Results 11 to 20 of about 140,233 (301)

Brain muscarinic cholinergic receptors in Huntington's disease [PDF]

, 1992
Muscarinic cholinergic receptors and choline acetyltransferase (ChAT) activity were studied in postmortem brain tissue from patients with Huntington's disease and matched control subjects.
Agid, Y., Javoy-Agid, F., Jenner, P., Lange, Klaus W., Marsden, C. D.   +4 more
core   +1 more source

Interactions between the neuromodulatory systems and the amygdala: exploratory survey using the Allen Mouse Brain Atlas. [PDF]

, 2013
Neuromodulatory systems originate in nuclei localized in the subcortical region of the brain and control fundamental behaviors by interacting with many areas of the central nervous system.
Krichmar, Jeffrey L, Zaldivar, Andrew
core   +1 more source

Alpha9 nicotinic acetylcholine receptors and the treatment of pain [PDF]

, 2009
Chronic pain is a vexing worldwide problem that causes substantial disability and consumes significant medical resources. Although there are numerous analgesic medications, these work through a small set of molecular mechanisms.
Absalom, Nathan, Chebib, Mary, Elgoyhen, Ana Belen, McIntosh, J. Michael, Vincler, Michelle   +4 more
core   +1 more source

The nicotinic receptor of cochlear hair cells: A possible pharmacotherapeutic target? [PDF]

, 2009
Mechanosensory hair cells of the organ of Corti transmit information regarding sound to the central nervous system by way of peripheral afferent neurons.
Elgoyhen, Ana Belen, Fuchs, Paul A., Katz, Eleonora   +2 more
core   +1 more source

Cholinergic Regulation of Hippocampal Theta Rhythm

Biomedicines, 2022
Cholinergic regulation of hippocampal theta rhythm has been proposed as one of the central mechanisms underlying hippocampal functions including spatial memory encoding.
Zhenglin Gu, Jerrel L. Yakel
doaj   +1 more source

The involvement of cholinergic neurons in the spreading of tau pathology

Frontiers in Neurology, 2013
Long time ago, it was described the selective loss of cholinergic neurons during the development of Alzheimer disease. Recently, it has been suggested that tau protein may play a role in that loss of cholinergic neurons through a mechanism involving the ...
Diana eSimon, Diana eSimon, Felix eHernandez, Felix eHernandez, Jesus eAvila, Jesus eAvila   +5 more
doaj   +1 more source

Cholinergic suppression: A postsynaptic mechanism of long-term associative learning [PDF]

, 1986
Food avoidance learning in the mollusc Pleurobranchaea entails reduction in the responsiveness of key brain interneurons in the feeding neural circuitry, the paracerebral feeding command interneurons (PCNs), to the neurotransmitter acetylcholine (AcCho).
Davis, W. Jackson, Kovac, Mark P., Matera, Eugene M., McCormack, Kenneth J., Morielli, Anthony D., Shrum, Richard G.   +5 more
core   +2 more sources

Non-neuronal regulation and repertoire of cholinergic receptors in organs

Biomolecular Concepts, 2010
Many studies on the cholinergic pathway have indicated that cholinergic receptors, which are widely expressed in various cells, play an important role in all body organs.
Sato Tsuyoshi, Chida Dai, Iwata Takanori, Usui Michihiko, Hatori Kouki, Abe Takahiro, Takeda Shu, Yoda Tetsuya   +7 more
doaj   +1 more source

Repurposing Pilocarpine Hydrochloride for Treatment of Candida albicans Infections

mSphere, 2019
Acetylcholine modulates the virulence of Candida albicans and regulates an appropriate immune response to infection in a Galleria mellonella infection model. Indeed, the evidence suggests that C.
Christopher Nile, Monica Falleni, Daniela Cirasola, Abeer Alghamdi, Oliver F. Anderson, Christopher Delaney, Gordon Ramage, Emerenziana Ottaviano, Delfina Tosi, Gaetano Bulfamante, Giulia Morace, Elisa Borghi   +11 more
doaj   +1 more source

Endogenous cholinergic inputs and local circuit mechanisms govern the phasic mesolimbic dopamine response to nicotine [PDF]

, 2013
Nicotine exerts its reinforcing action by stimulating nicotinic acetylcholine receptors (nAChRs) and boosting dopamine (DA) output from the ventral tegmental area (VTA).
A Taly, AA Grace, AJ Yu, AO Komendantov, AR Tapper, B Buisson, B Katz, Boris Gutkin, C Lüscher, C Shelley, CP Fenster, DB Carr, E Lichtenstein, E Sher, EJ Nestler, F Marti, FE Pontieri, G Di Chiara, G Di Chiara, G Di Chiara, GL Forster, HD Mansvelder, HD Mansvelder, HR Wilson, IW Jones, J Cornwall, J Grenhoff, JA Dani, Ja Dani, JB Eaton, JE Henningfield, JE Rose, JN Reynolds, JP Changeux, JP Changeux, JP Changeux, JR Clements, JR Wooltorton, K Chergui, Karl J. Friston, KG Paradiso, LE Chavez-Noriega, M Gao, M Garzón, M Graupner, M Mameli-Engvall, M Wu, MG Lacey, Michael Graupner, MJ Christie, MR Picciotto, MR Picciotto, N Champtiaux, P Dayan, PW Kalivas, R Exley, R Giniatullin, R Klink, R Nashmi, Reinoud Maex, RL Papke, S Erhardt, S Ikemoto, S Tolu, SA Oakman, SC Steffensen, SR Grady, SR Sesack, SW Johnson, SW Johnson, TC Jhou, V David, V Gerzanich, V Gerzanich, VI Pidoplichko, WA Corrigall, X Peng, ZM Fagen, ZY Tong   +78 more
core   +6 more sources