Results 31 to 40 of about 46,746 (260)
Molecules, 2021 Alkaloids are a class of secondary metabolites that can be derived from plants, fungi and marine sponges. They are widely known as a continuous source of medicine for the management of chronic disease including cancer, diabetes and neurodegenerative ...
Yew Rong Kong +5 more
doaj +1 more source
Sensors, 2009 A cholinesterase based biosensor was constructed in order to assess the effects of ionizing radiation on exposed AChE. Although the primary objective of the experiment was to investigate the effect of ionizing radiation on the activity of the biosensor ...
Miroslav Pohanka, Miroslav Koch
doaj +1 more source
The Cholinesterase Inhibitory Properties of Stephaniae Tetrandrae Radix
Molecules, 2020 Stephaniae tetrandrae radix (STR) is a commonly used traditional Chinese medicine in alleviating edema by inducing diuresis. In the clinic, STR extracts or its components are widely used in the treatment of edema, dysuria, and rheumatism for the ...
Xiang-Peng Kong +7 more
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Identification of New N-methyl-piperazine Chalcones as Dual MAO-B/AChE Inhibitors
Pharmaceuticals, 2023 Monoamine oxidase-B (MAO-B), acetylcholinesterase (AChE), and butyrylcholinesterase (BChE) have been considered target enzymes of depression and neurodegenerative diseases, including Alzheimer’s disease (AD).
Ashraf K. El-Damasy +6 more
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Synthesis of new metoclopramide derivatives and in vitro evaluation of their human cholinesterases protection against Chlorpyrifos [PDF]
المجلة العراقية للصيدلة, 2011 Objective: The purpose of this study was to synthesize three new derivatives of metoclopramide by diazotization and replacement reactions and then to quantify in vitro their protection effects on blood cholinesterases using chlorpyrifos as a potent ...
Islam Tarik Qasim +2 more
doaj +1 more source
Public Health and Toxicology, 2023 Determination of erythrocyte cholinesterase (AChE) and plasma cholinesterase (BChE) activities in human blood has been suggested for the diagnosis of organophosphate pesticide (OP) exposure and intoxication.
Ashwin B. Patel
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Advanced Science, EarlyView.The genome of Megachile rotundata, an extensively managed solitary pollination bee species, has been sequenced, covering 280.68 Mb and predicting 10 701 genes. The study reveals significant expansions of the Toll gene family and their abundant expression in diapause prepupae, highlighting enhanced immune responses during diapause. This genome serves as
Rangjun Shi +8 more
wiley +1 more source
Hitit Medical Journal, 2023 Objective: Organophosphates are the insecticides commonly used worldwide. Inadequate treatment in organophosphates poisoning increases morbidity, and mortality.
Muhammet Güven +8 more
doaj +1 more source
Cholinergic Degeneration and Cognitive Function in Early GBA1‐Related Parkinson's Disease
Annals of Neurology, EarlyView.Objective The phenotype of patients with Parkinson's disease carrying GBA1 variants (GBA‐PD) suggest similarities to symptomatology associated with early cholinergic system degeneration. Therefore, this study aims to investigate the clinical features and the cholinergic innervation pattern in patients with early GBA‐PD versus those without the GBA1 ...
Sofie Slingerland +6 more
wiley +1 more source
The Anatomical Record, EarlyView.Abstract Autonomic nerves are crucial in cardiac function and pathology. However, data on the distribution of cholinergic and noradrenergic nerves in normal and pathologic human hearts is lacking. Nonfailing donor hearts were pressure‐perfusion fixed, imaged, and dissected. Left ventricular cardiomyopathy samples were also obtained.
Peter Hanna +15 more
wiley +1 more source