Results 161 to 170 of about 76,519 (202)

Prevention of Chondrocyte Apoptosis

The Journal of Bone and Joint Surgery-American Volume, 2001
The occurrence of chondrocyte apoptosis may be cri­tical in determining the extent of a lesion and sub­sequent repair after mechanical injury to articular cartilage. Agents that prevent apoptosis and increase chondrocyte survival may prove beneficial in the treatment of these ­lesions.
D D, D'Lima, S, Hashimoto, P C, Chen, M K, Lotz, C W, Colwell   +4 more
openaire   +2 more sources

In situ chondrocyte viscoelasticity

Journal of Biomechanics, 2012
It has been proposed, based on theoretical considerations, that the strain rate-dependent viscoelastic response of cartilage reduces local tissue and cell deformations during cyclic compressions. However, experimental studies have not addressed the in situ viscoelastic response of chondrocytes under static and dynamic loading conditions. In particular,
Sang-Kuy, Han, Ryan, Madden, Ziad, Abusara, Walter, Herzog   +3 more
openaire   +2 more sources

Chondrocyte Proliferation and Differentiation

2011
The skeletal elements of the axial and appendicular skeleton are preformed as cartilage templates by a mechanism called endochondral ossification. During this process, a cartilage template is formed in which chondrocytes proliferate and differentiate into hypertrophic chondrocytes and are gradually replaced by bone.
Manuela, Wuelling, Andrea, Vortkamp
openaire   +2 more sources

Culture of Immortalized Chondrocytes and Their Use As Models of Chondrocyte Function

2004
Immortalization of chondrocytes increases life span and proliferative capacity but does not necessarily stabilize the differentiated phenotype. Expansion of chondrocyte cell lines in continuous monolayer culture may result in the loss of phenotype, particularly if high cell density is not maintained. This chapter describes strategies for maintaining or
openaire   +2 more sources

Targeting regulated chondrocyte death in osteoarthritis therapy

Biochemical Pharmacology, 2023
Wei Hu, Renpeng Zhou
exaly  

The Role of Chondrocyte Hypertrophy and Senescence in Osteoarthritis Initiation and Progression

International Journal of Molecular Sciences, 2020
Yeri Alice Rim, Ji Hyeon Ju, Yoojun Nam
exaly  

Chondrocytes

2000
Tariq M. Haqqi, Donald D. Anthony, Charles J. Malemud   +2 more
openaire   +1 more source

Chondrocyte hypertrophy and osteoarthritis: role in initiation and progression of cartilage degeneration?

Osteoarthritis and Cartilage, 2012
W B van den Berg
exaly  

Chondrocyte Apoptosis in the Pathogenesis of Osteoarthritis

International Journal of Molecular Sciences, 2015
Hyun Ah Kim
exaly  

Chondrocytes

2021
openaire   +1 more source