Results 21 to 30 of about 285,894 (338)
Distribution of choline acetyltransferase (ChAT) immunoreactivity in the brain of the teleost cyprinus carpio [PDF]
, 2018 Cholinergic systems play a role in basic cerebral functions and its dysfunction is associated with deficit in neurodegenerative disease. Mechanisms involved in human brain diseases, are often approached by using fish models, especially cyprinids, given ...
Casini, Arianna +3 more
core +2 more sources
Brain muscarinic cholinergic receptors in Huntington's disease [PDF]
, 1992 Muscarinic cholinergic receptors and choline acetyltransferase (ChAT) activity were studied in postmortem brain tissue from patients with Huntington's disease and matched control subjects.
Agid, Y. +4 more
core +1 more source
Frontiers in Physiology, 2015 The mouse gastro-intestinal and biliary tract mucosal epithelia harbor choline acetyltransferase (ChAT)-positive brush cells with taste cell-like traits.
Burkhard eSchütz +12 more
doaj +1 more source
The cholinergic system in the pathophysiology and treatment of Alzheimer's disease.
Brain : a journal of neurology, 2018 Cholinergic synapses are ubiquitous in the human central nervous system. Their high density in the thalamus, striatum, limbic system, and neocortex suggest that cholinergic transmission is likely to be critically important for memory, learning, attention
H. Hampel +11 more
semanticscholar +1 more source
Elevated Hippocampal Cholinergic Neurostimulating Peptide precursor protein (HCNP-pp) mRNA in the amygdala in major depression [PDF]
, 2015 The amygdala is innervated by the cholinergic system and is involved in major depressive disorder (MDD). Evidence suggests a hyper-activate cholinergic system in MDD.
Argibay, Pablo +3 more
core +1 more source
Alzheimer's Disease: Targeting the Cholinergic System
Current Neuropharmacology, 2016 Acetylcholine (ACh) has a crucial role in the peripheral and central nervous systems. The enzyme choline acetyltransferase (ChAT) is responsible for synthesizing ACh from acetyl-CoA and choline in the cytoplasm and the vesicular acetylcholine transporter
T. H. Ferreira-Vieira +3 more
semanticscholar +1 more source
Muscarinic receptor M3 activation promotes fibrocytes contraction
Frontiers in Pharmacology, 2022 Fibrocytes are monocyte-derived cells able to differentiate into myofibroblasts-like cells. We have previously shown that they are increased in the bronchi of Chronic Obstructive Pulmonary Disease (COPD) patients and associated to worse lung function ...
Pauline Henrot +19 more
doaj +1 more source
Epilepsia Open, EarlyView., 2022 Abstract Epilepsy is a heterogeneous disorder characterized by spontaneous seizures and behavioral comorbidities. The underlying mechanisms of seizures and epilepsy across various syndromes lead to diverse clinical presentation and features. Similarly, animal models of epilepsy arise from numerous dissimilar inciting events.
Melissa Barker‐Haliski +3 more
wiley +1 more source
Frontiers in Endocrinology, 2023 The striatum is an essential component of the basal ganglia that is involved in motor control, action selection and motor learning. The pathophysiological changes of the striatum are present in several neurological and psychiatric disorder including ...
Erzsébet Kövesdi +17 more
doaj +1 more source
Central Cholinergic Nervous System and Cholinergic Agents [PDF]
Acta Medica (Hradec Kralove, Czech Republic), 1998 Central cholinergic nervous system play important role in many physiological and behavioral functions in humans. The activity of the cholinergic nervous system depends upon the production and fate of acetylcholine and all compounds influenced its biosynthesis, storage, release, hydrolysis, interaction with different subtypes of cholinergic receptors ...
openaire +3 more sources