Results 21 to 30 of about 343,812 (340)

Choline metabolism and membrane formation in rat hepatoma cells grown in suspension culture. III. Choline transport and uptake by simple diffusion and lack of direct exchange with phosphatidylcholine

Journal of Lipid Research, 1971
The initial rate of incorporation of methyl-labeled choline into the acid-soluble pool (phosphorylcholine) of Novikoff hepatoma cells growing in suspension culture was investigated as a function of the choline concentration in the medium.
PETER G.W. PLAGEMAEN
doaj   +1 more source

In Vitro Hepatitis C Virus Infection and Hepatic Choline Metabolism

Viruses, 2020
Choline is an essential nutrient required for normal neuronal and muscular development, as well as homeostatic regulation of hepatic metabolism. In the liver, choline is incorporated into the main eukaryotic phospholipid, phosphatidylcholine (PC), and ...
Kaelan Gobeil Odai, Conor O’Dwyer, Rineke Steenbergen, Tyler A. Shaw, Tyler M. Renner, Peyman Ghorbani, Mojgan Rezaaifar, Shauna Han, Marc-André Langlois, Angela M. Crawley, Rodney S. Russell, John P. Pezacki, D. Lorne Tyrrell, Morgan D. Fullerton   +13 more
doaj   +1 more source

Gut Microbiota Targeted Approach in the Management of Chronic Liver Diseases

Frontiers in Cellular and Infection Microbiology, 2022
The liver is directly connected to the intestines through the portal vein, which enables the gut microbiota and gut-derived products to influence liver health.
Jing Liu, Dakai Yang, Xiaojing Wang, Paul Tetteh Asare, Qingwen Zhang, Lixin Na, Lei Shao   +6 more
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Functional genomics with a comprehensive library of transposon mutants for the sulfate-reducing bacterium Desulfovibrio alaskensis G20. [PDF]

, 2014
UnlabelledThe genomes of sulfate-reducing bacteria remain poorly characterized, largely due to a paucity of experimental data and genetic tools. To meet this challenge, we generated an archived library of 15,477 mapped transposon insertion mutants in the
Arkin, Adam P, Davis, Ronald W, Deutschbauer, Adam, Esquivel, Zuelma, Hazen, Terry C, Kazakov, Alexey E, Kuehl, Jennifer V, Kuehn, Raquel, Nguyen, Michelle, Price, Morgan N, Ray, Jayashree, Wetmore, Kelly M   +11 more
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Integrating Choline and Specific Intestinal Microbiota to Classify Type 2 Diabetes in Adults: A Machine Learning Based Metagenomics Study

Frontiers in Endocrinology, 2022
Emerging evidence is examining the precise role of intestinal microbiota in the pathogenesis of type 2 diabetes. The aim of this study was to investigate the association of intestinal microbiota and microbiota-generated metabolites with glucose ...
Qiang Zeng, Mingming Zhao, Mingming Zhao, Fei Wang, Yanping Li, Huimin Li, Huimin Li, Jianqiong Zheng, Xianyang Chen, Xianyang Chen, Xiaolan Zhao, Liang Ji, Xiangyang Gao, Changjie Liu, Yu Wang, Si Cheng, Jie Xu, Bing Pan, Jing Sun, Yongli Li, Dongfang Li, Dongfang Li, Yuan He, Yuan He, Lemin Zheng, Lemin Zheng   +25 more
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Elusive physiological role of prostatic acid phosphatase (PAP): generation of choline for sperm motility via auto-and paracrine cholinergic signaling

Frontiers in Physiology, 2023
Prostatic acid phosphatase (PAP) exists as two splice variants, secreted PAP and transmembrane PAP, the latter of which is implicated in antinociceptive signaling in dorsal root ganglia.
Peter J. Hanley
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Potential of choline chloride - based natural deep eutectic solvents (NaDES) in the extraction of microalgal metabolites [PDF]

, 2017
In a typical chemical process, the solvents are widely used for the dissolution of the reagents, to favor the kinetics and the thermodynamics of a chemical reaction, for the extraction of products, for the separation of mixtures.
Bravi, Marco, Cicci, Agnese, Sed, Giorgia   +2 more
core   +1 more source

Biosynthesis of phosphatidyl choline during prenatal development of the rat lung

Journal of Lipid Research, 1968
The biosynthesis of phosphatidyl choline in rat lung during prenatal development is of interest in connection with the mechanisms of functional development of the lung, particularly in relation to the production of lung surfactant and the control of ...
Paul A. Weinhold
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Vitamin B12 impacts amyloid beta-induced proteotoxicity by regulating the methionine/S-adenosylmethionine cycle

Cell Reports, 2021
Summary: Alzheimer’s disease (AD) is a devastating neurodegenerative disorder with no effective treatment. Diet, as a modifiable risk factor for AD, could potentially be targeted to slow disease onset and progression.
Andy B. Lam, Kirsten Kervin, Jessica E. Tanis   +2 more
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Generation of Choline for Acetylcholine Synthesis by Phospholipase D Isoforms [PDF]

, 2001
DEDICATION: This article is dedicated to the memory of Sue Kim Hanson, a graduate student in the department of Pathology and Laboratory Medicine at Boston University School of Medicine, who perished in the terrorist attacks of September 11, 2001 ...
Blusztajn, Jan Krzysztof, Frohman, Michael A, Zhao, Di   +2 more
core   +3 more sources