Results 141 to 150 of about 853 (162)

The history of cholinesterase reactivation: hydroxylamine and pyridinium aldoximes.

Die Pharmazie, 2012
Hydroxylamine (NH2OH) the substance which will turn out to be of importance to those interested in the treatment of organophosporus cholinesterase inhibitor exposure, was synthesized by Wilhem Clemens Lossen in 1865 while working in Halle as an assistant in the laboratory of Wilhelm Heinrich Heintz.
openaire   +2 more sources

Oxime reactivation of cholinesterases inhibited by enantiomeric organophosphonates

2000
Mouse acetylcholinesterase (AChE) and its mutants, and mouse butyrylcholinesterase (BChE), were inhibited with enantiomeric SP- and RP- cycloheptyl- (CHMP), isopropyl- (iPrMP), and dimethylbutyl- (DMBMP) methylphosphonyl thiocholines and resulting conjugates subjected to reactivation with oximes 2-PAM or HI-6.
Kovarik, Zrinka, Wong, Lilly, Radić, Zoran, Berman, Harvey A., Taylor, Palmer   +4 more
openaire   +3 more sources

Reactivators of cholinesterase

Pharmaceutical Chemistry Journal, 1968
I. N. Somin, S. G. Kuznetsov
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Novel cholinesterase reactivators

2020
Kamil Musilek, David Malinak, Eugenie Nepovimova, Rudolf Andrys, Adam Skarka, Kamil Kuca   +5 more
openaire   +1 more source

The ganglionic blocking properties of the cholinesterase reactivator, HS-6

Canadian Journal of Physiology and Pharmacology, 1978
Following intravenous administration of the cholinesterase reactivator HS-6 (30 mg/kg), blood pressure fell (up to 50 mmHg) and maximal blood levels of HS-6 reached 242 μg/ml. HS-6 attenuated the pressor response resulting from carotid occlusion and the depressor effect of vagal stimulation.
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[Central action of a new cholinesterase reactivator, diethyxime].

Farmakologiia i toksikologiia, 1978
In anesthetized cats, whose peripheral muscarinic-cholinorecptors are blocked by m-cholinolytics (benzilyl choline) failing to penetrate into the brain, the cholinesterases reactivator diethyxime debars the centrally caused fall of the arterial pressure produced by armine, an inhibitor of cholinesterases readily gaining access into the brain ...
B K, Beznosko, I B, Voronov, E E, Feĭgman, V E, Krivenchuk   +3 more
openaire   +1 more source

REACTIVATION OF NEOSTIGMINE INHIBITED HUMAN PLASMA CHOLINESTERASE

The Journal of Pharmacology and Experimental Therapeutics, 1960
F F, FOLDES, E G, ERDOS, E K, ZSIGMOND, J A, ZWARTZ   +3 more
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Novel Cholinesterase Reactivators

2015
Kamil Musilek, Jan Korabecny, Daniel Jun, Jiri Kassa, Kamil Kuca   +4 more
openaire   +1 more source

Action of Reactivators of Cholinesterase Applied by Inhalation

Chemotherapy, 1962
B, BOSKOVIC, P, STERN
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Changes in butyryl cholinesterase activity in reactive glia

Neurology, 1966
U, Roessmann, R L, Friede
openaire   +2 more sources