F-18-FDG and C-11-choline positron emission tomography in human esophago-gastric cancer : prediction of response to therapy [PDF]
, 2010 Peer reviewedPublisher ...
Hammonds, Solveig +8 more
core +1 more source
Nicotinic α7 acetylcholine receptor-mediated currents are not modulated by the tryptophan metabolite kynurenic acid in adult hippocampal interneurons [PDF]
, 2011 The tryptophan metabolite, kynurenic acid (KYNA), is classically known to be an antagonist of ionotropic glutamate receptors.
Andrew L. Varnell +3 more
core +3 more sources
Response Detection of Castrate-Resistant Prostate Cancer to Clinically Utilised and Novel Treatments by Monitoring Phospholipid Metabolism [PDF]
, 2017 The authors gratefully acknowledge funding from Grampian NHS Endowment. The use of Professor Zanda’s and Jaspar’s NMR equipment and Russell Gray’s assistance are also gratefully acknowledged.Peer reviewedPublisher ...
Alzyoud, Kholoud S +3 more
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Choline dihydrogen phosphate [PDF]
Acta Crystallographica Section E Structure Reports Online, 2009 In the cystal structure of the title compound, (2-hy-droxy-ethyl)trimethylammonium dihydrogen phosphate, C(5)H(14)NO(+)·H(2)PO(4) (-), two anions create dimeric structures via two O-H⋯O hydrogen bonds. The hydrogen-bonded dimers are connected by another O-H⋯O hydrogen bond with the hydroxyl groups of the cations, constructing a columner structure along
Douglas R. MacFarlane +3 more
openaire +4 more sources
In Vitro Hepatitis C Virus Infection and Hepatic Choline Metabolism
Viruses, 2020 Choline is an essential nutrient required for normal neuronal and muscular development, as well as homeostatic regulation of hepatic metabolism. In the liver, choline is incorporated into the main eukaryotic phospholipid, phosphatidylcholine (PC), and ...
Kaelan Gobeil Odai +13 more
doaj +1 more source
In vitro and in silico inhibition performance of choline against CYP1A2, CYP2D6 and CYP3A4
Biotechnology & Biotechnological Equipment, 2022 Choline is an essential nutrient involved in the synthesis of acetylcholine in the cholinergic neurons. The pharmacokinetic properties of choline are well described; however, there is a lack of data about its activity toward the CYP450 superfamily of ...
Emilio Mateev +4 more
doaj +1 more source
Distribution of choline acetyltransferase (ChAT) immunoreactivity in the brain of the teleost cyprinus carpio [PDF]
, 2018 Cholinergic systems play a role in basic cerebral functions and its dysfunction is associated with deficit in neurodegenerative disease. Mechanisms involved in human brain diseases, are often approached by using fish models, especially cyprinids, given ...
Casini, Arianna +3 more
core +2 more sources
Importance of Choline as Essential Nutrient and Its Role in Prevention of Various Toxicities
Prague Medical Report, 2015 Choline is a water-soluble essential nutrient included as a member of the vitamin B12 group owing to its structural similarities with that of the other members of the group.
Somava Biswas, Sarbani Giri
doaj +1 more source
Changes in total choline concentration in the breast of healthy fertile young women in relation to menstrual cycle or use of oral contraceptives: a 3-T 1H-MRS study [PDF]
, 2018 BACKGROUND: To evaluate changes in total choline (tCho) absolute concentration ([tCho]) in the breast of healthy fertile women in relation to menstrual cycle (MC) or use of oral contraceptives (OC).
Di Leo, Giovanni +6 more
core +2 more sources
Scientific ReportsDetermining the content of the nutrient choline in foods and obtaining the required amount from the diet are crucial. One way to measure choline in foods is by converting choline esters to free choline via acid hydrolysis, followed by quantifying the ...
Yoshinari Hirakawa +6 more
doaj +1 more source