Results 61 to 70 of about 2,781,261 (274)

Mucin-inspired, high molecular weight virus binding inhibitors show biphasic binding behavior to influenza A viruses [PDF]

open access: yesarXiv, 2020
Multivalent virus binding inhibitors are a promising new class of antivirals, preventing virus infection of cells by inhibiting the first step in the viral infection cycle - binding of viruses to the cell surface. The design of multivalent virus binding inhibitors is complex as many properties, such as inhibitor size and functionalization with virus ...
arxiv  

Association of Concomitant Use of Cholinesterase Inhibitors or Memantine With Cognitive Decline in Alzheimer Clinical Trials

open access: yesJAMA Network Open, 2018
Key Points Question Are cholinesterase inhibitors or memantine associated with cognitive outcomes in clinical trials for Alzheimer disease? Findings In this meta-analysis, participants receiving cholinesterase inhibitors or memantine had 1.4 points per ...
R. Kennedy   +3 more
semanticscholar   +1 more source

Connecting the dots: A narrative review of the relationship between heart failure and cognitive impairment

open access: yesESC Heart Failure, Volume 12, Issue 2, Page 1119-1131, April 2025.
Abstract Large clinical data underscore that heart failure is independently associated to an increased risk of negative cognitive outcome and dementia. Emerging evidence suggests that cerebral hypoperfusion, stemming from reduced cardiac output and vascular pathology, may contribute to the largely overlapping vascular dementia and Alzheimer's disease ...
Mauro Massussi   +6 more
wiley   +1 more source

Anti-cholinergic drug burden in patients with dementia increases after hospital admission: a multicentre cross-sectional study

open access: yesBMC Geriatrics, 2022
Background Anticholinergic medications are drugs that block cholinergic transmission, either as their primary therapeutic action or as a secondary effect.
Annabelle Hook   +29 more
doaj   +1 more source

Hydrazones of 4-(Trifluoromethyl)benzohydrazide as New Inhibitors of Acetyl- and Butyrylcholinesterase

open access: yesMolecules, 2021
Based on the broad spectrum of biological activity of hydrazide–hydrazones, trifluoromethyl compounds, and clinical usage of cholinesterase inhibitors, we investigated hydrazones obtained from 4-(trifluoromethyl)benzohydrazide and various benzaldehydes ...
Martin Krátký   +4 more
doaj   +1 more source

METAB‐HTX: prospective, longitudinal cohort study evaluating cardiac and systemic metabolism after heart transplantation

open access: yesESC Heart Failure, EarlyView.
The METAB‐HTX trial is a prospective cohort study, evaluating cardiac and systemic metabolism among heart transplant recipients. Myocardial function, energetic and metabolism, allograft vasculopathy, allograft rejection, glucometabolism, lipometabolism, liver‐ and kidney function, leucocyte signatures and thromboinflammation will be evaluated ...
Amin Polzin   +21 more
wiley   +1 more source

CHOLINESTERASE INHIBITORS IN THE TREATMENT OF DEMENTIA ALZHEIMER’S

open access: yese-Jurnal Medika Udayana, 2013
Dementia is the loss of intellectual abilities which include decreased ability to think, remember,understand, calculate, concentrate, and find the right words. The causes of dementia areAlzheimer’s, vascular dementia, alcohol.
Prameidya Primaniar S
doaj  

Difficulties in Diagnosing a Case of Myasthenia Crisis

open access: yesJournal of Clinical and Biomedical Sciences, 2020
A 26 year old, female presented to EMD in severe respiratory distress. Patient had history of breathlessness since past one month with h/o intrauterine death 1month back .On further investigation it was found that anti acetylcholine receptor ...
Atishaya G V   +3 more
doaj   +1 more source

New Carrier Made from Glass Nanofibres for the Colorimetric Biosensor of Cholinesterase Inhibitors

open access: yesBiosensors, 2018
Cholinesterase inhibitors are widely used as pesticides in agriculture, but also form a group of organophosphates known as nerve chemical warfare agents.
L. Matějovský, V. Pitschmann
semanticscholar   +1 more source

Actinidia spp. (Kiwifruit): A Comprehensive Review of Its Nutraceutical Potential in Disease Mitigation and Health Enhancement

open access: yesFood Frontiers, EarlyView.
Nutraceutical Potential in Disease Mitigation and Health Enhancement of Actinidia spp. (Kiwifruit) ABSTRACT This review offers an in‐depth exploration of the Actinidia species (kiwifruit) nutritional composition, the pivotal role of its primary bioactive compounds, and their potential applications across the aforementioned health concerns. Furthermore,
Allah Rakha   +7 more
wiley   +1 more source

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