Results 61 to 70 of about 343,812 (340)

Methylation of guanidoacetic acid by homocystine plus choline with rat liver slices [PDF]

, 1945
The methylation of guanidoacetic acid by liver slices is accelerated by methionine; choline, under these conditions, exerts no significant accelerating effect (1).
Borsook, Henry, Dubnoff, Jacob W.
core  

Implications of trimethylamine N-oxide (TMAO) and Betaine in Human Health: Beyond Being Osmoprotective Compounds

Frontiers in Molecular Biosciences, 2022
Osmolytes are naturally occurring small molecular weight organic molecules, which are accumulated in large amounts in all life forms to maintain the stability of cellular proteins and hence preserve their functions during adverse environmental conditions.
Ashal Ilyas, Yasanandana Supunsiri Wijayasinghe, Ilyas Khan, Nourhan M. El Samaloty, Mohd Adnan, Tanveer Ali Dar, Nitesh Kumar Poddar, Laishram R. Singh, Hemlata Sharma, Shahanavaj Khan, Shahanavaj Khan   +10 more
doaj   +1 more source

Choline: Exploring the Growing Science on Its Benefits for Moms and Babies

Nutrients, 2019
The importance of ensuring adequate choline intakes during pregnancy is increasingly recognized. Choline is critical for a number of physiological processes during the prenatal period with roles in membrane biosynthesis and tissue expansion ...
Hunter W. Korsmo, Xinyin Jiang, M. Caudill   +2 more
semanticscholar   +1 more source

C9orf72 ALS‐causing mutations lead to mislocalization and aggregation of nucleoporin Nup107 into stress granules

FEBS Letters, EarlyView.
Mutations in the C9orf72 gene represent the most common genetic cause of amyotrophic lateral sclerosis (ALS), a fatal neurodegenerative disease. Using patient‐derived neurons and C. elegans models, we find that the nucleoporin Nup107 is dysregulated in C9orf72‐associated ALS. Conversely, reducing Nup107 levels mitigates disease‐related changes.
Saygın Bilican, Yara Nabawi, William Hongyu Zhang, Dunja Petrovic, Markus Wehrmann, Sara Muñoz‐García, Seda Koyuncu, David Vilchez   +7 more
wiley   +1 more source

Modulation of DNA Methyltransferase 1 Profile by γ-lrradiation Followed by Methyl Donor Starvation

Pteridines, 2005
Role of one-carbon transfer agents methyl donors namely folate, choline and methionine in DNA methylation has been the subject of extensive investigation.
Batra Vipen, Kesavan Vellappan, Mishra Kaushala P.   +2 more
doaj   +1 more source

Updating Nutritional Data and Evaluation of Technological Parameters of Italian Milk

Foods, 2013
Different technologically treated Italian milks (whole and semi-skimmed ultra-high temperature (UHT), pasteurized and microfiltered milk), collected from 2009 to 2012, were evaluated for nutritional and technological properties.
Pamela Manzi, Maria Gabriella Di Costanzo, Maria Mattera   +2 more
doaj   +1 more source

The Phospholipid N-Methyltransferase and Phosphatidylcholine Synthase Pathways and the ChoXWV Choline Uptake System Involved in Phosphatidylcholine Synthesis Are Widely Conserved in Most, but Not All Brucella Species

Frontiers in Microbiology, 2021
The brucellae are facultative intracellular bacteria with a cell envelope rich in phosphatidylcholine (PC). PC is abundant in eukaryotes but rare in prokaryotes, and it has been proposed that Brucella uses PC to mimic eukaryotic-like features and avoid ...
Beatriz Aragón-Aranda, Leyre Palacios-Chaves, Miriam Salvador-Bescós, María Jesús de Miguel, María Jesús de Miguel, Pilar M. Muñoz, Pilar M. Muñoz, Miguel Ángel Vences-Guzmán, Amaia Zúñiga-Ripa, Leticia Lázaro-Antón, Christian Sohlenkamp, Ignacio Moriyón, Maite Iriarte, Raquel Conde-Álvarez   +13 more
doaj   +1 more source

From lactation to malignancy: A comparison between healthy and cancerous breast gland at single‐cell resolution reveals new issues for tumorigenesis

FEBS Letters, EarlyView.
Single‐cell RNA sequencing reveals an opposite role of SLPI in basal tumors based on metastatic spread, along with shared activation of specific regulons in cancer cells and mature luminal lactocytes, as well as downregulation of MALAT1 and NEAT1 in the latter.
Pietro Ancona, Carlo M. Bergamini, Carlo Ferrari, Stefano Volinia, Nicoletta Bianchi   +4 more
wiley   +1 more source

How do nematodes transfer phosphorylcholine to carbohydrates? [PDF]

, 2010
An unusual aspect of the biology of nematodes is the attachment of phosphorylcholine (PC) to carbohydrate. The attachment appears to play an important role in nematode development and, in some parasitic species, in immunomodulation.
Harnett, W., Houston, K.M., Rzepecka, J.
core   +1 more source

Dietary Reference Values for choline

EFSA Journal, 2016
Following a request from the European Commission, the EFSA Panel on Dietetic Products, Nutrition and Allergies (NDA) derives Dietary Reference Values (DRVs) for choline.
EFSA Panel on Dietetic Products, Nutrition and Allergies (NDA)
doaj   +1 more source