Central Cholinergic Nervous System and Cholinergic Agents [PDF]
Acta Medica, 1998 Central cholinergic nervous system play important role in many physiological and behavioral functions in humans. The activity of the cholinergic nervous system depends upon the production and fate of acetylcholine and all compounds influenced its ...
Jiří Patočka
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Alzheimer's disease: Targeting the Cholinergic System [PDF]
Current Neuropharmacology, 2016 Acetylcholine (ACh) has a crucial role in the peripheral and central nervous systems. The enzyme choline acetyltransferase (ChAT) is responsible for synthesizing ACh from acetyl-CoA and choline in the cytoplasm and the vesicular acetylcholine transporter (VAChT) uptakes the neurotransmitter into synaptic vesicles.
Talita H. Ferreira‐Vieira +3 more
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Dissociable roles for the striatal cholinergic system in different flexibility contexts [PDF]
IBRO Neuroscience Reports, 2022 The production of behavioural flexibility requires the coordination and integration of information from across the brain, by the dorsal striatum. In particular, the striatal cholinergic system is thought to be important for the modulation of striatal ...
Brendan Williams, Anastasia Christakou
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Characterization of social behavior in young and middle-aged ChAT-IRES-Cre mouse.
PLoS ONE, 2022 The cholinergic system is an important modulator of brain processes. It contributes to the regulation of several cognitive functions and emotional states, hence altering behaviors.
Cyril Lhopitallier +6 more
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Characterization of Cholinergic System Dysregulation in the McGill‐R955‐hTau Rat Model of Human‐Like Tauopathy [PDF]
Alzheimers DementBonomo Q, Carmo S, Cuello C.
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The cholinergic system in the pathophysiology and treatment of Alzheimer’s disease [PDF]
Brain, 2018 Harald Hampel +2 more
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Cholinergic system changes in Parkinson's disease: emerging therapeutic approaches [PDF]
Lancet Neurology, The, 2022 Nicolaas I Bohnen +2 more
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Non-neuronal cholinergic system in the heart influences its homeostasis and an extra-cardiac site, the blood-brain barrier. [PDF]
Front Cardiovasc MedKakinuma Y.
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Cholinergic System and Its Therapeutic Importance in Inflammation and Autoimmunity
Frontiers in Immunology, 2021 Neurological and immunological signals constitute an extensive regulatory network in our body that maintains physiology and homeostasis. The cholinergic system plays a significant role in neuroimmune communication, transmitting information regarding the ...
Namrita Halder, Girdhari Lal
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Cellular birthdate predicts laminar and regional cholinergic projection topography in the forebrain
eLife, 2020 The basal forebrain cholinergic system projects broadly throughout the cortex and constitutes a critical source of neuromodulation for arousal and attention. Traditionally, this system was thought to function diffusely.
Kathryn C Allaway +7 more
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