Results 31 to 40 of about 195,821 (248)

Cholinergic cells in the nucleus basalis of mice express the N-methyl-D-aspartate-receptor subunit NR2C and its replacement by the NR2B subunit enhances frontal and amygdaloid acetylcholine levels [PDF]

, 2006
It is known that glutamatergic and cholinergic systems interact functionally at the level of the cholinergic basal forebrain. The N-methyl-D-aspartate receptor (NMDA-R) is a multiprotein complex composed of NR1, NR2 and/or NR3 subunits.
Dolga, A.,, Eisel, U.L.M.,, Dolga, Amalia, Dere, E., I. Pieri, L. Marchetti, Dere, E.,, Pieri, I., Marchetti, L., De Souza Silva, M. A., Huston, J. P., Marchetti, L.,, A. Dolga, J. P. Huston, Dolga, Amalia; id_orcid, U. L. M. Eisel, Huston, J.P.,, Pieri, I.,, Eisel, U. L. M., Souza Silva, M.A. De,, E. Dere, M. A. De Souza Silva, Eisel, U. L. M.; id_orcid   +22 more
core   +1 more source

Cell type-specific long-range connections of basal forebrain circuit

eLife, 2016
The basal forebrain (BF) plays key roles in multiple brain functions, including sleep-wake regulation, attention, and learning/memory, but the long-range connections mediating these functions remain poorly characterized.
Johnny Phong Do, Min Xu, Seung-Hee Lee, Wei-Cheng Chang, Siyu Zhang, Shinjae Chung, Tyler J Yung, Jiang Lan Fan, Kazunari Miyamichi, Liqun Luo, Yang Dan   +10 more
doaj   +1 more source

Pro-cognitive drug effects modulate functional brain network organization

Frontiers in Behavioral Neuroscience, 2012
Previous studies document that cholinergic and noradrenergic drugs improve attention, memory and cognitive control in healthy subjects and patients with neuropsychiatric disorders.
Carsten eGiessing, Christiane M Thiel
doaj   +1 more source

Accidental organophosphate poisoning: A case series of 2 pediatric coumaphos exposures

Journal of the American College of Emergency Physicians Open, 2022
Introduction Pediatric organophosphate insecticide poisonings are rare in the United States, and life‐threatening toxicity is rarely seen. We report 2 accidental ingestions of the organophosphate insecticide coumaphos that resulted in life‐threatening ...
Justin A. Seltzer, Sarah Friedland, Nathan A. Friedman, Garret A. Winkler, Emily Foreman, Yousef Al Mubarak, Brent Buccine, Branden Engorn, Allyson Kreshak, Alicia Minns, Christian A. Tomaszewski, Daniel R. Lasoff, Richard F. Clark   +12 more
doaj   +1 more source

The PPN and motor control: Preclinical studies to deep brain stimulation for Parkinson’s disease

Frontiers in Neural Circuits, 2023
The pedunculopontine nucleus (PPN) is the major part of the mesencephalic locomotor region, involved in the control of gait and locomotion. The PPN contains glutamatergic, cholinergic, and GABAergic neurons that all make local connections, but also have ...
Caixia Lin, Caixia Lin, Margreet C. Ridder, Pankaj Sah, Pankaj Sah   +4 more
doaj   +1 more source

Linking actions to outcomes : the role of the posterior pedunculopontine tegmental nucleus in instrumental learning [PDF]

, 2012
Located in the mesopontine tegmentum, the pedunculopontine tegmental nucleus (PPTg) is comprised principally of glutamatergic, cholinergic and GABAergic neurons.
MacLaren, Duncan A. A.
core   +2 more sources

Adaptive short‐term associative conditioning in the pancreatic β‐cell

Physiological Reports, 2020
This study associates cholinergic stimulation of the pancreatic β‐cell electrical activity with a short‐term memory phenomenon. Glucose pulses applied to a basal glucose concentration induce depolarizing waves which are used to estimate the evolution of ...
Juan V. Sanchez‐Andres, Raquel Pomares, Willy J. Malaisse   +2 more
doaj   +1 more source

Distinct Chrna5 mutations link excessive alcohol use to types I/II vulnerability profiles and IPN GABAergic neurons

Translational Psychiatry
Genome wide association and animal studies have implicated genetic variations in CHRNΑ5, encoding the α5 subunit-containing nicotinic acetylcholine receptors (α5*nAChRs), as a risk factor for developing alcohol use disorders (AUDs).
Léa Tochon, Nadia Henkous, Morgane Besson, Uwe Maskos, Vincent David   +4 more
doaj   +1 more source

The Brilliance of the Zebrafish Model: Perception on Behavior and Alzheimer’s Disease

Frontiers in Behavioral Neuroscience, 2022
Alzheimer’s disease (AD) has become increasingly prevalent in the elderly population across the world. It’s pathophysiological markers such as overproduction along with the accumulation of amyloid beta (Aβ) plaques and neurofibrillary tangles (NFT) are ...
Avinash Shenoy, Meheli Banerjee, Archana Upadhya, Siddhi Bagwe-Parab, Ginpreet Kaur   +4 more
doaj   +1 more source

Long‐Term Efficacy of Immunotherapy in Autoimmune Autonomic Ganglionopathy—A 10‐Year Follow Up Study

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Autoimmune autonomic ganglionopathy (AAG) is a rare but potentially treatable cause of severe autonomic failure. Evidence guiding long‐term immunotherapy, treatment sequencing, and residual autonomic impairment is limited. We evaluated long‐term treatment response, residual autonomic dysfunction, and relapse patterns in patients with
Giacomo Chiaro, Shiwen Koay, Gordon T. Ingle, Patricia McNamara, Laura Watson, Fion Bremner, Valeria Iodice   +6 more
wiley   +1 more source