Results 91 to 100 of about 195,821 (248)

Theta oscillations, epileptogenesis, and focal seizures in rodent models of mesial temporal lobe epilepsy

open access: yesEpilepsia, EarlyView.
Abstract Theta oscillations (4–12 Hz) are a prominent network rhythm within hippocampal and parahippocampal structures. Driven by cholinergic and γ‐aminobutyric acidergic inputs originating from the medial septum, physiological theta gates network excitability to control spatial navigation, memory encoding, and sensorimotor integration during specific ...
Maxime Lévesque, Massimo Avoli
wiley   +1 more source

Precision therapies for genetic epilepsies in 2025: Promises and pitfalls

open access: yesEpilepsia Open, EarlyView.
Abstract By targeting the underlying etiology, precision therapies offer an exciting paradigm shift to improve the stagnant outcomes of drug‐resistant epilepsies, including developmental and epileptic encephalopathies. Unlike conventional antiseizure medications (ASMs) which only treat the symptoms (seizures) but have no effect on the underlying ...
Shuyu Wang   +3 more
wiley   +1 more source

Immediate early gene expression in the mesopontine tegmentum and midbrain after acute or chronic nicotine administration [PDF]

open access: yes, 2008
The reinforcing properties of nicotine depend partly on cholinergic projections from the pedunculopontine tegmental (PPTg) and laterodorsal tegmental (LDTg) nuclei to midbrain dopamine neurons in the ventral tegmental area (VTA) and substantia nigra pars
Porter, Ailsa
core   +2 more sources

Role of the cholinergic system in the psychopathology and treatment of schizophrenia: a protocol for a scoping review

open access: yesFrontiers in Psychiatry
Introduction and objectiveThe cholinergic system has broad implications for affective and cognitive processes, which makes it pertinent for the psychopathology and treatment of mental disorders.
Michal Haczkiewicz   +4 more
doaj   +1 more source

Neonatal seizures and GABAergic drugs: Scylla and Charybdis?

open access: yesEpilepsia Open, EarlyView.
Abstract Neonates have a high incidence of seizures that are frequently difficult to control with conventional first‐line anti‐seizure medications, which are gamma‐aminobutyric acid (GABA) agonists. The reasons for this clinical problem are multifold but are likely related to the unique physiology of the immature nervous system. Specifically, the early
Kerry W. Thompson   +2 more
wiley   +1 more source

Herbal Supplement Consumption: A Rare Case of Cholinergic Syndrome [PDF]

open access: yes
Dietary supplements for weight loss are widely marketed without true regularization. The use of such non-medical supplements is increasing, as they are often perceived to be natural and harmless.
Ömer Yusuf ERDURMUŞ   +2 more
core   +1 more source

Chemical coding and chemosensory properties of cholinergic brush cells in the mouse gastrointestinal and biliary tract

open access: yesFrontiers in Physiology, 2015
The mouse gastro-intestinal and biliary tract mucosal epithelia harbor choline acetyltransferase (ChAT)-positive brush cells with taste cell-like traits.
Burkhard eSchütz   +12 more
doaj   +1 more source

Sleep Health in Bulimia Nervosa: A Systematic Review

open access: yesEuropean Eating Disorders Review, EarlyView.
ABSTRACT Objective Research on sleep in bulimia nervosa (BN) is methodologically varied and yields inconsistent findings. This review synthesised BN‐sleep studies and examined whether comorbid mood disorders contribute to sleep disturbance. Method PsycINFO, Medline (Ovid), and Scopus were searched for English or French quantitative studies comparing ...
Samantha Kenny   +4 more
wiley   +1 more source

Connectivity, plasticity, and function of neuronal circuits in the zebrafish olfactory forebrain [PDF]

open access: yes, 2014
For most living animals such as worms, insects, fishes, rodents and humans, chemical cues from the environment (odorants) play critical roles in guiding behaviors important for survival, including preying, mating, breeding, and escaping.
Zou, Ming
core   +1 more source

Oscillometric assessment of bronchodilator response in horses with severe asthma during remission

open access: yesEquine Veterinary Journal, EarlyView.
Abstract Background During clinical remission of severe equine asthma (SEA), affected animals can be challenging to distinguish from healthy horses. In humans, the degree of bronchodilation achieved with a β2‐adrenergic bronchodilator is helpful in differentiating asthmatics from healthy subjects.
Séléna de Wasseige   +2 more
wiley   +1 more source

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