Results 91 to 100 of about 12,590 (219)

On the Reducible Character of Haldane-Radić Enzyme Kinetics to Conventional and Logistic Michaelis-Menten Models

Molecules, 2011
The conceptual and practical issues regarding the reduction of the Haldane-Radić enzymic mechanism, specific for cholinesterase kinetics, to the consecrated or logistically modified Michaelis-Menten kinetics, specific for some mutant enzymes, are here ...
Mihai V. Putz
doaj   +1 more source

Usporedba protokola za mjerenje aktivnosti kolinesteraza u ljudskoj krvi Ellmanovom metodom [PDF]

, 2000
This paper presents a protocol for routine assays of human blood cholinesterase activities which separates erythrocytes from plasma by centrifugation and measures acetylcholinesterase activity in unwashed erythrocytes and butyrylcholinesterase activity ...
Elsa Reiner, Goran Šinko, Mira Škrinjarić-Špoljar, Vera Simeon-Rudolf   +3 more
core  

Synthesis of p‐Coumarates With Potential Anti‐Alzheimer's Action: Enzyme Inhibition and In Silico Studies

Chemistry &Biodiversity, Volume 23, Issue 4, April 2026.
ABSTRACT Alzheimer's disease (AD) is a fatal neurodegenerative disorder that affects cognition, memory, and behavior. Such a disease is considered the most common cause of dementia and affects a large portion of the elderly population worldwide. Currently, cholinesterase inhibitors are used to reduce the symptoms and rate of progression of this disease.
Susiany Pereira Lopes, Jeremias Justo Emídio, Allana Brunna Sucupira Duarte, Ilkay Erdogan Orhan, Fatma Sezer Senol Deniz, Ramin Ekhteiari Salmas, Damião Pergentino de Sousa   +6 more
wiley   +1 more source

Resorcinol-, catechol- and saligenin-based bronchodilating β2-agonists as inhibitors of human cholinesterase activity

Journal of Enzyme Inhibition and Medicinal Chemistry, 2017
We investigated the influence of bronchodilating β2-agonists on the activity of human acetylcholinesterase (AChE) and usual, atypical and fluoride-resistant butyrylcholinesterase (BChE). We determined the inhibition potency of racemate and enantiomers of
Anita Bosak, Anamarija Knežević, Ivana Gazić Smilović, Goran Šinko, Zrinka Kovarik   +4 more
doaj   +1 more source

Sparassis crispa and a Bioactive Compound Therein, Ergosterol, Were Effective in Preventing Acetylcholinesterase Inhibition In Vitro and In Vivo

Food Science &Nutrition, Volume 14, Issue 4, April 2026.
Sparassis crispa extract exhibited acetylcholinesterase inhibitory and antioxidant activities, and ergosterol was identified as a major bioactive sterol. In a TMT‐induced mouse model, both the extract and ergosterol improved spatial working memory and learning retention while reducing brain AChE activity and lipid peroxidation.
Chan Kyu Park, Gyumin Kang, Soo Jung Choi, Yoon Seo Lee, Eui‐Cheol Shin, Hyo In Kim, Jinbong Park, Nam Su Oh, Hyung Taek Cho, Tae Gyun Kim, Jeong Hoon Pan, Dong‐Hoon Shin, Young‐Jun Kim, Jae Kyeom Kim   +13 more
wiley   +1 more source

Predicting outcome using butyrylcholinesterase activity in organophosphorus pesticide self-poisoning [PDF]

, 2008
Background: The usefulness of a low butyrylcholinesterase (BuChE) activity on admission for predicting severity in acute organophosphorus (OP) insecticide poisoning has long been debated. Previous studies have been confounded by the inclusion of multiple
Buckley, N. A., Eddleston, M., Eyer, P., Sheriff, M. H. Rezvi, Worek, F.   +4 more
core   +1 more source

Synthesis, Bioactivity and Molecular Modeling Studies on Benzimidazole Derivatives and Its Isosteres as Potent AChE/BChE and GSK3β Inhibitors for Alzheimer's Disease

Chemical Biology &Drug Design, Volume 107, Issue 4, April 2026.
Compounds 1j, 1l, 2b, 2j, 3g, and 3l were found to have potent anti‐Alzheimer agents for AChE, BChE inhibitions, neuroprotective effects in the presence of H2O2 and GSK3β inhibitions. ABSTRACT A series of benzimidazoles and its analogs (benzoxazoles and benzothiazoles) bearing a benzohydrazide‐hydrazones moiety at the 2‐position were designed and ...
Gözde Sayar, Sulunay Parlar, Ayse Hande Tarikogullari, Mumin Alper Erdoğan, Guliz Armagan, Vildan Alptuzun   +5 more
wiley   +1 more source

Presence of cholinesterases in Echinococcus granulosus protoscolices

Parasite, 2000
Cholinesterases were detected in protoscolices of Echinococcus granulosus spectrophotometrically and electrophoretically. To characterize these activities as acetylcholinesterases or pseudocholinesterases, BW284C51 and the organophosphate anthelmintic ...
Giménez-Pardo C., Ros Moreno R.M., De Armas-Serra C., Rodriguez-Caabeiro F.   +3 more
doaj   +1 more source

Structure Related Inhibition of Enzyme Systems in Cholinesterases and BACE1 In Vitro by Naturally Occurring Naphthopyrone and Its Glycosides Isolated from Cassia obtusifolia

Molecules, 2017
Cassia obtusifolia Linn. have been used to improve vision, inflammatory diseases, and as hepatoprotective agents and to promote urination from ancient times.
Srijan Shrestha, Su Hui Seong, Pradeep Paudel, Hyun Ah Jung, Jae Sue Choi   +4 more
doaj   +1 more source

SchussenAktivplus: reduction of micropollutants and of potentially pathogenic bacteria for further water quality improvement of the river Schussen, a tributary of Lake Constance, Germany [PDF]

, 2013
The project focuses on the efficiency of combined technologies to reduce the release of micropollutants and bacteria into surface waters via sewage treatment plants of different size and via stormwater overflow basins of different types. As a model river
Amler, Klaus, Blaha, Ludek, Gallert, Claudia, Giebner, Sabrina, Güde, Hans, Henneberg, Anja, Hess, Stefanie, Hetzenauer, Harald, Jedele, Klaus, Jung, Ralph-Michael, Kneipp, Sven, Krais, Stefanie, Kuch, Bertram, Köhler, Heinz-R., Lange, Claudia, Löffler, Herbert, Maier, Diana, Metzger, Jörg, Müller, Michael, Oehlmann, Jörg, Osterauer, Raphaela, Peschke, Katharina, Raizner, Jürgen, Rault, Magali, Rey, Peter, Richter, Doreen, Sacher, Frank, Scheurer, Marco, Schneider-Rapp, Jutta, Seifan, Merav, Spieth, Markus, Triebskorn, Rita, Vogel, Hans-Joachim, Weyhmüller, Michael, Winter, Josef, Wurm, Karl   +35 more
core   +1 more source