Results 61 to 70 of about 42,628 (216)

CHOLINESTERASE INHIBITORS IN THE TREATMENT OF DEMENTIA ALZHEIMER’S

e-Jurnal Medika Udayana, 2013
Dementia is the loss of intellectual abilities which include decreased ability to think, remember,understand, calculate, concentrate, and find the right words. The causes of dementia areAlzheimer’s, vascular dementia, alcohol.
Prameidya Primaniar S
doaj  

Hydrazones of 4-(Trifluoromethyl)benzohydrazide as New Inhibitors of Acetyl- and Butyrylcholinesterase

Molecules, 2021
Based on the broad spectrum of biological activity of hydrazide–hydrazones, trifluoromethyl compounds, and clinical usage of cholinesterase inhibitors, we investigated hydrazones obtained from 4-(trifluoromethyl)benzohydrazide and various benzaldehydes ...
Martin Krátký, Katarína Svrčková, Quynh Anh Vu, Šárka Štěpánková, Jarmila Vinšová   +4 more
doaj   +1 more source

Cholinesterase Enzymes Inhibitors from the Leaves of Rauvolfia Reflexa and Their Molecular Docking Study [PDF]

, 2013
molecule
A. Hadi, A. Hamid, Alireza Basiri, Mehran Fadaeinasab, Vikneswaran Murugaiyah, Yalda Kia   +5 more
core   +2 more sources

Ethnic and Gender Disparities in Access to Deep Brain Stimulation Surgery for Parkinson's Disease

Movement Disorders Clinical Practice, EarlyView.
Abstract Background Deep brain stimulation (DBS) is an established treatment for Parkinson's disease (PD) in appropriately selected patients. DBS may be underused in certain patient populations, especially women and racialized groups. Barriers and biases to receiving DBS that could account for underuse among these groups are not well studied in Canada.
Fang Ba, Sabrina Poonja, Pouria Torabi, Kevin Yen, Bashir Daud Shah, Eric Noyes, Gail Dimapilis, Shaina Corrick, Tejas Sankar, Alex Rajput, Oury Monchi, Aleksander M. Vitali, Bukola Salami, Aakash Shetty, Janis M. Miyasaki   +14 more
wiley   +1 more source

Synthesis, X-Rays Analysis, Docking Study and Cholinesterase Inhibition Activity of 2,3-dihydroquinazolin-4(1H)-one Derivatives [PDF]

Iranian Journal of Chemistry & Chemical Engineering, 2019
In search of potent cholinesterase inhibitors, we have carried out the synthesis and biologically evaluation of various benzaldehyde based 2,3-dihydroquinazolin-4(1H)-one derivatives.
Muhammad Sarfraz, Umer Rashid, Nargis Sultana, Muhammad Ilyas Tariq   +3 more
doaj  

Comparative Analysis of the Incidence, Prevalence, and Survival of 8 Types of Parkinsonism in a Population‐Based Study with 367 Million Person Years of Observation over 21 Years

Movement Disorders Clinical Practice, EarlyView.
Abstract Background Findings are contradictory regarding changes in the incidence and prevalence of Parkinson's disease (PD) over time; data for other parkinsonian disorders are rare. Objectives To analyze temporal trends in the incidence and prevalence of eight parkinsonisms (PD, MSA, PSP, CBS, DLB, vascular parkinsonism, drug‐induced parkinsonism ...
Sacha E. Gandhi, Katherine A. Grosset, Prasanth A. Iruthayaraj, Romel Gravesande, Lance Lee, Cathal Doyle, Yoav Ben‐Shlomo, Donald G. Grosset   +7 more
wiley   +1 more source

Clinical Signs of Poisoning with Pyrethroid and Cholinesterase Inhibitors

مجله دانشکده پزشکی اصفهان, 2011
Background: Due to the similarities between clinical signs of toxicity with pyrethroids and cholinesterase inhibitors, if the mistake between these two was made and the patient was treatment with atropine, severe atropine poisoning and even death could ...
Farzad Gheshlaghi, Zohreh Sedighinia
doaj  

Tolerability of ORM-12741 and effects on episodic memory in patients with Alzheimer's disease [PDF]

, 2016
Introduction ORM-12741 is a novel selective antagonist of alpha-2C adrenoceptors. This trial evaluated the safety and efficacy of ORM-12741 in patients with Alzheimer's disease (AD).
Cummings, Jeffrey, Hakulinen, Pasi, Hallikainen, Merja, Hänninen, Jutta, Murphy, Michael, Rinne, Juha, Riordan, Henry, Rouru, Juha, Scheinin, Mika, Soininen, Hilkka, Wesnes, Keith   +10 more
core   +1 more source

Ocular Motor Abnormalities in Functional Neurological Disorder: A Video‐Oculography Study

Movement Disorders Clinical Practice, EarlyView.
Abstract Background Functional neurological disorders (FND) can include various sensory, motor or cognitive symptoms. Eye movement recordings, measured through video‐oculography, could serve as biomarkers for characterizing these dysfunctions in FND.
Aude Sangare, Astrid de Liège, Bertrand Gaymard, Sophie Rivaud‐Péchoux, Cécilia Bonnet, Evžen Růžička, Jaromír May, Tereza Serranová, Francine Mesrati, Emmanuel Roze, Marie Vidailhet, Céline Louapre, Lionel Naccache, Béatrice Garcin   +13 more
wiley   +1 more source

Impact of amyloid PET in the clinical care of veterans in a tertiary memory disorders clinic

Alzheimer’s & Dementia: Translational Research & Clinical Interventions, 2022
Introduction We aimed to characterize the clinical impact of amyloid PET (APET) in a veteran population with cognitive decline by comparing differences in management between those who did and did not have an APET.
Ana Laura Vives‐Rodriguez, Kylie A. Schiloski, Anna Marin, Ryan Wang, Gabor P. Hajos, Rachel Powsner, Renée DeCaro, Andrew E. Budson, Katherine W. Turk   +8 more
doaj   +1 more source