Results 111 to 120 of about 2,475,404 (303)

Changes in immunoreactivity of muscarinic cholinergic receptors and protein kinase C in the hippocampus of amygdala-kindled rats

, 1990
Hans Beldhuis, Eddy A. van der Zee, B Bohus   +2 more
openalex   +2 more sources

Altered Hippocampal Transcriptomic Profile Reveals Cognitive Impairment in Young Metabolically Obese, Normal‐Weight Rats, Prevented by Perinatal Leptin Intake

Molecular Nutrition &Food Research, EarlyView.
Early‐life exposure of rats to high‐fat‐isocaloric diet leads to metabolically obese, normal‐weight phenotype, and impaired cognition. Hippocampal transcriptomic analysis reveals disruption in pathways linked to obesity and cognitive decline, which is mitigated by perinatal leptin supplementation. PBMC share common altered genes with hippocampus, which
Carmen García‐Ruano, Andrea Costa, Andreu Palou, Paula Oliver   +3 more
wiley   +1 more source

Libidibia ferreaMature Seeds Promote Antinociceptive Effect by Peripheral and Central Pathway: Possible Involvement of Opioid and Cholinergic Receptors

, 2014
Luis Armando Sawada, Vanessa Sâmia da Conçeição Monteiro, Guilherme Rodrigues Rabelo, Germana Bueno Dias, Maura Da Cunha, José Luíz Martins do Nascimento, Gilmara de Nazareth Tavares Bastos   +6 more
openalex   +1 more source

Efficient analysis of toxicity and mechanisms of isoflurane on postoperative delirium by network toxicology and molecular docking

Neuroprotection, EarlyView.
Abstract Postoperative delirium (POD), a prevalent neurological complication in older surgical patients, adversely affects recovery. Isoflurane, a common inhalational anesthetic, exhibits neurotoxic potential, but its role in POD pathogenesis remains unclear.
Zhiming Dai, Qing Nan, Menglu Xu, Hongbao Li   +3 more
wiley   +1 more source

Promoting activity of (α4)₃(β2)₂ nicotinic cholinergic receptors reduces ethanol consumption. [PDF]

Neuropsychopharmacology, 2020
Wang J, Blasio A, Chapman HL, Doebelin C, Liaw V, Kuryatov A, Giovanetti SM, Lindstrom J, Lin L, Cameron MD, Kamenecka TM, Pomrenze MB, Messing RO.   +12 more
europepmc   +1 more source

The mechanism by which adenosine and cholinergic agents reduce contractility in rat myocardium. Correlation with cyclic adenosine monophosphate and receptor densities. [PDF]

, 1985
Joel Linden, C E Hollen, Amrat Patel
openalex   +1 more source

Involvement of Striatal Cholinergic Interneurons and M1 and M4 Muscarinic Receptors in Motor Symptoms of Parkinson's Disease

Journal of Neuroscience, 2016
Samira Ztaou, N. Maurice, J. Camon, G. Guiraudie-Capraz, L. Kerkerian-Le Goff, C. Beurrier, M. Liberge, M. Amalric   +7 more
semanticscholar   +1 more source

Design, Synthesis, In Silico Absorption, Distribution, Metabolism, and Elimination and Molecular Docking Studies of Thiazole‐Based Furan Derivatives, and Their Biological Evaluation for Alzheimer Disease Therapy

ChemistryOpen, EarlyView.
GA: Oxidative stress plays a critical role in Alzheimer's disease (AD) by promoting Aβ plaque accumulation and tau pathology, accelerating neurodegeneration. Elevated reactive oxygen species contribute to cognitive decline through extensive oxidative damage.
Abdüllatif Karakaya, Ulviye Acar Çevik, Betül Kaya, Bilge Çiftçi, Adem Necip, Mesut Işık, Şükrü Beydemir, Yusuf Özkay, Zafer Asım Kaplancıklı   +8 more
wiley   +1 more source

Nipocalimab Dose Selection in Generalized Myasthenia Gravis

CPT: Pharmacometrics &Systems Pharmacology, EarlyView.
Model‐Informed Nipocalimab Dose Selection for Generalized Myasthenia Gravis. ABSTRACT Nipocalimab is a fully human immunoglobulin G (IgG)1 monoclonal antibody (mAb) designed to selectively block the IgG binding site of neonatal fragment crystallizable receptor (FcRn) to inhibit IgG recycling and decrease circulating IgG, including pathogenic IgG ...
Belén Valenzuela, Martine Neyens, Yaowei Zhu, Sindhu Ramchandren, Anne‐Gaëlle Dosne, Jocelyn H. Leu, Ruben Faelens, Leona E. Ling, Juan‐José Pérez‐Ruixo   +8 more
wiley   +1 more source

Differential contribution of cholinergic and glutamatergic receptors to attentional modulation in V1

, 2012
Alexander Thiele, J. Herreo, Alwin Gieselmann   +2 more
openalex   +1 more source