Results 151 to 160 of about 118,065 (344)

β‐Mangostin Attenuates TET2‐Mediated DNA Demethylation of Prkcg in the Prevention of Intervertebral Disc Degeneration

open access: yesAdvanced Science, EarlyView.
β‐Mangostin alleviates intervertebral disc degeneration through dual modulation of macrophage polarization and the TET2‐Prkcg axis in nucleus pulposus cells. Abstract Intervertebral disc degeneration (IDD) induced lower back pain is a main cause of disability, resulting in a substantial workforce loss worldwide and placing a substantial burden on the ...
Xiangzhen Kong   +15 more
wiley   +1 more source

Competitive Binding of Somatomedin to the Insulin Receptors of Adipocytes, Chondrocytes, and Liver Membranes

open access: green, 1972
Raymond L. Hintz   +3 more
openalex   +1 more source

BMSC‐NFMC Model for Vascular Regulation and Interface Integration in Osteochondral Regeneration

open access: yesAdvanced Science, EarlyView.
A novel strategy for integrated osteochondral tissue regeneration using BMSC‐NFMCs, this study has demonstrated the precise regulation of vascularization and effective interface integration using optimized nanofibrous materials and innovative construction methods.
Qian Zhou   +8 more
wiley   +1 more source

Advances in Medical Devices for Augmented Acupuncture Therapy

open access: yesAdvanced Science, EarlyView.
Traditional acupuncture therapy faces several challenges in clinical applications, such as complex operation procedures and prolonged therapeutic periods. By incorporating physical stimulations and drug delivery technologies, engineered acupuncture needles (EANs) can enhance therapeutic efficacy, improve patient compliance, as well as mitigate ...
Ruisi Cai   +7 more
wiley   +1 more source

Molten‐Salt‐Mediated Synthesis of Atomic Manganese/Cobalt Catalysts on Bioceramic Microparticles for Catalytic Anti‐Osteoarthritis Treatments

open access: yesAdvanced Science, EarlyView.
Microparticle‐based antioxidants capable of scavenging multiple reactive oxygen species (ROS) have been developed. When retained within the articular cavity of osteoarthritic mice, Mn‐ or Co‐AKT‐MPs protect the inherent homeostasis between cartilage anabolism and catabolism, and inhibit synovial inflammation.
Ronghui Deng   +11 more
wiley   +1 more source

Biosynthesis of proteoglycans by chick limb bud chondrocytes

open access: hybrid, 1978
S. De Luca   +2 more
openalex   +1 more source

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