors, phytate and food restriction.
Peiffer, Ginette, Denis E. Corpet, Sylviane Taché, Taché, Sylviane, Ginette Peiffer, Corpet, Denis E.   +5 more
core   +1 more source

Validation of [22,23-3H]cholic acid as a stable tracer through conversion to deoxycholic acid in human subjects

Journal of Lipid Research, 1996
Bile acids labeled with 3H on the sterol nucleus lose a substantial fraction of label during enterohepatic cycling and conversion to secondary bile acids. We tested the isotopic stability of a side-chain 3H label, [22,23-3H]cholic acid in humans.
W C Duane, C D Schteingart, H T Ton-Nu, A F Hofmann   +3 more
doaj   +1 more source

Bile acids in the rat: studies in experimental occlusion of the bile duct

Journal of Lipid Research, 1966
Bile acids in the plasma, urine, and small intestine of adult male rats with occluded bile ducts have been studied using a method of high specificity for their determination. After bile duct ligation cholic acid rapidly accumulates in the plasma for 8 hr,
G.S. Boyd, M.A. Eastwood, N. Maclean
doaj   +1 more source

An in vivo evaluation of the quantitative significance of several potential pathways to cholic and chenodeoxycholic acids from cholesterol in man

Journal of Lipid Research, 1980
The present study was designed to obtain more definitive information in man on the metabolic pathways to chenodeoxycholic acid and to cholic acid via a pathway not involving an initial 7 alpha-hydroxylation of cholesterol. Four bile fistula patients were
L Swell, J Gustafsson, C C Schwartz, L G Halloran, H Danielsson, Z R Vlahcevic   +5 more
doaj   +1 more source

7alpha-Dehydroxylation of cholic acid and chenodeoxycholic acid by Clostridium leptum.

Journal of Lipid Research, 1979
The rate of 7alpha-dehydroxylation of primary bile acids was quantitatively measured radiochromatographically in anaerobically washed whole cell suspensions of Clostridium leptum.
E J Stellwag, P B Hylemon
doaj   +1 more source

Dietary N-3 polyunsaturated fatty acids decrease biliary cholesterol saturation in gallstone disease [PDF]

, 1992
Because fatty acid composition of biliary phospholipids influences cholesterol secretion into bile, we investigated whether replacement of n-1 monounsaturated or n-6 polyunsaturated fatty acids with n-3 polyunsaturated fatty acids in biliary ...
Sven Fischer, Seifferth, Bernd, Paumgartner, Gustav, Holl, Joseph, Frieder Berr, Werner Richter, Joseph Holl, Bernd Seifferth, Jüngst, Dieter, Dieter Jongst, Berr, Frieder, Richter, Werner O., Fischer, Sven, Gustav Paumgartner   +13 more
core   +1 more source