Results 11 to 20 of about 90,058 (326)

Effects of Standard Treatment Alone Versus Standard Treatment plus Plasmapheresis on the Levels of Serum Pseudocholinesterase and Erythrocyte Acetylcholinesterase in Critically Patients with Organophosphate Poisoning: Randomized Controlled, Open-label, Clinical Trial

Hitit Medical Journal, 2023
Objective: Organophosphates are the insecticides commonly used worldwide. Inadequate treatment in organophosphates poisoning increases morbidity, and mortality.
Muhammet Güven, Şahin Temel, Ramazan Coşkun, Murat Sungur, Okhan Akdur, Cevat Yazıcı, Kürşat Gündoğan, Hilal Sipahioğlu, Gülten Can Sezgin   +8 more
doaj   +1 more source

Correlation and prognostic significance of serum amylase, serum lipase, and plasma cholinesterase in acute organophosphorus poisoning

Journal of Family Medicine and Primary Care, 2020
Background: Organophosphorus (OP) are substances that are originally produced by the reaction of alcohols and phosphoric acid. These OP compounds are the main components of herbicides, pesticides, and insecticides.
Ajit Dungdung, Abhinav Kumar, Bindey Kumar, Mukul Preetam, Ruth K Tara, Md K Saba   +5 more
doaj   +1 more source

An investigation of acute effects at various doses of malathion on glucose homeostasis and insulin resistance in rat liver, pancreas and serum [PDF]

, 2020
Objective. This study investigates acute effects of various doses of Malathion on glucose homeostasis and insulin resistance in rat. Methods. Rats were randomly divided into four groups of 6 animals each. Corn oil was given orally to Group 1.
Ekremoğlu, Murat, Pasaoğlu, Hatice, Pasaoğlu, Özge Tuğce, Severcan, Çınar, Şen, Bayram   +4 more
core   +3 more sources

Mass spectrometry in ocular drug research

Mass Spectrometry Reviews, EarlyView., 2023
Abstract Mass spectrometry (MS) has been proven as an excellent tool in ocular drug research allowing analyzes from small samples and low concentrations. This review begins with a short introduction to eye physiology and ocular pharmacokinetics and the relevance of advancing ophthalmic treatments.
Eva M. del Amo, Kati‐Sisko Vellonen, Arto Urtti, Tetsuya Terasaki, Anam Hammid, Paavo Honkakoski, Seppo Auriola   +6 more
wiley   +1 more source

Prognostic Significance of Serum Cholinesterase Level in Patients With Acute Decompensated Heart Failure With Preserved Ejection Fraction: Insights From the PURSUIT‐HFpEF Registry

Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, 2020
Background Malnutrition is one of the most important comorbidities in patients with heart failure with preserved ejection fraction. We recently reported the prognostic significance of serum cholinesterase level and superior predictive power of ...
Masahiro Seo, Takahisa Yamada, Shunsuke Tamaki, Shungo Hikoso, Yoshio Yasumura, Yoshiharu Higuchi, Yusuke Nakagawa, Masaaki Uematsu, Haruhiko Abe, Hisakazu Fuji, Toshiaki Mano, Daisaku Nakatani, Masatake Fukunami, Yasushi Sakata   +13 more
doaj   +1 more source

In vitro inhibition of human blood cholinesterases and protection against chlorpyriphos (organophosphate) by weak anticholinesterase drugs [PDF]

المجلة العراقية للصيدلة, 2011
In vitro inhibition of human plasma and erythrocyte cholinesterase activities by the strong cholinesterase inhibitor chlorpyriphos (organophosphate) and the weak cholinesterase inhibitors (donepezil, metoclopramide, and diphenhydramine) in different ...
Ahmed A.J. Mahmood
doaj   +1 more source

Recent developments in the design and synthesis of benzylpyridinium salts: Mimicking donepezil hydrochloride in the treatment of Alzheimer’s disease

Frontiers in Chemistry, 2022
Background: Alzheimer’s disease (AD) is an advanced and irreversible degenerative disease of the brain, recognized as the key reason for dementia among elderly people.
Saghi Sepehri, Saghi Sepehri, Mina Saeedi, Mina Saeedi, Bagher Larijani, Mohammad Mahdavi   +5 more
doaj   +1 more source

PON1 status does not influence cholinesterase activity in Egyptian agricultural workers exposed to chlorpyrifos. [PDF]

, 2012
Animal studies have shown that paraoxonase 1 (PON1) genotype can influence susceptibility to the organophosphorus pesticide chlorpyrifos (CPF). However, Monte Carlo analysis suggests that PON1 genotype may not affect CPF-related toxicity at low exposure ...
Bonner, Matthew R, Browne, Richard W, Crane, Alice L, Ellison, Corie A, Knaak, James B, Lein, Pamela J, Olson, James R   +6 more
core   +1 more source

Assessing Non-Invasive Liver Function in Patients With Intestinal Failure Receiving Total Parenteral Nutrition-Results From the Prospective PNLiver Trial [PDF]

, 2020
Liver abnormalities in intestinal failure (IF) patients receiving parenteral nutrition (PN) can progress undetected by standard laboratory tests to intestinal failure associated liver disease (IFALD). The aim of this longitudinal study is to evaluate the
Bednarsch, Jan, Blüthner, Elisabeth, Gerlach-Runge, Undine, Karber, Mirjam, Maasberg, Sebastian, Pape, Ulrich-Frank, Pascher, Andreas, Pevny, Sophie, Pratschke, Johann, Stockmann, Martin, Tacke, Frank   +10 more
core   +1 more source

Using Virtual AChE Homology Screening to Identify Small Molecules With the Ability to Inhibit Marine Biofouling

Frontiers in Marine Science, 2021
The search for effective yet environmentally friendly strategies to prevent marine biofouling is hampered by the large taxonomic diversity amongst fouling organisms and a lack of well-defined conserved molecular targets.
Homayon John Arabshahi, Tomaž Trobec, Valentin Foulon, Claire Hellio, Robert Frangež, Kristina Sepčić, Patrick Cahill, Johan Svenson   +7 more
doaj   +1 more source