Results 31 to 40 of about 343,812 (340)

Dietary Choline Intake: Current State of Knowledge Across the Life Cycle

Nutrients, 2018
Choline, an essential dietary nutrient for humans, is required for the synthesis of the neurotransmitter, acetylcholine, the methyl group donor, betaine, and phospholipids; and therefore, choline is involved in a broad range of critical physiological ...
Alejandra M Wiedeman, S. Barr, T. Green, Zhaoming Xu, S. Innis, D. Kitts   +5 more
semanticscholar   +1 more source

Meta-analysis of the effects of supplemental rumen-protected choline during the transition period on performance and health of parous dairy cows.

Journal of Dairy Science, 2020
The objectives were to use meta-analytic methods to determine the effects of amount of supplemental choline ion as rumen-protected choline (RPC) starting prepartum on production and health of dairy cows.
U. Arshad, M. Zenobi, C. Staples, J.E.P. Santos   +3 more
semanticscholar   +1 more source

Comparative genomics and mutagenesis analyses of choline metabolism in the marine Roseobacter clade [PDF]

, 2015
Choline is ubiquitous in marine eukaryotes and appears to be widely distributed in surface marine waters; however, its metabolism by marine bacteria is poorly understood.
Andresen P.A., Gauthier M.J., Ghoul M., Ikawa M., Kiene R.P., Nau‐Wagner G., Prado S.   +6 more
core   +1 more source

Potential TMA-Producing Bacteria Are Ubiquitously Found in Mammalia

Frontiers in Microbiology, 2020
Human gut bacteria metabolize dietary components such as choline and carnitine to trimethylamine (TMA) that is subsequently oxidized to trimethylamine-N-oxide (TMAO) by hepatic enzymes.
Silke Rath, Tatjana Rud, Dietmar H. Pieper, Marius Vital, Marius Vital   +4 more
doaj   +1 more source

Biochemical characterization of the initial steps of the Kennedy pathway in Trypanosoma brucei:the ethanolamine and choline kinases [PDF]

, 2008
Note related output below contains correction of this paper.Ethanolamine and choline are major components of the trypanosome membrane phospholipids, in the form of GPEtn (glycero-phosphoethanolamine) and GPCho (glycerophosphocholine).
Ayoama, Baba, Bürgemaister, Chang, Choubey, Clary, Cuadrado, Dowhan, Federica Gibellini, Ferguson, Gee, Imhof, Kennedy, Kim, Kim, Malito, Menon, Menon, Nagamune, Patnaik, Peisach, Rifkin, Scheef, Smith, Terry K. Smith, Urbina, Wharfe, William N. Hunter, Yuan   +28 more
core   +7 more sources

Anticancer activity of rutin and its combination with ionic liquids on renal cells [PDF]

, 2020
The renal cell carcinoma (RCC) is the most common type of kidney cancer. Identifying novel and more effective therapies, while minimizing toxicity, continues to be fundamental in curtailing RCC.
Araújo, Maria Eduarda Machado, Baby, André Rolim, Caparica, Rita, Costa, João Guilherme, Fonte, Pedro, Júlio, Ana, Santos de Almeida, Tânia   +6 more
core   +1 more source

Measurement of plasma choline in acute coronary syndrome: importance of suitable sampling conditions for this assay

Scientific Reports, 2018
Blood choline has been proposed as a predictor of acute coronary syndrome (ACS), however different testing procedures might affect the choline concentration because the lysophospholipase D activity of autotaxin (ATX) can convert lysophosphatidylcholine ...
Ryunosuke Ohkawa, Makoto Kurano, Noboru Sakai, Tatsuya Kishimoto, Takahiro Nojiri, Koji Igarashi, Shigemi Hosogaya, Yukio Ozaki, Tomotaka Dohi, Katsumi Miyauchi, Hiroyuki Daida, Junken Aoki, Shigeo Okubo, Hitoshi Ikeda, Minoru Tozuka, Yutaka Yatomi   +15 more
doaj   +1 more source

Intestinal Microbiota Composition Modulates Choline Bioavailability from Diet and Accumulation of the Proatherogenic Metabolite Trimethylamine-N-Oxide

mBio, 2015
Choline is a water-soluble nutrient essential for human life. Gut microbial metabolism of choline results in the production of trimethylamine (TMA), which upon absorption by the host is converted in the liver to trimethylamine-N-oxide (TMAO).
Kymberleigh A. Romano, E. Vivas, D. Amador-Noguez, F. Rey   +3 more
semanticscholar   +1 more source

Distribution of choline acetyltransferase (ChAT) immunoreactivity in the brain of the teleost cyprinus carpio [PDF]

, 2018
Cholinergic systems play a role in basic cerebral functions and its dysfunction is associated with deficit in neurodegenerative disease. Mechanisms involved in human brain diseases, are often approached by using fish models, especially cyprinids, given ...
Casini, Arianna, Cioni, Carla, Toni, Mattia, Vaccaro, Rosa   +3 more
core   +2 more sources

Response Detection of Castrate-Resistant Prostate Cancer to Clinically Utilised and Novel Treatments by Monitoring Phospholipid Metabolism [PDF]

, 2017
The authors gratefully acknowledge funding from Grampian NHS Endowment. The use of Professor Zanda’s and Jaspar’s NMR equipment and Russell Gray’s assistance are also gratefully acknowledged.Peer reviewedPublisher ...
Alzyoud, Kholoud S, Phyu, Su Myat, Smith, Tim A D, Tseng, Chih-Chung   +3 more
core   +2 more sources