Results 201 to 210 of about 85,202 (263)

Accelerated neurodegeneration of basal forebrain cholinergic neurons in HIV-1 gp120 transgenic mice: Critical role of the p75 neurotrophin receptor. [PDF]

Brain Behav Immun
Speidell A, Agbey C, Mocchetti I.
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Acetylcholinesterase and the cholinergic neuron

Life Sciences, 1979
Abstract While the distribution of AChE in the central nervous system remains largely unexplained, neurons with very high levels of AChE are frequently identified as cholinergic, and cholinergic neurons always have high levels of AChE. This supports the utility of the empirical rule, that identification of cholinergic neurons requires demonstration ...
J, Lehmann, H C, Fibiger
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Distribution of AChE in cholinergic and non-cholinergic neurons

Brain Research, 1981
Intracellular and surface acetylcholinesterase activities were determined for individual cholinergic and non-cholinergic neurons dissected from the central nervous system of the leech. Echothiophate pretreatment was used to inhibit selectively extracellular enzyme.
exaly   +3 more sources

Choline and Cholinergic Neurons

Science, 1983
Mammalian neurons can synthesize choline by methylating phosphatidylethanolamine and hydrolyzing the resulting phosphatidylcholine. This process is stimulated by catecholamines. The phosphatidylethanolamine is synthesized in part from phosphatidylserine; hence the amino acids methionine (acting after conversion to S
J K, Blusztajn, R J, Wurtman
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From the cholinergic gene locus to the cholinergic neuron

Journal of Physiology-Paris, 1998
The cholinergic gene locus (CGL) was first identified in 1994 as the site (human chromosome 10q11.2) at which choline acetyltransferase and a functional vesicular acetylcholine transporter are co-localized. Here, we present recent neuroanatomical, developmental, and evolutionary insights into the chemical coding of cholinergic neurotransmission that ...
E, Weihe, M K, Schäfer, B, Schütz, M, Anlauf, C, Depboylu, C, Brett, L, Chen, L E, Eiden   +7 more
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Mesopontine cholinergic and non-cholinergic neurons in schizophrenia

Neuroscience, 1999
Mesopontine cholinergic neurons influence midbrain dopaminergic neurons, and thalamic and cerebellar structures which have been implicated in the neuroanatomy of schizophrenia. It has been reported that there are approximately twice as many mesopontine cholinergic neurons in schizophrenics than in normals, using nicotinomide adenosine dinucleotide ...
D C, German, K F, Manaye, D, Wu, L B, Hersh, R M, Zweig   +4 more
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β-Amyloid and Cholinergic Neurons

Neurochemical Research, 2003
It is generally accepted that the crucial events in the pathogeny of Alzheimer's disease (AD) are the increased accumulation of amyloidogenic peptides derived from amyloid precursor protein and the harmful actions of these peptides on neurons, which bring about neurodegeneration. The enhanced beta-amyloid accumulation is known to be caused by mutations
Vladimír, Dolezal, Jana, Kasparová
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The localization of central cholinergic neurons

Progress in Neuro-Psychopharmacology and Biological Psychiatry, 1986
Over the past decade our understanding of the localization of central cholinergic neurons has greatly increased. Interest in these systems has also intensified due to the involvement of cholinergic mechanisms in Alzheimer's disease. The distribution of central cholinergic neurons is reviewed, focusing on recent work in experimental animals.
S R, Vincent, K, Satoh, H C, Fibiger
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Dopaminergic Dependency of Cholinergic Pallidal Neurons

Neuroscience, 2023
We employed the whole-cell patch-clamp method and ChAT-Cre mice to study the electrophysiological attributes of cholinergic neurons in the external globus pallidus. Most neurons were inactive, although approximately 20% displayed spontaneous firing, including burst firing.
Janintzitzic López-Niño, Montserrat Padilla-Orozco, Aidán Ortega, Verónica Alejandra Cáceres-Chávez, Dagoberto Tapia, Antonio Laville, Elvira Galarraga, José Bargas   +7 more
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Cholinergic neurons in the human retina

Experimental Eye Research, 1987
Choline acetyltransferase (ChAT)-like immunoreactivity in the human retina can be demonstrated using a polyclonal antiserum to ChAT isolated from chick brain. There is a population of ChAT-like immunoreactive cells along both margins of the inner plexiform layer (IPL).
J B, Hutchins, J G, Hollyfield
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