The M-current contributes to high threshold membrane potential oscillations in a cell type-specific way in the pedunculopontine nucleus of mice. [PDF]
Frontiers in Cellular Neuroscience, 2015 The pedunculopontine nucleus is known as a cholinergic nucleus of the reticular activating system, participating in regulation of sleep and wakefulness. Besides cholinergic neurons, it consists of GABAergic and glutamatergic neurons as well. According to
Bordas, Csilla +2 more
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PET Imaging of Perceptual Learning-Induced Changes in the Aged Rodent Cholinergic System [PDF]
Frontiers in Neuroscience, 2020 The cholinergic system enhances attention and gates plasticity, making it a major regulator of adult learning. With aging, however, progressive degeneration of the cholinergic system impairs both the acquisition of new skills and functional recovery ...
J. Miguel Cisneros-Franco +9 more
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Characterization of social behavior in young and middle-aged ChAT-IRES-Cre mouse.
PLoS ONE, 2022 The cholinergic system is an important modulator of brain processes. It contributes to the regulation of several cognitive functions and emotional states, hence altering behaviors.
Cyril Lhopitallier +6 more
doaj +2 more sources
Dissociable roles for the striatal cholinergic system in different flexibility contexts. [PDF]
IBRO Neurosci Rep, 2022 The production of behavioural flexibility requires the coordination and integration of information from across the brain, by the dorsal striatum. In particular, the striatal cholinergic system is thought to be important for the modulation of striatal ...
Williams B, Christakou A.
europepmc +2 more sources
Cholinergic System and Its Therapeutic Importance in Inflammation and Autoimmunity
Frontiers in Immunology, 2021 Neurological and immunological signals constitute an extensive regulatory network in our body that maintains physiology and homeostasis. The cholinergic system plays a significant role in neuroimmune communication, transmitting information regarding the ...
Namrita Halder, Girdhari Lal
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Cellular birthdate predicts laminar and regional cholinergic projection topography in the forebrain
eLife, 2020 The basal forebrain cholinergic system projects broadly throughout the cortex and constitutes a critical source of neuromodulation for arousal and attention. Traditionally, this system was thought to function diffusely.
Kathryn C Allaway +7 more
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Scientific Reports, 2021 Social behaviour is a complex construct that is reported to include several components of social approach, interaction and recognition memory. Alzheimer’s disease (AD) is mainly characterized by progressive dementia and is accompanied by cognitive ...
Kana Okada +5 more
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ACETYLCHOLINE AND ITS SYNTHESIZING ENZYME CHOLINE ACETYLTRANSPHERASE IN THE ENTERIC NERVOUS SYSTEM [PDF]
Journal of IMAB, 2022 The enteric nervous system is the largest and most complex division of the peripheral nervous system. Located in the wall of the gastrointestinal tract, it is a regulatory and coordination unit of the nervous system.
Desislava M. Marinova +5 more
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A Cholinergic Synaptically Triggered Event Participates in the Generation of Persistent Activity Necessary for Eye Fixation [PDF]
, 2004 An exciting topic regarding integrative properties of the nervous system is how transient motor commands or brief sensory stimuli are able to evoke persistent neuronal changes, mainly as a sustained, tonic action potential firing.
Alvarado, JC +5 more
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Acetylcholine and spinal locomotor networks: The insider
Physiological Reports, 2021 This article aims to review studies that have investigated the role of neurons that use the transmitter acetylcholine (ACh) in controlling the operation of locomotor neural networks within the spinal cord. This cholinergic system has the particularity of
Théo Mille +3 more
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