Results 51 to 60 of about 118 (116)
Basic &Clinical Pharmacology &Toxicology, Volume 137, Issue 1, July 2025.ABSTRACT The α7 nicotinic acetylcholine receptor (α7 nAChR) has emerged as a key target for treating cognitive dysfunction in neurological disorders such as Alzheimer's disease (AD) and schizophrenia. α7 nAChRs play essential roles in neurotransmission, neuroinflammation and synaptic plasticity, not only in neurons but also in glial cells, where they ...
Janus H. Magnussen
wiley +1 more source
Biomedical Chromatography, Volume 39, Issue 6, June 2025.ABSTRACT Methylene blue (MB), a phenothiazine derivative, is currently under clinical trials for Alzheimer's disease (AD) due to its potential to inhibit tau aggregation, a key pathological process in AD. In this study, we developed and qualified a rapid and reliable liquid chromatography‐quadrupole time‐of‐flight mass spectrometry (LC‐qTOF‐MS) method ...
Seo‐jin Park +5 more
wiley +1 more source
Light Sensitivity in Myasthenia Gravis: Clinical Characteristics and Impact on Quality of Life
Muscle &Nerve, Volume 71, Issue 6, Page 1081-1085, June 2025.ABSTRACT Introduction/Aims Light sensitivity is occasionally reported in myasthenia gravis patients, yet its prevalence, clinical characteristics, and impact on disease severity and quality of life remain insufficiently explored. This study aimed to evaluate the frequency, clinical characteristics, and the correlation of light sensitivity with ...
Eleonora Sabatelli +7 more
wiley +1 more source
Underdiagnosis of dementia in residents of residential aged care services: A scoping review
Australasian Journal on Ageing, Volume 44, Issue 2, June 2025.Abstract Objective Dementia is a leading cause of disability, dependence and death worldwide. Timely diagnosis and management of dementia are essential in the community and residential aged care services (RACS) or nursing homes. Underdiagnosis of dementia in RACS may negatively impact the quality of care, resulting in adverse health outcomes. Hence the
Reena Tewari +3 more
wiley +1 more source
A Short Story Changed How I Care for Persons Living With Dementia
Journal of the American Geriatrics Society, EarlyView.
Jason Karlawish
wiley +1 more source
EDIS, 2009 PI221, a 4-page fact sheet by Frederick M. Fishel, describes cholinesterase, as well as how several pesticides in different pesticide families can affect cholinesterase levels in humans, and the importance of timely monitoring of cholinesterase levels for any who handle organophosphate or carbamate pesticides, which inhibit cholinesterase.
openaire +3 more sources
Humility and Medicine, Lessons Learned: Perhaps the Fifth Ethics Principle
Journal of the American Geriatrics Society, EarlyView.
Michael Gordon
wiley +1 more source