Results 71 to 80 of about 27,370 (335)

Progress of non‐motor symptoms in early‐onset Parkinson's disease

Ibrain, EarlyView.
This study reviews the research progress related to non‐motor symptoms (NMS) in patients with early onset Parkinson's disease (EOPD), including neuropsychiatric symptoms, autonomic dysfunction, sleep disorders, and sensory disorders and also summarizes the characteristics of NMS in the genetic form of Parkinson's disease (PD).
Fanshi Zhang, Aidi Luo, Shusheng Liao, Mei Liu, Jun Zhang, Zucai Xu   +5 more
wiley   +1 more source

Fototermičke bioanalitičke metode za testiranje toksičnosti pesticida [PDF]

, 2003
This paper describes bioanalytical methods and biosensors which rely on cholinesterase (ChE) inhibition and can be used to detect and test the toxicity of organophosphate (OP) and carbamate pesticides. Particular attention is given to the combined use of
Lea Pogačnik, Mladen Franko
core   +1 more source

Nerve Agent Hydrolysis Activity Designed into a Human Drug Metabolism Enzyme [PDF]

, 2010
Organophosphorus (OP) nerve agents are potent suicide inhibitors of the essential neurotransmitter-regulating enzyme acetylcholinesterase. Due to their acute toxicity, there is significant interest in developing effective countermeasures to OP ...
Andrew C. Hemmert, C. Linn Cadieux, Carol C. Edwards, Douglas M. Cerasoli, Fernando Rodrigues-Lima, John R. Cashman, Jonathan S. Edwards, Lyudmila Tsurkan, Matthew R. Redinbo, Monika Wierdl, Philip M. Potter, Roberto A. Chica, Shane A. Kasten, Stephen L. Mayo, Steven M. Lewis, Tamara C. Otto   +15 more
core   +6 more sources

Perinatal Exposure to the Neonicotinoid Thiacloprid Impacts Transcription of Neuroplasticity and Neuroendocrine Markers in Mice but Not in the Zebrafish Model

Journal of Applied Toxicology, EarlyView.
ABSTRACT Neonicotinoids are widely used insecticides in agriculture, aquaculture, pet care, and urban pest control. Initially developed to selectively target the insect cholinergic system, their extensive use has raised concerns about adverse effects on nontarget vertebrates.
Kirthana Kunikullaya U, Zuzanna M. Baran, Pascal Coumailleau, Laetitia Guillot, Harry W. M. Steinbusch, Fatima Smagulova, Thierry D. Charlier   +6 more
wiley   +1 more source

Enhancing Biocide Safety of Milk Using Biosensors Based on Cholinesterase Inhibition

Biosensors
A sensitive and reliable electrochemical biosensor for the detection of benzalkonium chloride (BAC) and didecyldimethylammonium chloride (DDAC), the most commonly used disinfectant biocides in the agri-food industry, is described.
Lynn Mouawad, Georges Istamboulie, Gaëlle Catanante, Thierry Noguer   +3 more
doaj   +1 more source

Pyridostigmine as treatment for chronic gastrointestinal dysmotility in a child with Mowat‐Wilson syndrome: A case report and literature review

JPGN Reports, EarlyView.
Abstract Gastrointestinal dysmotility is commonly reported among patients with Mowat‐Wilson syndrome (MWS) and poses a significant symptomatic burden. Unfortunately, there remains a knowledge gap regarding effective treatment strategies. A 2‐year‐old male with MWS presented with chronic paradoxical abdominal pain, constipation, and progressively ...
Grace J. Lin, Shreya B. Kishore, Sally Samaan, Lisa S. Hackett, Kevan Jacobson, Gabriella Horvath   +5 more
wiley   +1 more source

Enantiomeri kinuklidin-3-ol derivata: Razdvajanje enantiomera i interakcija s ljudskim kolinesterazama [PDF]

, 2005
The (R)- and (S)-enantiomers of quinuclidin-3-ol and quinuclidin-3-yl acetate as well as their quaternary N-methyl and N-benzyl derivatives were synthesized in order to study the stereoselectivity of human erythrocyte acetylcholinesterase (EC 3.1.1.7 ...
Anita Bosak, Ines Primožić, Mislav Oršulić, Srdjanka Tomić, Vera Simeon-Rudolf   +4 more
core   +1 more source

Updating neuropathology and neuropharmacology of monoaminergic systems [PDF]

, 2016
PreprintNon peer ...
De Deurwaerdère, Philippe, Di Giovanni, Giuseppe, Ramsay, Rona R.   +2 more
core   +2 more sources

Effect of pH on Blepharisma intermedium. 5. Studies on esterases [PDF]

, 1977
Synopsis. Esterases of Blepharisma intermedium grown in buffered media of different pH values and in unbuffered media have been char­acterized. Selective inhibition studies indicate six carboxylesterases, two arylesterases and one cholinesterase in all ...
Jyothy, P.S., Shadaksharaswamy, M.
core  

Lewy Body Dementia Research in Latin America: A Scoping Review

Movement Disorders Clinical Practice, EarlyView.
Abstract Background Dementia research in Latin America (LA) has primarily focused on Alzheimer's Disease and Frontotemporal Dementia, while Lewy body dementia (LBD) has been largely forgotten. Objective We aimed to review the available evidence on LBD in LA, offering a comprehensive perspective for understanding the lack of reports and the unique ...
Carlos Cano‐Gutiérrez, Salomón Salazar‐Londoño, Felipe Botero‐Rodriguez, Salomón Páez‐García, Salomón Giraldo, José Manuel Santacruz‐Escudero, Dag Aarsland, Miguel Germán Borda, on behalf of COL‐DLB, Felipe Botero‐Rodriguez, Miguel Germán Borda, Omar Buritica, Catalina Cerquera‐Cleves, Maria Camila Gonzalez, Elkin Garcia‐Cifuentes, Alberto Jaramillo‐Jimenez, David Aguillon, Yamile Bocanegra, Beatriz Elena Munoz‐Ospina, Carlos Alberto Cano‐Gutierrez, Carlos Tobón, Hernando Santamaría‐García, José Manuel Santacruz‐Escudero, Dag Aarsland, Jorge Orozco, Salomon Salazar‐Londoño, Luis Carlos Venegas‐Sanabria, Salomón Páez‐García, Francisco Lopera, Juan Camilo Castro, Patrick Verhelst Forero, Alexandra Ferreiròs   +31 more
wiley   +1 more source