Results 61 to 70 of about 236,274 (244)
A Brief History of Choline [PDF]
Annals of Nutrition and Metabolism, 2012 In 1850, Theodore Gobley, working in Paris, described a substance, ‘lecithine’, which he named after the Greek ‘lekithos’ for egg yolk. Adolph Strecker noted in 1862 that when lecithin from bile was heated, it generated a new nitrogenous chemical that he named ‘choline’.
openaire +3 more sources
Gelsolin's Protective Role in MASH through F‐Actin Regulation and P53 Degradation
Advanced Science, EarlyView.Gelsolin (GSN) maintains liver metabolic homeostasis by promoting MDM2‐mediated P53 degradation and inhibiting F‐actin/Yes‐associated protein (YAP) overactivation. Loss of GSN impairs P53 degradation, increases lipid deposition, and enhances YAP‐driven fibrosis and inflammation in metabolic‐associated steatohepatitis.
Yiwei Lu +9 more
wiley +1 more source
Imaging biochemistry: applications to breast cancer. [PDF]
, 2001 The use of magnetic resonance spectroscopy (MRS) to investigate breast tumour biochemistry in vivo is reviewed. To this end, results obtained both from patients in vivo and from tumour extracts and model systems are discussed.
Leach, MO, Ronen, SM
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Advanced Science, EarlyView.Salivary metabolic signatures associated with lung cancer are systematically characterized through a self‐developed high‐throughput mass spectrometry Lab‐on‐a‐Chip platform. Utilizing these metabolic fingerprints, SalivaMLD, an integrated machine‐learning‐driven classification model is developed and demonstrates superior performance in detecting lung ...
Shuang Lin +17 more
wiley +1 more source
Fingolimod modulates microglial activation to augment markers of remyelination [PDF]
, 2011 This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work ...
Baker, D, Giovannoni, G, Jackson, SJ
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Microglial MS4A4A Protects against Epileptic Seizures in Alzheimer's Disease
Advanced Science, EarlyView.This study has unveiled significant new insights into the role of MS4A4A in Alzheimer's disease‐related epilepsy, highlighting its impact on microglial phagocytosis, mitochondrial metabolism, and cytoskeleton, and demonstrating its therapeutic potential in epilepsy management.
Meng Jiang +10 more
wiley +1 more source
Unenhanced whole-body MRI versus PET-CT for the detection of prostate cancer metastases after primary treatment [PDF]
, 2016 The aim of this study was to evaluate the accuracy of unenhanced whole-body MRI, including whole-body Diffusion Weighted Imaging (DWI), used as a diagnostic modality to detect pathologic lymph nodes and skeletal metastases in patients with prostate ...
AL ANSARI, Najwa +10 more
core
Structure-function relations in phosphorylcholine-binding mouse myeloma proteins [PDF]
, 1977 The binding site interactions between the phosphorylcholine (phosphocholine)-binding mouse myeloma proteins TEPC 15, W3207, McPC 603, MOPC 167, and MOPC 511 and the isotopically substituted hapten phosphoryl-[methyl-13C]choline have been investigated ...
Goetze, Andrew M., Richards, John H.
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Advanced Science, EarlyView.During the mechanical crushing of retired lithium‐ion batteries, aluminum foil from current collectors may penetrate NCM active crystals through frictional contact, forming more stable Al─O bonds. The dissolution behavior of critical metals in NCM cathodes will be influenced to varying extents by different mechanisms in various hydrometallurgical ...
Kang Liu +5 more
wiley +1 more source