Results 31 to 40 of about 2,781,261 (274)
Medium dependence of asphaltene agglomeration inhibitor efficiency [PDF]
Energy & Fuels vol.22, 2008, pp 1917 - 1922;, 2007 Applying chemical additives (molecule inhibitors or dispersants) is one of the common ways to control asphaltene agglomeration and precipitation. However, it is not clear why at some conditions the synthetic flocculation inhibitors as well as resins not only do not inhibit the asphaltene agglomeration,, they may also promote it, and why the increasing ...
arxiv +1 more source
Understanding Alzheimer disease
South African Family Practice, 2019 Alzheimer disease (AD) is a neurodegenerative disorder with an uncertain pathogenesis. It is characterised by symptoms of memory impairment, executive dysfunction and visuospatial impairment.
M. Vally, F. Kathrada
doaj +1 more source
Metabolite profile and in vitro cholinesterase inhibitory activity of extract and fractions of Aaptos suberitoides [PDF]
Journal of Pharmacy & Pharmacognosy Research, 2023 Context: Marine sources such as sponges have shown a significant impact on the drug development from nature. Metabolites isolated from sponges show diversity in terms of structural features and pharmacological properties.
Hanifa R. Putri +7 more
doaj +1 more source
An Overview of 1,2,3-triazole-Containing Hybrids and Their Potential Anticholinesterase Activities
Pharmaceuticals, 2023 Acetylcholine (ACh) neurotransmitter of the cholinergic system in the brain is involved in learning, memory, stress responses, and cognitive functioning.
Shah Alam Khan +4 more
doaj +1 more source
Cochrane Database of Systematic Reviews, 2019 This is a protocol for a Cochrane Review (Intervention). The objectives are as follows: To assess the benefits and harms of each cholinesterase inhibitor in the treatment of adults with VCI.
C. Battle +4 more
semanticscholar +1 more source
Deprescribing cholinesterase inhibitors and memantine in dementia: guideline summary
Medical Journal of Australia, 2019 Cholinesterase inhibitors (ChEIs) and memantine are medications used to treat the symptoms of specific types of dementia. Their benefits and harms can change over time, particularly during long term use.
E. Reeve +10 more
semanticscholar +1 more source
Position Statement on Anti-Dementia Medication for Alzheimer’s Disease by Swiss Stakeholders
Clinical and Translational Neuroscience, 2021 The present document represents the position of Swiss health-care associations, clinical and research centers, research-supporting foundations, and the association Alzheimer Switzerland regarding the care of persons with dementia and Alzheimer’s disease.
Giovanni B Frisoni +17 more
doaj +1 more source
Cholinesterase inhibitors from botanicals
Pharmacognosy Reviews, 2013 Alzheimer's disease (AD) is a progressive neurodegenerative disease, wherein a progressive loss of cholinergic synapses occurs in hippocampus and neocortex. Decreased concentration of the neurotransmitter, acetylcholine (ACh), appears to be critical element in the development of dementia, and the most appropriate therapeutic approach to treat AD and ...
Raza Murad Ghalib +3 more
openaire +3 more sources
Novel structural features of CDK inhibition revealed by an ab initio computational method combined with dynamic simulations [PDF]
Journal of Medicinal Chemistry 49, 5141-5153 (2006), 2008 The rational development of specific inhibitors for the ~500 protein kinases encoded in the human genome is impeded by a poor understanding of the structural basis for the activity and selectivity of small molecules that compete for ATP binding. Combining classical dynamic simulations with a novel ab initio computational approach linear-scalable to ...
arxiv +1 more source
Alzheimer's Research & Therapy, 2018 Cholinesterase inhibitors and memantine have been approved for management of Alzheimer’s disease (AD), but there has been no consensus about the choice of various types and doses of drugs at different stages.
Kaixin Dou +8 more
semanticscholar +1 more source