Results 11 to 20 of about 46,746 (260)

Mass spectrometry in ocular drug research

open access: yesMass Spectrometry Reviews, EarlyView., 2023
Abstract Mass spectrometry (MS) has been proven as an excellent tool in ocular drug research allowing analyzes from small samples and low concentrations. This review begins with a short introduction to eye physiology and ocular pharmacokinetics and the relevance of advancing ophthalmic treatments.
Eva M. del Amo   +6 more
wiley   +1 more source

Studies on Cholinesterase

open access: bronzeThe Tohoku Journal of Experimental Medicine, 1951
S, OKINAKA   +5 more
  +8 more sources

Using Virtual AChE Homology Screening to Identify Small Molecules With the Ability to Inhibit Marine Biofouling

open access: yesFrontiers in Marine Science, 2021
The search for effective yet environmentally friendly strategies to prevent marine biofouling is hampered by the large taxonomic diversity amongst fouling organisms and a lack of well-defined conserved molecular targets.
Homayon John Arabshahi   +7 more
doaj   +1 more source

Evaluation of Cholinesterase Activities During in Vivo Intoxication Using an Electrochemical Sensor Strip – Correlation With Intoxication Symptoms

open access: yesSensors, 2009
Cholinesterase activity in blood of laboratory rats was monitored. Rats were intoxicated with paraoxon at dosis of 0 – 65 – 125 – 170 – 250 – 500 nmol. The 250 nmol dose was found to be the LD50.
Jana Zdarova-Karasova   +5 more
doaj   +1 more source

Integration of clinical demographics and routine laboratory analysis parameters for early prediction of gestational diabetes mellitus in the Chinese population

open access: yesFrontiers in Endocrinology, 2023
Gestational diabetes mellitus (GDM) is one of the most common complications in pregnancy, impairing both maternal and fetal health in short and long term. As early interventions are considered desirable to prevent GDM, this study aims to develop a simple-
Hesong Zhang   +8 more
doaj   +1 more source

Affordable Portable Platform for Classic Photometry and Low-Cost Determination of Cholinesterase Activity

open access: yesBiosensors, 2023
Excessive use of pesticides could potentially harm the environment for a long time. The reason for this is that the banned pesticide is still likely to be used incorrectly.
Ondřej Keresteš, Miroslav Pohanka
doaj   +1 more source

Opportunities for multiscale computational modelling of serotonergic drug effects in Alzheimer's disease [PDF]

open access: yes, 2020
Alzheimer's disease (AD) is an age-specific neurodegenerative disease that compromises cognitive functioning and impacts the quality of life of an individual. Pathologically, AD is characterised by abnormal accumulation of beta-amyloid (A$\beta$) and hyperphosphorylated tau protein.
arxiv   +1 more source

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