Results 81 to 90 of about 285,894 (338)
Forebrain Cholinergic Signaling: Wired and Phasic, Not Tonic, and Causing Behavior
Conceptualizations of cholinergic signaling as primarily spatially diffuse and slow-acting are based largely on measures of extracellular brain ACh levels that require several minutes to generate a single data point.
M. Sarter, C. Lustig
semanticscholar +1 more source
Effects of selctive lesions of the nucleus basalis magnocellularis on working memory in rats. [PDF]
The nucleus basalis magnocellularis (NBM) of the rat brain is analogous to the nucleus basalis of Meynert found in humans. Alzheimer's disease patients have working memory impairments, which may be attributable to damage to the basal nucleus of Meynert ...
Noble, Michelle Marie
core +1 more source
Immunohistochemical staining for tyrosine hydroxylase reveals the neurons forming the locus coeruleus complex in the pontine region of the brain of the Congo gray parrot. The appearance and parcellation of the locus coeruleus complex in birds shows many similarities, but also differences to that observed in mammals.
Pedzisai Mazengenya, Paul R. Manger
wiley +1 more source
Generation of Choline for Acetylcholine Synthesis by Phospholipase D Isoforms [PDF]
DEDICATION: This article is dedicated to the memory of Sue Kim Hanson, a graduate student in the department of Pathology and Laboratory Medicine at Boston University School of Medicine, who perished in the terrorist attacks of September 11, 2001 ...
Blusztajn, Jan Krzysztof+2 more
core +3 more sources
Abstract Autonomic nerves are crucial in cardiac function and pathology. However, data on the distribution of cholinergic and noradrenergic nerves in normal and pathologic human hearts is lacking. Nonfailing donor hearts were pressure‐perfusion fixed, imaged, and dissected. Left ventricular cardiomyopathy samples were also obtained.
Peter Hanna+15 more
wiley +1 more source
Systematic review of the pharmacological properties of oligodendrocyte lineage
OOligodendrogenesis and oligodendrocyte precursor maturation are essential processes during the course of central nervous system development, and lead to the myelination of axons.
Carla eMarinelli+4 more
doaj +1 more source
Adaptive short‐term associative conditioning in the pancreatic β‐cell
This study associates cholinergic stimulation of the pancreatic β‐cell electrical activity with a short‐term memory phenomenon. Glucose pulses applied to a basal glucose concentration induce depolarizing waves which are used to estimate the evolution of ...
Juan V. Sanchez‐Andres+2 more
doaj +1 more source
The Mesoscopic Connectome of the Cholinergic Pontomesencephalic Tegmentum
The pontomesencephalic tegmentum, comprising the pedunculopontine nucleus and laterodorsal tegmental nucleus, is involved in various functions via complex connections; however, the organizational structure of these circuits in the whole brain is not ...
Peilin Zhao+9 more
doaj +1 more source
Physiology and immunology of the cholinergic antiinflammatory pathway.
Cytokine production by the immune system contributes importantly to both health and disease. The nervous system, via an inflammatory reflex of the vagus nerve, can inhibit cytokine release and thereby prevent tissue injury and death.
K. Tracey
semanticscholar +1 more source
Objective Systemic sclerosis (SSc) is a rare but severe autoimmune disease characterized by immune dysregulation, fibrosis, and vasculopathy. Although previous studies have highlighted the presence of functional autoantibodies targeting the angiotensin II receptor type 1 (AT1) and endothelin‐1 type A receptor (ETAR), leading to autoantibody‐mediated ...
Wieke M. van Oostveen+8 more
wiley +1 more source