Omicron SARS-CoV-2 Spike-1 Protein’s Decreased Binding Affinity to α7nAChr: Implications for Autonomic Dysregulation of the Parasympathetic Nervous System and the Cholinergic Anti-Inflammatory Pathway—An In Silico Analysis [PDF]
, 2022 Domiziano Doria +4 more
openalex +1 more source
Intratumoral Nerve Phased Development: A Promising Therapeutic Target
Medicine Bulletin, EarlyView.ABSTRACT The nervous system has emerged as a critical regulator of tumor biology, engaging in dynamic crosstalk with cancer cells. Although the protumorigenic role of innervation is well established, increasing attention is now directed toward reciprocal influences—how tumors actively shape and remodel local nerve networks within the tumor ...
Xiangxian Che +3 more
wiley +1 more source
The Brain of the Archerfish Toxotes chatareus: A Nissl-Based Neuroanatomical Atlas and Catecholaminergic/Cholinergic Systems [PDF]
, 2016 Naomi Karoubi +2 more
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Basal Forebrain Volume Predicts Disease Conversion in Prodromal Synucleinopathy
Movement Disorders Clinical Practice, EarlyView.Abstract Background Isolated rapid eye movement sleep behavior disorder (iRBD) is a prodromal stage of Parkinson's disease (PD) and dementia with Lewy bodies (DLB). The basal forebrain (BF), a key cholinergic structure, is a site of known pathology in later stages of Lewy body disorders.
Lachlan Churchill +5 more
wiley +1 more source
Functional neurochemical imaging of the human striatal cholinergic system during reversal learning [PDF]
, 2017 Tiffany Bell +3 more
openalex +1 more source
Movement Disorders Clinical Practice, EarlyView.This study demonstrated significant treatment efficacy and safety of incobotulinumtoxinA injection in Japanese patients with chronic sialorrhea caused by Parkinson's disease and other neurological conditions. Suppression of salivary secretion and improvement in drooling symptoms were also observed throughout 48 weeks.
Nobutaka Hattori +15 more
wiley +1 more source
Determination of transmitter function by neuronal activity [PDF]
, 1977 The role of neuronal activity in the determination of transmitter function was studied in cultures of dissociated sympathetic neurons from newborn rat superior cervical ganglia.
Campenot, Robert B. +2 more
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Thalamic Deep Brain Stimulation for Dystonic Head Tremor: A Long‐Term Study of 18 Patients
Movement Disorders Clinical Practice, EarlyView.Abstract Background Dystonic head tremor is a particular manifestation of dystonia, which is difficult to treat. Although deep brain stimulation (DBS) of the globus pallidus internus has been established as a treatment for different phenotypes of dystonia, its role in dystonic tremor has been debated.
Johanna M. Nagel +7 more
wiley +1 more source
Mediators of Inflammation, 2014 Nonneuronal cholinergic system plays a primary role in maintaining homeostasis. It has been proved that endogenous neuronal acetylcholine (ACh) could play an anti-inflammatory role, and exogenous cholinergic agonists could weaken macrophages inflammatory
Yi Lv +6 more
doaj +1 more source
Movement Disorders Clinical Practice, EarlyView.Abstract Background Pregnancy after a Parkinson's diagnosis presents complex challenges. Due to the paucity of literature, there is no evidence‐based guidelines and protocols for preconception care, management of pregnancy, childbirth and the postpartum period in women with early‐onset Parkinson's disease (PD).
Alexander C. Lehn +18 more
wiley +1 more source