Results 121 to 130 of about 46,746 (260)

Therapeutic Targeting of the α7 Nicotinic Receptor: Challenges and Prospects for Cognitive Improvement in Alzheimer's and Schizophrenia

Basic &Clinical Pharmacology &Toxicology, Volume 137, Issue 1, July 2025.
ABSTRACT The α7 nicotinic acetylcholine receptor (α7 nAChR) has emerged as a key target for treating cognitive dysfunction in neurological disorders such as Alzheimer's disease (AD) and schizophrenia. α7 nAChRs play essential roles in neurotransmission, neuroinflammation and synaptic plasticity, not only in neurons but also in glial cells, where they ...
Janus H. Magnussen
wiley   +1 more source

Two selective inhibitors of cholinesterase [PDF]

, 1953
L. Austin, W.K. Berry
openalex   +1 more source

Quantification of Methylene Blue and Evaluation of Its Pharmacokinetics in ICR Mice by Liquid Chromatography‐Quadrupole Time‐of‐Flight Mass Spectrometry Using Difluoroacetic Acid

Biomedical Chromatography, Volume 39, Issue 6, June 2025.
ABSTRACT Methylene blue (MB), a phenothiazine derivative, is currently under clinical trials for Alzheimer's disease (AD) due to its potential to inhibit tau aggregation, a key pathological process in AD. In this study, we developed and qualified a rapid and reliable liquid chromatography‐quadrupole time‐of‐flight mass spectrometry (LC‐qTOF‐MS) method ...
Seo‐jin Park, Juwon Lee, Sangsoo Hwang, Jeong‐hyeon Lim, Hyunjin Cho, Young G. Shin   +5 more
wiley   +1 more source

The inhibition of erythrocyte cholinesterase by tri-esters of phosphoric acid. 1. Diethyl p-nitrophenyl phosphate (E 600) and analogues [PDF]

, 1952
W. N. Aldridge, A. N. Davison
openalex   +1 more source

Light Sensitivity in Myasthenia Gravis: Clinical Characteristics and Impact on Quality of Life

Muscle &Nerve, Volume 71, Issue 6, Page 1081-1085, June 2025.
ABSTRACT Introduction/Aims Light sensitivity is occasionally reported in myasthenia gravis patients, yet its prevalence, clinical characteristics, and impact on disease severity and quality of life remain insufficiently explored. This study aimed to evaluate the frequency, clinical characteristics, and the correlation of light sensitivity with ...
Eleonora Sabatelli, Luca Bonagura, Silvia Falso, Sofia Marini, Claudia Papi, Lucia Campetella, Michela Myriam De Maio, Raffaele Iorio   +7 more
wiley   +1 more source

The Effect of Diazinon on Cholinesterase Activity in Plasma and Erythrocytes of Male and Female Rats and the Protective Role of Vitamin E

پزشکی بالینی ابن سینا, 2015
Introduction & Objective: Diazinon (DZN) is an organophosphate insecticide that one of the mechanisms of toxicity is the inhibition of cholinesterase.
Fatemeh Rahimi Anbarkeh, Mohammadreza Nikravesh, Mahdi Jalali, Hamidreza Sadeghnia, Zeynab Sargazi   +4 more
doaj  

Underdiagnosis of dementia in residents of residential aged care services: A scoping review

Australasian Journal on Ageing, Volume 44, Issue 2, June 2025.
Abstract Objective Dementia is a leading cause of disability, dependence and death worldwide. Timely diagnosis and management of dementia are essential in the community and residential aged care services (RACS) or nursing homes. Underdiagnosis of dementia in RACS may negatively impact the quality of care, resulting in adverse health outcomes. Hence the
Reena Tewari, Ronaldo D. Piovezan, Agathe Daria Jadczak, Renuka Visvanathan   +3 more
wiley   +1 more source

Cholinesterase in the Skin of the Rat, Dog, Cat, Guinea Pig and Rabbit11From the Section of Dermatology and the Section of Pathologic Anatomy, Mayo Clinic and Mayo Foundation, Rochester, Minnesota. This study was supported in part by Public Health Service Grant No. B-1755 (C1)

, 1959
R.K. Winkelmann, Robert W. Schmit
openalex   +1 more source

A Short Story Changed How I Care for Persons Living With Dementia

Journal of the American Geriatrics Society, EarlyView.
Jason Karlawish
wiley   +1 more source

The mechanisms of motor end‐plate depolarization due to a cholinesterase‐inhibiting drug

, 1954
W. W. Douglas, W. D. M. Paton
openalex   +2 more sources