Results 51 to 60 of about 27,370 (335)

FTIR Characterization and Bioactivity Assessment of Cinnamomum camphora Essential Oil: Antioxidant, Anti‐Enzymatic, and Antifungal Properties Against Phytopathogens

Chemistry &Biodiversity, EarlyView.
Essential oil from Cinnamomum camphora leaves: Chemical profiling using FTIR analysis and bioactivity assessment for diverse bio‐pharmaceutical applications. ABSTRACT This study explores key biopharmaceutical properties of Cinnamomum camphora essential oil (EO), including antioxidant, anti‐enzymatic, and antifungal activities, and evaluates its minimum
Maroua Cheribot Cherif, Hicham Boughendjioua, Lucia Caputo, Ippolito Camele, Tarek Tahraoui, Vincenzo De Feo, Hazem S. Elshafie   +6 more
wiley   +1 more source

Homomeric and Heteromeric Aβ Species Exist in Human Brain and CSF Regardless of Alzheimer’s Disease Status and Risk Genotype

Frontiers in Molecular Neuroscience, 2019
Background: A fundamental question in Alzheimer’s disease (AD) is whether amyloid-β (Aβ) peptides and their deposition in the brain signify a direct pathological role or they are mere outcome of the disease pathophysiological events affecting neuronal ...
Erica Lana, Anna Gellerbring, Sabrina Jung, Agneta Nordberg, Agneta Nordberg, Christina Unger Lithner, Taher Darreh-Shori   +6 more
doaj   +1 more source

Bis (Diamines) Cu and Zn Complexes of Flurbiprofen as Potential Cholinesterase Inhibitors: In Vitro Studies and Docking Simulations

Crystals, 2021
Alzheimer’s disease (AD) causes dementia and continuous damage to brain cells. Cholinesterase inhibitors can alleviate the condition by increasing communication between the nerve cells and reducing the risk of dementia.
Muhammad Jamil, Nargis Sultana, Rizwan Ashraf, Maryam Bashir, Muhammad Fayyaz ur Rehman, Fariha Kanwal, Humna Ellahi, Changrui Lu, Wei Xing Zhang, Muhammad Ilyas Tariq   +9 more
doaj   +1 more source

Assay optimisation and age-related baseline variation in biochemical markers in lesser black-backed gulls [PDF]

, 2019
Free-ranging animals are often used as bioindicators of both short- and long-term changes in ecosystem health, mainly to detect the presence and effects of contaminants.
Andrade Dos Santos, Cátia Sofia, De Neve, Liesbeth, Lens, Luc, Loureiro, Susana, Monteiro, Marta S, Mueller, Wendt, Sotillo, Alejandro, Stienen, Eric WM   +7 more
core   +1 more source

Bioequivalence of a Donepezil/Memantine 10/20 mg Fixed‐Dose Combination Versus Single‐Component Tablets in Healthy Korean Males

Clinical Pharmacology in Drug Development, EarlyView.
Abstract A fixed‐dose combination (FDC) tablet formulation of donepezil/memantine (10/20 mg) was developed to improve medication compliance in patients with Alzheimer's disease (AD). This study compared the pharmacokinetic (PK) characteristics and safety profiles of an FDC formulation (donepezil/memantine [10/20 mg]) and single components (SCs) of ...
Minkyu Choi, Byung Hak Jin, Do Hoon Keum, Kyoung Hoon Mo, Min Soo Park, Juhwan Lee, Sungjin Park, Choon Ok Kim   +7 more
wiley   +1 more source

Anticholinesterase and Serotoninergic Evaluation of Benzimidazole–Carboxamides as Potential Multifunctional Agents for the Treatment of Alzheimer’s Disease

Pharmaceutics, 2023
The etiology and pathogenesis of Alzheimer’s disease are multifactorial, so one of the treatment strategies is the development of the drugs that affect several targets associated with the pathogenesis of the disease.
Daria A. Belinskaia, Polina A. Voronina, Denis V. Krivorotov, Richard O. Jenkins, Nikolay V. Goncharov   +4 more
doaj   +1 more source

Cholinesterase inhibitors for delirium [PDF]

Cochrane Database of Systematic Reviews, 2005
Delirium is now the preferred term to describe acute confusional states. It is experienced by 10 to 30% of all hospital inpatients. Delirium is potentially reversible and is related to several adverse outcomes, including increased hospital length of stay, poor functional status, persistent cognitive impairment, need for institutional care and probably ...
Ross Overshott, Salman Karim, Alistair Burns   +2 more
openaire   +3 more sources

Examination of effectiveness of chemical scavengers as therapeutics in organophosphate poisoning [PDF]

, 2017
Cholinergic crisis triggered by inhibition of cholinesterases via organophosphorus nerve agents (OP) and pesticides is treated with atropine and a reactivator of inhibited cholinesterase, called oxime.
Bierwisch, Anne
core  

Graminex pollen: phenolic pattern, colorimetric analysis and protective effects in immortalized prostate cells (PC3) and rat prostate challenged with LPS [PDF]

, 2018
Prostatitis, a general term describing prostate inflammation, is a common disease that could be sustained by bacterial or non-bacterial infectious agents.
Brunetti, Luigi, Carradori, Simone, Cesa, Stefania, Chiavaroli, Annalisa, Ferrante, Claudio, Leone, Sheila, Leporini, Lidia, Locatelli, Marcello, Macchione, Nicola, Menghini, Luigi, Orlando, Giustino, Recinella, Lucia, Zengin, Gokhan   +12 more
core   +2 more sources

Connecting the dots: A narrative review of the relationship between heart failure and cognitive impairment

ESC Heart Failure, Volume 12, Issue 2, Page 1119-1131, April 2025.
Abstract Large clinical data underscore that heart failure is independently associated to an increased risk of negative cognitive outcome and dementia. Emerging evidence suggests that cerebral hypoperfusion, stemming from reduced cardiac output and vascular pathology, may contribute to the largely overlapping vascular dementia and Alzheimer's disease ...
Mauro Massussi, Maria Giulia Bellicini, Marianna Adamo, Andrea Pilotto, Marco Metra, Alessandro Padovani, Riccardo Proietti   +6 more
wiley   +1 more source