Results 31 to 40 of about 2,823,581 (316)
Metabolite profile and in vitro cholinesterase inhibitory activity of extract and fractions of Aaptos suberitoides [PDF]
Journal of Pharmacy & Pharmacognosy Research, 2023 Context: Marine sources such as sponges have shown a significant impact on the drug development from nature. Metabolites isolated from sponges show diversity in terms of structural features and pharmacological properties.
Hanifa R. Putri +7 more
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An Overview of 1,2,3-triazole-Containing Hybrids and Their Potential Anticholinesterase Activities
Pharmaceuticals, 2023 Acetylcholine (ACh) neurotransmitter of the cholinergic system in the brain is involved in learning, memory, stress responses, and cognitive functioning.
Shah Alam Khan +4 more
doaj +1 more source
Cochrane Database of Systematic Reviews, 2019 This is a protocol for a Cochrane Review (Intervention). The objectives are as follows: To assess the benefits and harms of each cholinesterase inhibitor in the treatment of adults with VCI.
C. Battle +4 more
semanticscholar +1 more source
Inhibitory effect of benzimidazole derivatives on cholinesterases of animals in the presence of different substrates [PDF]
The Ukrainian Biochemical Journal, 2014 Specifically synthesized group of benzimidazole derivatives possessing varying degrees of delocalization of the positive charge in the cation group of the molecule has been studied in order to search for potential cholinergically active compounds and to
N. E. Basova +5 more
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Position Statement on Anti-Dementia Medication for Alzheimer’s Disease by Swiss Stakeholders
Clinical and Translational Neuroscience, 2021 The present document represents the position of Swiss health-care associations, clinical and research centers, research-supporting foundations, and the association Alzheimer Switzerland regarding the care of persons with dementia and Alzheimer’s disease.
Giovanni B Frisoni +17 more
doaj +1 more source
Deprescribing cholinesterase inhibitors and memantine in dementia: guideline summary
Medical Journal of Australia, 2019 Cholinesterase inhibitors (ChEIs) and memantine are medications used to treat the symptoms of specific types of dementia. Their benefits and harms can change over time, particularly during long term use.
E. Reeve +10 more
semanticscholar +1 more source
Cholinesterase inhibitors from botanicals
Pharmacognosy Reviews, 2013 Alzheimer's disease (AD) is a progressive neurodegenerative disease, wherein a progressive loss of cholinergic synapses occurs in hippocampus and neocortex. Decreased concentration of the neurotransmitter, acetylcholine (ACh), appears to be critical element in the development of dementia, and the most appropriate therapeutic approach to treat AD and ...
Raza Murad Ghalib +3 more
openaire +3 more sources
Alzheimer's Research & Therapy, 2018 Cholinesterase inhibitors and memantine have been approved for management of Alzheimer’s disease (AD), but there has been no consensus about the choice of various types and doses of drugs at different stages.
Kaixin Dou +8 more
semanticscholar +1 more source
Arquivos de Neuro-PsiquiatriaIn light of the high cost of dementia treatment, there is legislation authorizing free distribution of cholinesterase inhibitors to those suffering from Alzheimer’s disease in Brazil.
Flávia Silva de Moraes +3 more
doaj +1 more source
Computer-aided approach for the identification of lead molecules as the inhibitors of cholinesterase’s and monoamine oxidases: Novel target for the treatment of Alzheimer disease [PDF]
Journal of the Serbian Chemical SocietyMolecular docking is a promising and reliable technology for the purpose of discovering lead compounds via virtual screening. In addition to allowing for the testing of a large number of compounds, it also allows for the determination of how the selected
Ejaz Syeda Abida +4 more
doaj +1 more source