Results 31 to 40 of about 118 (116)

Cholinesterase in osteosarcoma

Clinical Cancer Investigation Journal, 2012
Background: Several biochemical markers have been proposed to have diagnostic and prognostic value in the management of osteosarcoma. Cholinesterase affects cell proliferation, differentiation and responses to various insults, including stress, and might have functional role in bone tissues. Status of serum cholinesterase levels in osteosarcoma is not
Zile Singh Kundu, Simmi Kharb, Sandeep Kumar   +2 more
openaire   +2 more sources

Subcutaneous Foslevodopa as Novel Rescue Therapy for Akinetic Crisis in Parkinson's Disease: A Case Report

Movement Disorders Clinical Practice, EarlyView.
Bendix Labeit, Julius Schulten, Alfons Schnitzler, Christian Johannes Hartmann   +3 more
wiley   +1 more source

Semaglutide to remodel mitochondrial dynamics and mitophagy balance for vascular dementia therapy

VIEW, EarlyView.
The effects of semaglutide on IR, mitochondrial dynamics, and mitophagy in the hippocampus of BCAS mice after CCH. It was shown that semaglutide maintained the balance of mitochondrial dynamics and mitophagy by improving IR and passing through GLP‐1R/PI3K/Akt pathway, reduced hippocampal neuroinflammation and neuron loss, and thus promoted the recovery
Xiaoyan Yang, Peng Feng, Hongxu Zhu, Mingkang Wang, Nan Li, Bo Bai, Yuxiang Sun, Zhongrui Yan, Wenshi Wei, Jie Chang, Christian Hölscher, Wenxian Du   +11 more
wiley   +1 more source

Sarcopenia With High Subcutaneous Fat Predicts Metabolic Dysfunction Associated Steatotic Liver Disease Development After Pylorus Preserving Pancreaticoduodenectomy

World Journal of Surgery, EarlyView.
MASLD after PPPD affects not only the long‐term prognosis but also the availability of postoperative adjuvant chemotherapy, its prevention and treatment are important issues. The aim of this study is to analyze whether objective preoperative factors could predict the development of postoperative MASLD in patients after PPPD.
Masashi Nakagawa, Naokazu Chiba, Shigeto Ochiai, Takahiro Gunji, Toru Sano, Koichi Tomita, Masatoshi Shigoka, Satoshi Tabuchi, Eiji Hidaka, Shigeyuki Kawachi   +9 more
wiley   +1 more source

Effects of sodium fluoride on serum concentrations of selected psychotropic drugs

Journal of Forensic Sciences, EarlyView.
Abstract Caution is imperative when interpreting drug concentrations in blood, plasma, or serum, given the potential variance in the distribution of a compound across these fluids. Preservatives, such as sodium fluoride, prove beneficial in preventing drug degradation in collected blood samples. This study aimed to examine the impact of sodium fluoride
Jennifer Liut, Julian Prangenberg, Michael Krämer, Alexandra Maas‐Gramlich, Peter Heese, Markus Banger, Burkard Madea   +6 more
wiley   +1 more source

Aging‐Associated Liver Sinusoidal Endothelial Cells Dysfunction Aggravates the Progression of Metabolic Dysfunction‐Associated Steatotic Liver Disease

Aging Cell, Volume 24, Issue 5, May 2025.
Aged rats and human are more susceptible to MASLD‐related liver injury, steatosis, and fibrosis, accompanied by worsening of endothelial dysfunction. The SIRT1/p‐eNOS/NO pathway is involved in aggravated MASLD caused by aging‐related LSECs dysfunction.
Qingqing Dai, Quratul Ain, Navodita Seth, Hongchuan Zhao, Michael Rooney, Alexander Zipprich   +5 more
wiley   +1 more source

Altered immune response is associated with sex difference in vulnerability to Alzheimer's disease in human prefrontal cortex

Brain Pathology, Volume 35, Issue 3, May 2025.
This study analyzes four public transcriptome datasets from AD patients and age‐matched controls, revealing that the transcriptomic profile in female controls closely resembles that of AD patients. We identified a co‐expressed gene module associated with AD, sex, and aging, enriched with immune‐related functions.
Huiying Wen, Youzhe He, Yuanchun Tang, Langjian Zhu, Quyuan Tao, Bufan Jin, Ting Luo, Yujie Peng, Yanrong Wei, Junjie Lei, Lifang Wang, Fan Wang, Fei Ling, Yue Gao, Lei Han   +14 more
wiley   +1 more source

Measuring What Matters in Parkinson's Disease Research and Dysphagia: The Need for Core Outcome Sets

Movement Disorders, EarlyView.
Margaret Walshe, Julia Hirschwald, Tobias Warnecke   +2 more
wiley   +1 more source

Approach to the Management of Gastrointestinal Manifestations in Patients With Phaeochromocytoma and Paraganglioma

Clinical Endocrinology, EarlyView.
ABSTRACT Objective Managing gastrointestinal symptoms in patients with phaeochromocytoma and paraganglioma (PPGL) is challenging due to the risk of catecholaminergic crisis with many commonly prescribed medications, especially in functional tumours.
Monica Majumder, Cherie Chiang, Grace Kong, Michael Michael, Nirupa Sachithanandan, Emma Boehm   +5 more
wiley   +1 more source

The Application of Polymeric Nanoparticles as Drug Delivery Carriers to Cells in Neurodegenerative Diseases

Cell Proliferation, EarlyView.
Polymeric nanoparticles represent promising drug (gene) delivery carriers to the brain due to their unique advantages to facilitate the penetration of blood–brain barrier and endocytosis of neuronal cells in neurodegenerative diseases. ABSTRACT In spite of great advances in modern medicine, there are a few effective strategies for the treatment of ...
Lian Jin, Libo Nie, Yan Deng, Ghulam Jilany Khana, Nongyue He   +4 more
wiley   +1 more source