Results 111 to 120 of about 2,823,581 (316)

Association between CMR‐derived hepatic T1‐time, tricuspid regurgitation and survival

open access: yesEuropean Journal of Clinical Investigation, EarlyView.
We investigated the association between tricuspid regurgitation (TR) severity and hepatic T1‐time in 1029 patients undergoing cardiac MRI and echocardiography. Hepatic T1‐time increased progressively with TR severity and remained independently associated after adjusting for NT‐proBNP and right ventricular function. Both TR and hepatic T1‐time predicted
Katharina Mascherbauer   +19 more
wiley   +1 more source

Consumption trends for specific drugs used to treat dementia in the region of Madrid (Spain) from 2002 to 2012

open access: yesNeurología (English Edition), 2015
Introduction: Analysing drug consumption in large population groups lets us observe consumption trends and compare them between different settings. Objective: To analyse the time trends for consumption and costs of specific drugs used to treat dementia ...
M.C. de Hoyos-Alonso   +4 more
doaj  

The human photosensitive epilepsy model for clinical proof‐of‐principle trials of novel antiseizure medications: 2. Analysis of drug trials and predictive value of the model

open access: yesEpilepsia, EarlyView.
Abstract Clinical development of novel antiseizure medications (ASMs) would benefit from an early proof of principle (POP) model. The photosensitivity model, which uses the photoparoxysmal electroencephalographic response (PPR) as a surrogate of seizures, is currently the only human model that allows POP trials of investigational compounds after a ...
Wolfgang Löscher   +1 more
wiley   +1 more source

Assessing the Content of Goals of Care Documentation for Hospitalized Patients With Alzheimer's Disease and Related Dementias

open access: yesJournal of the American Geriatrics Society, EarlyView.
Documented Patient Values and Preferences and Attendance at Goals of Care Conversations. AD/ADRD—Alzheimer's disease and related dementias. ABSTRACT Background Goals of care (GOC) conversations are an evidence‐based practice that help clarify and align patient values and preferences for medical care with treatment options.
Gina Piscitello   +5 more
wiley   +1 more source

Two cases of Alzheimer's disease showing deterioration of behavioral and psychological symptoms of dementia induced by switching from rivastigmine to donepezil

open access: yesNeuropsychiatric Disease and Treatment, 2012
Takemi Kimura, Junichi TakamatsuDivision of Clinical Research, National Hospital Organization Kikuchi Hospital, Koshi, Kumamoto, JapanAbstract: Rivastigmine, galantamine, and memantine, in addition to donepezil, which has been on the market over 10 years,
Kimura T, Takamatsu J
doaj  

Implementation of Lecanemab for Alzheimer's Disease Within the Veterans Health Administration: Facilitators and Barriers

open access: yesJournal of the American Geriatrics Society, EarlyView.
ABSTRACT Background Several amyloid targeting therapies have been approved for Alzheimer's disease (AD), including lecanemab (Leqembi). However, real‐world implementation of these drugs has uncovered significant challenges. Methods We conducted a national cross‐sectional survey of healthcare professionals from multiple disciplines participating in the ...
Alison J. O'Donnell   +5 more
wiley   +1 more source

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