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Cholinesterases

2001
Publisher Summary This chapter discusses cholinesterases, their importance in understanding the toxicity of organophosphate ester (OP) and carbamate (CB) pesticides, and their application to risk assessment. Cholinesterases (ChEs) are specialized carboxylic ester hydrolases that break down esters of choline.
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Cholinesterase of Leucocytes

American Journal of Physiology-Legacy Content, 1955
By using the Michel's method specific cholinesterase was found in the leucocytes of man, dog and rabbit. The largest quantities were found in the leucocytes of rabbit, followed by that of man and lastly by that found in the dog. The pus cells do not contain cholinesterase.
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Cholinesterase and anaesthesia

Clinical Biochemistry, 1979
Summary There appear to be two genetic loci for cholinesterase, E 1 and E 2 . The first allele is closely linked with the transferrin locus and is probably on chromosome number 1. At the second (E 2 ) locus only one variant has been described. At the E 1 locus at least 4 alleles have been detected: the usual (E 1 u ), atypical (E 1 a ), fluoride ...
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Cholinesterases of neuromuscular junction

Neurochemistry International, 1980
The ultrastructural localization of AChE and BuChE was studied in motor endplates of the rat and mouse diaphragms, using the CNS(?) modification of the one-step Cu-thiocholine procedure. AChE activity was observed on pre- and postsynaptic membranes, in the basal lamina and in the Schwann cell-nerve terminal interspace.
Janez Sketelj   +3 more
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Cholinesterase Inhibitors and Beyond

Current Alzheimer Research, 2009
Cholinesterase inhibitors (ChEIs) were introduced in the therapy of Alzheimer Disease (AD) in the nineteen nineties with great expectations. The hopes and large interest raised by these drugs are well demonstrated by 12,000 references listed by PubMed under 'ChEI' for 1995-2007. The list is reduced to 2500 if we confine ourselves to 'ChEIs and dementia'
PEPEU, GIANCARLO   +1 more
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Cholinesterase Nevus: Cholinesterases in Pigmented Tumors of the Skin

Archives of Dermatology, 1960
One of the enigmas of modern cytology is the nevus cell. Its origin has been variously claimed to be from melanocytes, 1 from epidermal cells, 2 and from nerve cells, 3 and each source has been hotly debated. It has been thought to grow up into the skin 4 and also to form by "abtropfung" 5 from the epidermis down into the dermis.
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Cholinesterase inhibitors and memory

Chemico-Biological Interactions, 2010
A consensus exists that cholinesterase inhibitors (ChEIs) are efficacious for mild to moderate Alzheimer's Disease (AD). Unfortunately, the number of non-responders is large and the therapeutic effect is usually short-lasting. In experimental animals, ChEIs exert three main actions: inhibit cholinesterase (ChE), increase extracellular levels of brain ...
PEPEU, GIANCARLO   +1 more
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Cholinesterases and Cholinesterase Inhibitors

Current Enzyme Inhibition, 2008
Sarka Stepankova, Karel Komers
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Benzamides and cholinesterases.

Research communications in chemical pathology and pharmacology, 1987
At certain doses metoclopramide (MT), sulpiride and bromopride produce anti-cholinesterase effects as shown by studies on the serum and erythrocyte cholinesterases of the rabbit and the dog, and by those on the hypotensive effect of ACh incubated with rabbit serum in the presence or absence of MT. The anti-cholinesterase effect of MT was more intensive
VACCA C   +3 more
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Cholinesterase

Science, 1944
B, Mendel, H, Rudney
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