Results 121 to 130 of about 195,821 (248)
Brain cholinergic dysfunction in obese Zucker LEPR(fa/fa) rats
, 2016 Increased food intake, reduced physical activity and altered metabolic processes are variables affecting energy balance inducing obesity. Obesity is now considered an increasingly medical challenge associated with the development of chronic diseases ...
AMENTA, Francesco +4 more
core +1 more source
Movement Disorders Clinical Practice, EarlyView.Abstract Background Parkinson's disease (PD) is clinically heterogeneous, with variable progression rates that complicate clinical trial design. The data‐driven diffuse malignant (DM), intermediate (IM), and mild‐motor predominant (MMP) subtyping model has prognostic value but lacks disease duration–specific thresholds for prospective use in disease ...
Ahmed Negida +4 more
wiley +1 more source
Apathy in Lewy Body Disorders: A Position Paper
Movement Disorders, EarlyView.Abstract Apathy is one of the most prevalent and disabling non‐motor symptoms in Parkinson's disease (PD) and dementia with Lewy bodies (DLB), collectively referred to as Lewy body disorders (LBDs). It is associated with reduced quality of life, accelerated cognitive decline, increased caregiver burden, and poorer functional outcomes, yet remains ...
Jaime Kulisevsky +12 more
wiley +1 more source
Movement Disorders, EarlyView.Abstract Gastrointestinal dysfunction is increasingly recognized as a core feature of Parkinson's disease (PD), affecting quality of life, nutrition, medication response, and potentially the earliest stages of pathogenesis. This perspective traces the evolution of the gut from a neglected source of non‐motor symptoms to a central component of ...
Filip Scheperjans +4 more
wiley +1 more source
Emergencies in Amyotrophic Lateral Sclerosis
Muscle &Nerve, EarlyView.ABSTRACT Emergencies are frequent in people living with amyotrophic lateral sclerosis (pALS), especially as the disease progresses, and can necessitate urgent evaluation and intervention. Progressive weakness in ALS inevitably increases fall risk, making discussion of fall prevention strategies integral to caring for pALS.
S. Pinar Uysal +9 more
wiley +1 more source
Epilepsia OpenObjective A benzodiazepine (diazepam or midazolam) is one of the current standards of care therapies to effectively terminate organophosphorus nerve agent‐induced status epilepticus when administered shortly after onset.
Hailey G. Steier +8 more
doaj +1 more source
Repurposing antimicrobial agents for neuroprotection: Mechanisms, clinical potential, and challenges
Neuroprotection, EarlyView.Antimicrobial agents exert neuroprotective effects through modulation of interconnected pathways. Tetracyclines, macrolides, antimalarial agents, sulfones, and antiparasitic agents suppress neuroinflammation, oxidative stress, and apoptosis while preserving mitochondrial function and neurotransmission.
Mohammad Amin Manavi +5 more
wiley +1 more source
Otolaryngology–Head and Neck Surgery, EarlyView.Abstract Objective To systematically review and synthesize outcomes following sialendoscopy in patients with salivary gland dysfunction and a history of radioactive iodine (RAI). Data Sources A comprehensive search of Medline, Embase, and Cochrane Library was conducted from database inception through December 26, 2025.
Michal Kulasek +2 more
wiley +1 more source
Phytotherapy Research, EarlyView.ABSTRACT Alzheimer's disease (AD) is a progressive neurodegenerative disorder associated with cognitive decline and neuroinflammation. Xanthoceras sorbifolia Bunge oil (XSBO), a woody plant oil rich in bioactive fatty acids, has shown potential health benefits.
Lijing Du +8 more
wiley +1 more source