Results 61 to 70 of about 46,746 (260)

Preventive Role of Indian Black Pepper in Animal Models of Alzheimer’s Disease [PDF]

Journal of Clinical and Diagnostic Research, 2015
Introduction: Dementia is the clinical symptom of alzheimer’s disease. Brain cholinesterase levels and behavioural changes are the markers for Alzheimer’s disease and aluminium chloride is one causative agent for polymerization of tau protein and ...
Lokraj Subedee, RN Suresh, Jayanthi MK, Kalabharathi HL, Satish AM, Pushpa VH   +5 more
doaj   +1 more source

Lewy Body Dementia Research in Latin America: A Scoping Review

Movement Disorders Clinical Practice, EarlyView.
Abstract Background Dementia research in Latin America (LA) has primarily focused on Alzheimer's Disease and Frontotemporal Dementia, while Lewy body dementia (LBD) has been largely forgotten. Objective We aimed to review the available evidence on LBD in LA, offering a comprehensive perspective for understanding the lack of reports and the unique ...
Carlos Cano‐Gutiérrez, Salomón Salazar‐Londoño, Felipe Botero‐Rodriguez, Salomón Páez‐García, Salomón Giraldo, José Manuel Santacruz‐Escudero, Dag Aarsland, Miguel Germán Borda, on behalf of COL‐DLB, Felipe Botero‐Rodriguez, Miguel Germán Borda, Omar Buritica, Catalina Cerquera‐Cleves, Maria Camila Gonzalez, Elkin Garcia‐Cifuentes, Alberto Jaramillo‐Jimenez, David Aguillon, Yamile Bocanegra, Beatriz Elena Munoz‐Ospina, Carlos Alberto Cano‐Gutierrez, Carlos Tobón, Hernando Santamaría‐García, José Manuel Santacruz‐Escudero, Dag Aarsland, Jorge Orozco, Salomon Salazar‐Londoño, Luis Carlos Venegas‐Sanabria, Salomón Páez‐García, Francisco Lopera, Juan Camilo Castro, Patrick Verhelst Forero, Alexandra Ferreiròs   +31 more
wiley   +1 more source

HETEROZYGOTES FOR ATYPICAL CHOLINESTERASE

British Journal of Anaesthesia, 1982
Three hundred and thirty-two patients undergoing electroconvulsive therapy received thiopentone and suxamethonium. In 31 the duration of the apnoea was greater than an assumed upper limit of normal of 240 s. Eight of these patients proved, on biochemical grounds, to be heterozygotes for the atypical gene. The reason why the heterozygous state is rarely
H. Owen, A.R. Hunter
openaire   +3 more sources

Speech Differences between Multiple System Atrophy and Parkinson's Disease

Movement Disorders Clinical Practice, EarlyView.
Abstract Background Delineation of Parkinson's disease (PD) from multiple system atrophy (MSA) can be challenging in early disease stages. Speech characteristics have been studied as digital biomarkers in PD and ataxias. Currently, data on speech in MSA is limited.
Tom Hähnel, Anna Nemitz, Katja Schön, Luise Berger, Annemarie Vogel, Doreen Gruber, Nils Schnalke, Stefan Bräuer, Björn H. Falkenburger, Florin Gandor   +9 more
wiley   +1 more source

Cholinergic System Changes in Dopa‐Unresponsive Freezing of Gait in Parkinson's Disease

Movement Disorders, EarlyView.
Abstract Background Freezing of gait (FoG) is a debilitating mobility disturbance that becomes increasingly resistant to dopaminergic pharmacotherapies with advancing Parkinson's disease (PD). The pathophysiology underlying the response of FoG to dopaminergic treatment is poorly understood.
Kelvin L. Chou, Prabesh Kanel, Miriam van Emde Boas, Stiven Roytman, Giulia Carli, Roger L. Albin, Nicolaas I. Bohnen   +6 more
wiley   +1 more source

Cortical Effects of Dopamine Replacement Account for Clinical Response Variability in Parkinson's Disease

Movement Disorders, EarlyView.
Abstract Background Individual variability in clinical response to dopamine replacement therapy (DRT) is a key barrier to efficacious treatment for patients with Parkinson's disease (PD). A better understanding of the neurobiological sources of such interindividual differences is necessary to personalize DRT prescribing, inform future clinical ...
Alex I. Wiesman, Mikkel C. Vinding, Panagiota Tsitsi, Per Svenningsson, Josefine Waldthaler, Daniel Lundqvist   +5 more
wiley   +1 more source

Acute exposure to fenthion in juveniles of white cachama (Piaractus brachypomus): toxic effects, changes in cholinesterase activity and potential use in environmental monitoring

Revista Ciencias de la Salud, 2012
Fenthion is an organophosphate insecticide used worldwide that may pollute waters after itsapplication causing potential problems in public health and poisoning in domestic and wildlifeanimals.
Borbón Javier F., González-Mantilla Jaime Fernando   +1 more
doaj  

Bilateral Focused Ultrasound Thalamotomy for Essential Tremor: Clinical Outcomes Compared to Bilateral Deep Brain Stimulation and Probabilistic Lesion Mapping

Movement Disorders, EarlyView.
Abstract Background The efficacy and adverse events (AEs) of bilateral magnetic resonance‐guided focused ultrasound (MRgFUS) thalamotomies for essential tremor (ET) have not been compared to those of deep brain stimulation (DBS). Furthermore, it is uncertain whether second‐side thalamotomies can be positioned differently from the first without ...
Can Sarica, Kazuaki Yamamoto, Christian Iorio‐Morin, Jurgen Germann, Andrew Z. Yang, Brendan Santyr, Michael Colditz, Artur Vetkas, Anton Fomenko, Benjamin Davidson, Franziska Schmidt, Talyta Grippe, Nardin Samuel, Ajmal Zemmar, Oliver Flouty, Cletus Cheyuo, Ghazaleh Darmani, Robert Chen, Alexandre Boutet, Clemens Neudorfer, Mojgan Hodaie, Suneil K. Kalia, Renato P. Munhoz, Alfonso Fasano, Andres M. Lozano   +24 more
wiley   +1 more source

Cholinesterase in Junction Nevus

Journal of Investigative Dermatology, 1963
!The neural origin of all intradermal nevus cells has been proposed on the basis of their cholinesterase activity and lack of tyrosinase in contrast to the junction nevus cell (1, 2). However, tyrosinase studies of intradermal nevi after ultraviolet irradiation reveal not only an intensified dopa reaction but also a positive tyrosinase reaction in ...
Frederick F. Schaub, Yutaka Mishima
openaire   +3 more sources

Neuronally‐Derived Extracellular Vesicles Transforming Growth Factor Beta‐1 Levels in Progressive Supranuclear Palsy

Movement Disorders, EarlyView.
Abstract Background Differentiating progressive supranuclear palsy (PSP) from other parkinsonian disorders may be challenging. Objectives To investigate the role of transforming growth factor beta‐1 (TGFβ1) in PSP. Methods A total of 33 PSP, 39 Parkinson's disease (PD), 8 multiple system atrophy (MSA) patients, and 50 healthy controls (HC) were ...
Selena Mimmi, Elvira Immacolata Parrotta, Anna Maria Tolomeo, Domenico Maisano, Valentina Crapella, Elisabetta Pingitore, Khushboo Fatima, Anna Maria Zimbo, Mariagrazia Talarico, Costanza Maria Cristiani, Luana Scaramuzzino, Desirèe Valente, Clara Zannino, Gianni Cuda, Aldo Quattrone, Enrico Iaccino, Andrea Quattrone   +16 more
wiley   +1 more source