Results 11 to 20 of about 146,455 (266)
Experimental Pharmacology in Transgenic Rodent Models of Alzheimer’s Disease
Frontiers in Pharmacology, 2019 This Mini Review discusses the merits and shortfalls of transgenic (tg) rodents modeling aspects of the human Alzheimer’s disease (AD) pathology and their application to evaluate experimental therapeutics.
A. Claudio Cuello +4 more
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Cyclosporine in Cholinergic Itch
Indian Dermatology Online Journal, 2022 Cholinergic itch is part of symptom complex that also includes cholinergic erythema and cholinergic urticaria. It mostly occurs during the winters among young adults. It is characterized by onset of severe itching or burning sensation all over body, mostly, on exposure to sunlight, warm atmosphere and in some cases after hot ...
Sumit Sehgal +5 more
openaire +3 more sources
Alzheimer’s Disease: Current and Future Treatments. A Review
International Journal of Medical Students, 2014 Alzheimer’s disease (AD) is a currently incurable neurodegenerative disorder whose treatment poses a big challenge. Proposed causes of AD include the cholinergic, amyloid and tau hypotheses.
Evelyn Chou
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Systematic review of the pharmacological properties of oligodendrocyte lineage
Frontiers in Cellular Neuroscience, 2016 OOligodendrogenesis and oligodendrocyte precursor maturation are essential processes during the course of central nervous system development, and lead to the myelination of axons.
Carla eMarinelli +4 more
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Physiological Reports, 2022 Vitronectin (VTN) is a glycoprotein enriched in the blood and activates integrin receptors. VTN blood levels increase only in female mice 24 h after an ischemic stroke and exacerbate brain injury through IL‐6‐driven inflammation, but the VTN induction ...
Matthew P. Keasey +3 more
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Neural regulation of ILC2s in allergic airway inflammation
Frontiers in Allergy, 2023 The sympathetic nervous system (SNS) and parasympathetic nervous system (PNS) regulate the effector functions of group 2 innate lymphoid cells (ILC2s) through β2 adrenergic receptor (ADRB2) and nicotinic/muscarinic cholinergic receptor signaling ...
Christopher M. Thomas +3 more
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Frontiers in Molecular Neuroscience, 2017 Alzheimer’s disease (AD) is a common age-related neurodegenerative disorder that is characterized by progressive cognitive decline. The deficits in cognition and attentional processing that are observed clinically in AD are linked to impaired function of
Leah K. Cuddy +7 more
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The Mesoscopic Connectome of the Cholinergic Pontomesencephalic Tegmentum
Frontiers in Neuroanatomy, 2022 The pontomesencephalic tegmentum, comprising the pedunculopontine nucleus and laterodorsal tegmental nucleus, is involved in various functions via complex connections; however, the organizational structure of these circuits in the whole brain is not ...
Peilin Zhao +9 more
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Loss of Sympathetic Nerves in Spleens from Patients with End Stage Sepsis
Frontiers in Immunology, 2017 The spleen is an important site for central regulation of immune function by noradrenergic sympathetic nerves, but little is known about this major region of neuroimmune communication in humans.
Donald B. Hoover +7 more
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An essential role of acetylcholine-glutamate synergy at habenular synapses in nicotine dependence
eLife, 2015 A great deal of interest has been focused recently on the habenula and its critical role in aversion, negative-reward and drug dependence. Using a conditional mouse model of the ACh-synthesizing enzyme choline acetyltransferase (Chat), we report that ...
Silke Frahm +5 more
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