Results 31 to 40 of about 90,058 (326)

(S)-N-Benzyl-1-phenyl-3,4-dihydroisoqunoline-2(1H)-carboxamide Derivatives, Multi-Target Inhibitors of Monoamine Oxidase and Cholinesterase: Design, Synthesis, and Biological Activity

Molecules, 2023
A series of (S)-1-phenyl-3,4-dihydroisoquinoline-2(1H)-carboxamide derivatives was synthesized and evaluated for inhibitory activity against monoamine oxidase (MAO)-A and-B, acetylcholine esterase (AChE), and butyrylcholine esterase (BChE).
Qing-Hao Jin, Li-Ping Zhang, Shan-Shan Zhang, Dai-Na Zhuang, Chu-Yu Zhang, Zhou-Jun Zheng, Li-Ping Guan   +6 more
doaj   +1 more source

The effects of donepezil in Alzheimer's disease - Results from a multinational trial [PDF]

, 1999
Donepezil has been shown to be well tolerated and to improve cognition and global function in patients with mild to moderately severe Alzheimer's disease (AD).
Burns, A., Friedhoff, L. T., Gauthier, S., Hecker, J., Möller, Hans-Jürgen, Petit, H., Rogers, S. L., Rossor, M.   +7 more
core   +1 more source

Changes of Cholinesterase Activity in the Erythrocytes, Plasma, Diaphragm, Liver and Various Parts of the Brain in the Rabbit Following Transfusion of Erythrocytes with Soman Inhibited Acetylcholinesterase

Acta Medica, 1997
1. The changes of cholinesterase activity in rabbit blood, peripheral tissues and the central nervous system following transfusion of erythrocytes with soman inhibited acetylcholinesterase were demonstrated. 2. After incubation with soman for 0.5 or 24 h,
Jiří Kassa, Jiří Bajgar, Josef Fusek
doaj   +1 more source

UPLC-MS/MS Profiling, Antioxidant, α-Glucosidase Inhibitory, Cholinesterase Inhibitory, and Cardiovascular Protection Potentials of Jialing 20 (Morus multicaulis Perr.) Mulberry Branch Extract

Foods, 2021
As a by-product in the sericulture industry, mulberry branches are not currently utilized effectively. Jialing 20 is an artificial triploids mulberry that widely cultivated in southwest China.
Wei Xiang, Zhining Xia, Li Xu
doaj   +1 more source

The impact of the use of personal-protective-equipment on the minimization of effects of exposure to pesticides among farm-workers in India

Frontiers in Public Health, 2023
IntroductionAlthough excessive use of pesticides and unsafe agricultural practices may contribute to numerous intoxications, the role of PPE (personal-protective-equipment) in the minimization of toxicological effects due to pesticide exposure has not ...
Summaiya Lari, Summaiya Lari, Praveen Yamagani, Arun Pandiyan, Janardhan Vanka, Mohan Naidu, Balakrishnan Senthil Kumar, Babban Jee, Padmaja R. Jonnalagadda   +8 more
doaj   +1 more source

Resposta à Carta ao Editor Relativa ao Trabalho “Prescrição Inapropriada em Idosos numa Enfermaria de Medicina Interna” Mariana Alves, Marco Ribeiro Narciso, Teresa Fonseca, João Gorjão Clara” [Acta Med Port.2019;32:249-249] [PDF]

, 2019
info:eu-repo/semantics ...
Urzal, JI
core   +1 more source

Vergleich dreier Ringversuche zur radioimmunologischen Thyrotropin-Bestimmung nach dem "Münchner Modell" [PDF]

, 1983
Peer ...
Habermann, J., König, A., Marschner, I., Scriba, Peter Christian, van Thiel, D., Wood, W. G.   +5 more
core   +2 more sources

IGFBP-5 as a biomarker of de-differentiation in hepatocytes [PDF]

, 2011
Describes IGFBP-5 as a biomarker of de-differentiation in hepatocytes presented at the 47th Congress of the European-Societies-of ...
Flint, David, Grant, Mary, Henderson, Catherine, Large, Emma   +3 more
core   +1 more source

Design, synthesis and evaluation of quinolinone derivatives containing dithiocarbamate moiety as multifunctional AChE inhibitors for the treatment of Alzheimer’s disease

Journal of Enzyme Inhibition and Medicinal Chemistry, 2020
A series of novel quinolinone derivatives bearing dithiocarbamate moiety were designed and synthesised as multifunctional AChE inhibitors for the treatment of AD. Most of these compounds exhibited strong and clearly selective inhibition to eeAChE.
Jie Fu, Fengqi Bao, Min Gu, Jing Liu, Zhipeng Zhang, Jiaoli Ding, Sai-Sai Xie, Jinsong Ding   +7 more
doaj   +1 more source

Cholinesterases and Engineered Mutants for the Detection of Organophosphorus Pesticide Residues

Sensors, 2018
Nowadays, pesticide residues constitute an increasing public health concern. Cholinesterases, acetylcholinesterase, and butyrylcholinesterase, are reported to be involved in detoxification processes owing to their capability of scavenging ...
Yu-Ling Xu, Feng-Ye Li, Ferdinand Ndikuryayo, Wen-Chao Yang, Hong-Mei Wang   +4 more
doaj   +1 more source