Results 21 to 30 of about 27,370 (335)

Butyrylcholinesterase and Acetylcholinesterase polymorphisms in Multiple Sclerosis patients: Implication in peripheral inflammation [PDF]

, 2018
Multiple Sclerosis (MS) is an autoimmune disease, having not fully understood aetiology, and both genetic and environmental factors contribute to the pathogenesis of the disease.
Costantini, Erica, D'Angelo, Chiara, D'Aurora, Marco, Di Bari, Maria, Di Nicola, Marta, Franchi, Sara, Galizia, Sabrina, Gasperini, Claudio, Gatta, Valentina, Orlando, Viviana, Reale, Marcella, Ruggieri, Serena, Stuppia, Liborio, Tata, Ada Maria   +13 more
core   +2 more sources

Chemical characterization of sulfated polysaccharides from Gracilaria gracilis and Ulva lactuca and their radical scavenging, metal chelating, and cholinesterase inhibitory activities

International Journal of Food Properties, 2019
This study was designed to evaluate the antioxidant and cholinesterase inhibitory activities of sulfated polysaccharides from Gracilaria gracilis (PGCL) and Ulva lactuca (PULV).
Tosin A. Olasehinde, Leonard V. Mabinya, Ademola O. Olaniran, Anthony I. Okoh   +3 more
doaj   +1 more source

Effect of DBS detergent on activity of some enzymes of young carp (Cyprinus carpio L.) in brain, gills, and serum [PDF]

Acta Ichthyologica et Piscatoria, 1977
Effects of DBS (natrium dodecyl-benzene-sulphonate) on the activity of ATP-ases and cholinesterases of autumn young carp brain, gills, and serum were studied. On the second day of the brain ATP-ases activity was found to increase by ca 120%.
M.K. Jurkowski
doaj   +3 more sources

Mangifera indica ‘Namdokmai’ Prevents Neuronal Cells from Amyloid Peptide Toxicity and Inhibits BACE-1 Activities in a Drosophila Model of Alzheimer’s Amyloidosis

Pharmaceuticals, 2022
Alzheimer’s disease (AD) is a progressive neurological illness with few effective treatments. Thus, ameliorating the effects of AD using natural products has attracted global attention with promising efficacy and safety.
Piya Temviriyanukul, Suwapat Kittibunchakul, Piyapat Trisonthi, Thanit Kunkeaw, Woorawee Inthachat, Dalad Siriwan, Uthaiwan Suttisansanee   +6 more
doaj   +1 more source

In-Vitro, In-Vivo, Molecular Docking and ADMET Studies of 2-Substituted 3,7-Dihydroxy-4H-chromen-4-one for Oxidative Stress, Inflammation and Alzheimer’s Disease

Metabolites, 2022
Plants’ bioactives are well-known safe drugs for vital diseases. Flavones and Flavonoid-rich dietary supplements are known to exhibit neuroprotective potential.
Mater H. Mahnashi, Mohammed Abdulrahman Alshahrani, Mohammed H. Nahari, Syed Shams ul Hassan, Muhammad Saeed Jan, Muhammad Ayaz, Farhat Ullah, Osama M. Alshehri, Mohammad Ali Alshehri, Umer Rashid, Abdul Sadiq   +10 more
doaj   +1 more source

The Role of Cholinesterases in Post-Exercise HRV Recovery in University Volleyball Players

Applied Sciences, 2021
Some studies show interest in measuring heart rate variability (HRV) during post-exercise recovery. It is known that the parasympathetic system is relevant during this process, where one of the factors of this modulation is the interaction of ...
José Raúl Hoyos-Flores, Blanca R. Rangel-Colmenero, Zeltzin N. Alonso-Ramos, Myriam Z. García-Dávila, Rosa M. Cruz-Castruita, José Naranjo-Orellana, Germán Hernández-Cruz   +6 more
doaj   +1 more source

Neuroprotective Potential of Synthetic Mono-Carbonyl Curcumin Analogs Assessed by Molecular Docking Studies

Molecules, 2021
Cognitive decline in dementia is associated with deficiency of the cholinergic system. In this study, five mono-carbonyl curcumin analogs were synthesized, and on the basis of their promising in vitro anticholinesterase activities, they were further ...
Haya Hussain, Shujaat Ahmad, Syed Wadood Ali Shah, Mehreen Ghias, Abid Ullah, Shafiq Ur Rahman, Zul Kamal, Farman Ali Khan, Nasir Mehmood Khan, Juma Muhammad, Mazen Almehmadi, Osama Abdulaziz, Saad Alghamdi   +12 more
doaj   +1 more source

Donepezil + chromone + melatonin hybrids as promising agents for Alzheimer’s disease therapy

Journal of Enzyme Inhibition and Medicinal Chemistry, 2019
We describe herein the design, multicomponent synthesis and biological studies of new donepezil + chromone + melatonin hybrids as potential agents for Alzheimer’s disease (AD) therapy.
Irene Pachón-Angona, Bernard Refouvelet, Rudolf Andrýs, Helène Martin, Vincent Luzet, Isabel Iriepa, Ignacio Moraleda, Daniel Diez-Iriepa, María-Jesús Oset-Gasque, José Marco-Contelles, Kamil Musilek, Lhassane Ismaili   +11 more
doaj   +1 more source

Therapeutic Potentials of Microalgae in the Treatment of Alzheimer’s Disease

Molecules, 2017
Current research is geared towards the discovery of new compounds with strong neuroprotective potential and few or no side effects compared to synthetic drugs.
Tosin A. Olasehinde, Ademola O. Olaniran, Anthony I. Okoh   +2 more
doaj   +1 more source

Flavonoids as Prospective Neuroprotectants and Their Therapeutic Propensity in Aging Associated Neurological Disorders

Frontiers in Aging Neuroscience, 2019
Modern research has revealed that dietary consumption of flavonoids and flavonoids-rich foods significantly improve cognitive capabilities, inhibit or delay the senescence process and related neurodegenerative disorders including Alzheimer’s disease (AD).
Muhammad Ayaz, Abdul Sadiq, Muhammad Junaid, Muhammad Junaid, Farhat Ullah, Muhammad Ovais, Muhammad Ovais, Ikram Ullah, Jawad Ahmed, Muhammad Shahid   +9 more
doaj   +1 more source