Results 101 to 110 of about 167,062 (267)

Functional Magnetic Resonance Imaging (fMRI) Signatures of Progression and Phenoconversion in Prodromal Synucleinopathies

Movement Disorders, EarlyView.
Abstract Background Isolated rapid eye movement (REM) sleep behavior disorder (iRBD) is a prodromal manifestation of synucleinopathies and provides a critical window to identify early markers of progression to Parkinson's disease (PD) and dementia with Lewy bodies (DLB).
Lachlan Churchill, Anna Ignatavicius, Ajay Konuri, Jack Anderson, Natasha Taylor, Simon J.G. Lewis, Elie Matar   +6 more
wiley   +1 more source

Cholinergic Neuronal Modulation Alters Dopamine D₂Receptor Availability In Vivo by Regulating Receptor Affinity Induced by Facilitated Synaptic Dopamine Turnover: Positron Emission Tomography Studies with Microdialysis in the Conscious Monkey Brain [PDF]

, 2000
Hideo Tsukada, Norihiro Harada, Shingo Nishiyama, Hiroyuki Ohba, Takeharu Kakiuchi   +4 more
openalex   +1 more source

Vagus Nerve Stimulation in Movement Disorders, from Principles to a Systematic Review of Evidence

Movement Disorders, EarlyView.
Abstract Background The vagus nerve (VN), the principal component of the parasympathetic branch of the autonomic nervous system (ANS), mediates bidirec communication between the central nervous system (CNS) and peripheral organs. Vagus nerve stimulation (VNS), delivered through invasive (iVNS) or non‐invasive (transcutaneous cervical [tcVNS] and ...
Francesca Proietti, Matteo Maria Ottaviani, Elisabetta Burchi, Giorgio Vivacqua, Gaia Anzini, Riccardo Antonio Ricciuti, Fioravante Capone, Vaughan G. Macefield, Vincenzo Di Lazzaro, Massimo Marano   +9 more
wiley   +1 more source

Demonstration of a Simple Epitope Tag Multimerization Strategy for Enhancing the Sensitivity of Protein Detection Using Drosophila vAChT

G3: Genes, Genomes, Genetics, 2020
Kole V. Tison, Hannah M. McKinney, R. Steven Stowers   +2 more
doaj   +1 more source

Cholinergic basal forebrain neurons regulate vascular dynamics and cerebrospinal fluid flux [PDF]

Kai‐Hsiang Chuang, Xiaoqing Zhou, Ying Xia, Zengmin Li, Lei Qian, Eamonn Eeles, Grace Ngiam, Jürgen Fripp, Elizabeth J. Coulson   +8 more
openalex   +1 more source

Analyzing the ‘Bradykinesia Complex’ in Parkinson's Disease

Movement Disorders, EarlyView.
Abstract Background Bradykinesia is the hallmark sign of parkinsonism. We recently proposed redefining bradykinesia as a complex of motor abnormalities, each reflecting separate pathophysiological elements. Objective To analyze the ‘bradykinesia complex’ in Parkinson's disease (PD) and healthy elderly individuals.
Giulia Paparella, Martina De Riggi, Antonio Cannavacciuolo, Daniele Birreci, Davide Costa, Luca Angelini, Danilo Alunni Fegatelli, Alfonso Fasano, Alberto J. Espay, Matteo Bologna   +9 more
wiley   +1 more source

The Second Hit Hypothesis in Animal and Human Dystonia: The Role of Peripheral Nerve Trauma and Spinal Cord Injury

Movement Disorders, EarlyView.
The “second‐hit” hypothesis proposes that both a genetic predisposition and an environmental insult—such as peripheral nerve trauma or spinal cord injury—are required for dystonia development. This review explores how neuroinflammation and maladaptive plasticity, triggered by nerve and spinal cord injury, contribute to dystonia pathogenesis.
Lisa Harder‐Rauschenberger, Chi Wang Ip   +1 more
wiley   +1 more source

Hippocampal Cholinergic Neurostimulating Peptide Suppresses Acetylcholine Synthesis in T Lymphocytes

, 2018
Yuka Saito, Masato Mashimo, Akari Nobeyama, Kana Murakami, Takeshi Fujii   +4 more
openalex   +2 more sources

Altered Hippocampal Transcriptomic Profile Reveals Cognitive Impairment in Young Metabolically Obese, Normal‐Weight Rats, Prevented by Perinatal Leptin Intake

Molecular Nutrition &Food Research, EarlyView.
Early‐life exposure of rats to high‐fat‐isocaloric diet leads to metabolically obese, normal‐weight phenotype, and impaired cognition. Hippocampal transcriptomic analysis reveals disruption in pathways linked to obesity and cognitive decline, which is mitigated by perinatal leptin supplementation. PBMC share common altered genes with hippocampus, which
Carmen García‐Ruano, Andrea Costa, Andreu Palou, Paula Oliver   +3 more
wiley   +1 more source

Autoradiographic quantification of muscarinic cholinergic synaptic markers in bat, shrew, and rat brain

, 1994
Roger L. Albin, Morgan M. Howland, Donald S. Higgins, Kirk A. Frey   +3 more
openalex   +2 more sources