Results 31 to 40 of about 12,590 (219)

Comparison of the cost‐effectiveness of a computer‐assisted learning program with a tutored demonstration to teach intestinal motility to medical students [PDF]

open access: yes, 1995
Computer‐based simulations of undergraduate experiments in pharmacology and physiology may offer a cost‐effective alternative to the traditional live laboratory for some students, for whom laboratory skills are less important.
Dewhurst, D. G., Leathard, H. L.
core   +2 more sources

Therapeutic Potentials of Microalgae in the Treatment of Alzheimer’s Disease

open access: yesMolecules, 2017
Current research is geared towards the discovery of new compounds with strong neuroprotective potential and few or no side effects compared to synthetic drugs.
Tosin A. Olasehinde   +2 more
doaj   +1 more source

Graminex pollen: phenolic pattern, colorimetric analysis and protective effects in immortalized prostate cells (PC3) and rat prostate challenged with LPS [PDF]

open access: yes, 2018
Prostatitis, a general term describing prostate inflammation, is a common disease that could be sustained by bacterial or non-bacterial infectious agents.
Brunetti, Luigi   +12 more
core   +2 more sources

New Multitarget Rivastigmine–Indole Hybrids as Potential Drug Candidates for Alzheimer’s Disease

open access: yesPharmaceutics
Alzheimer’s disease (AD) is the most common form of dementia with no cure so far, probably due to the complexity of this multifactorial disease with diverse processes associated with its origin and progress.
Leo Bon   +6 more
doaj   +1 more source

Anticholinesterase Activities of Different Solvent Extracts of Brewer’s Spent Grain

open access: yesFoods, 2021
Cholinesterases, involved in acetylcholine catabolism in the central and peripheral nervous system, have been strongly linked with neurodegenerative diseases. Current therapeutic approaches using synthetic drugs present several side effects. Hence, there
Rares I. Birsan   +3 more
doaj   +1 more source

Acetylcholinesterase Involvement in Apoptosis [PDF]

open access: yes, 2012
To date, more than 40 different types of cells from primary cultures or cell lines have shown AChE expression during apoptosis and after the induction apoptosis by different stimuli. It has been well-established that increased AChE expression or activity
Xue-Jun Zhang, David S. Greenberg
core   +2 more sources

Flavonoids as Prospective Neuroprotectants and Their Therapeutic Propensity in Aging Associated Neurological Disorders

open access: yesFrontiers in Aging Neuroscience, 2019
Modern research has revealed that dietary consumption of flavonoids and flavonoids-rich foods significantly improve cognitive capabilities, inhibit or delay the senescence process and related neurodegenerative disorders including Alzheimer’s disease (AD).
Muhammad Ayaz   +9 more
doaj   +1 more source

Nutraceutical Potential of Phenolics from ′Brava′ and ′Mansa′ Extra-Virgin Olive Oils on the Inhibition of Enzymes Associated to Neurodegenerative Disorders in Comparison with Those of ′Picual′ and ′Cornicabra′

open access: yesMolecules, 2018
The increasing interest in the Mediterranean diet is based on the protective effects against several diseases, including neurodegenerative disorders.
María Figueiredo-González   +5 more
doaj   +1 more source

A NeuroD1 AAV‐Based Gene Therapy for Functional Brain Repair in Alzheimer's Disease‐Like Non‐Human Primate Model

open access: yesAdvanced Science, EarlyView.
This study tests NeuroD1 AAV‐based gene therapy in a non‐human primate Alzheimer's disease model. The therapy prevents neuronal damage, inhibits hippocampal atrophy, and reduces neuroinflammation. It also repairs vascular and blood‐brain barrier damage, restores cerebrospinal fluid biomarkers, enhances hippocampal glucose metabolism, and improves ...
Zhouquan Jiang   +21 more
wiley   +1 more source

A Renal Clearable Probe for In Vivo Monoamine Oxidase (MAO) Detection

open access: yesAdvanced Science, EarlyView.
A renal‐clearable Cy7‐based fluorogenic probe enables rapid and non‐invasive detection of monoamine oxidase (MAO) activity in vivo. Upon MAO‐mediated activation, the fluorescent product is efficiently excreted in urine, allowing direct quantification of enzyme overexpression.
Marcia Domínguez   +13 more
wiley   +1 more source

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