Results 51 to 60 of about 345,248 (352)
SYMPATHETIC POSTGANGLIONIC CHOLINERGIC FIBRES [PDF]
British Journal of Pharmacology, 1960 When the postganglionic fibres to the nictitating membrane are stimulated in a cat treated with reserpine, the membrane contracts. The contraction is increased after the injection of eserine and is abolished with atropine. Thus the fibres stimulated appear to be cholinergic.
J H, BURN, M J, RAND
openaire +4 more sources
Adaptive short‐term associative conditioning in the pancreatic β‐cell
Physiological Reports, 2020 This study associates cholinergic stimulation of the pancreatic β‐cell electrical activity with a short‐term memory phenomenon. Glucose pulses applied to a basal glucose concentration induce depolarizing waves which are used to estimate the evolution of ...
Juan V. Sanchez‐Andres +2 more
doaj +1 more source
Expression and Function of the Cholinergic System in Immune Cells
Frontiers in Immunology, 2017 T and B cells express most cholinergic system components—e.g., acetylcholine (ACh), choline acetyltransferase (ChAT), acetylcholinesterase, and both muscarinic and nicotinic ACh receptors (mAChRs and nAChRs, respectively).
T. Fujii +6 more
semanticscholar +1 more source
Translational PsychiatryGenome wide association and animal studies have implicated genetic variations in CHRNΑ5, encoding the α5 subunit-containing nicotinic acetylcholine receptors (α5*nAChRs), as a risk factor for developing alcohol use disorders (AUDs).
Léa Tochon +4 more
doaj +1 more source
Cell type-specific regulation of choline acetyltransferase gene expression - Role of the neuron-restrictive silencer element and cholinergic-specific enhancer [PDF]
, 1996 This study demonstrates the presence of positive and negative regulatory elements within a 2336-base pair-long region of the rat choline acetyltransferase (ChAT) gene promoter that cooperate to direct cell type-specific expression in cholinergic cells. A
Anderson, David J. +3 more
core
Single copy/knock-in models of ALS SOD1 in C. elegans suggest loss and gain of function have different contributions to cholinergic and glutamatergic neurodegeneration [PDF]
, 2018 Mutations in Cu/Zn superoxide dismutase 1 (SOD1) lead to Amyotrophic Lateral Sclerosis (ALS), a neurodegenerative disease that disproportionately affects glutamatergic and cholinergic motor neurons.
Baskoylu, Saba N +10 more
core +3 more sources
CSF Monoamine Metabolites and Cognitive Trajectory in Early Parkinson's Disease
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Background Imaging and postmortem studies indicate that abnormalities in monoaminergic neurotransmission contribute to cognitive impairment in Parkinson's disease (PD). However, it remains uncertain if cerebrospinal fluid (CSF) monoamine metabolites can serve as biomarkers of cognitive decline in early PD.
Jing‐Yu Shao +7 more
wiley +1 more source
Angewandte Chemie, EarlyView.Schematic representation of M@E@CF nanosensors for detecting vesicular storage and release in cholinergic neurons and brain organoids. (A) Nano‐tip microelectrodes modification via molds fabricated through 3D printing. (B) the reaction mechanism for acetylcholine detection at the electrode interface.
Wanying Zhu +11 more
wiley +2 more sources
Frontiers in Neuroscience, 2021 Conserved transcription factors termed “terminal selectors” regulate neuronal sub-type specification and differentiation through combinatorial transcriptional regulation of terminal differentiation genes.
Sydney Popsuj, Alberto Stolfi
doaj +1 more source
Caveolin-3 differentially orchestrates cholinergic and serotonergic constriction of murine airways [PDF]
, 2018 The mechanisms of controlling airway smooth muscle (ASM) tone are of utmost clinical importance as inappropriate constriction is a hallmark in asthma and chronic obstructive pulmonary disease.
Hollenhorst, M. I. +7 more
core +2 more sources