Results 181 to 190 of about 97,625 (307)

[Retracted] Role of miR‑146a in human chondrocyte apoptosis in response to mechanical pressure injury <i>in vitro</i>. [PDF]

Int J Mol Med
Jin L, Zhao J, Jing W, Yan S, Wang X, Xiao C, Ma B.   +6 more
europepmc   +1 more source

Microfracture for full‐thickness chondral lesions of the knee in elite athletes leads to high return‐to‐play rates

Knee Surgery, Sports Traumatology, Arthroscopy, EarlyView.
Abstract Purpose Injuries to the knee are common in elite athletes and often involve damage to the articular cartilage. Given the high demands of elite sport, full‐thickness articular cartilage defects in the knee can be career‐limiting or threatening.
David J. Haslhofer, Jobe Shatrov, Mary Jones, Wahid Abdul, Arman Motesharei, Simon V. Ball, Andy Williams   +6 more
wiley   +1 more source

Mitochondrial transplantation for osteoarthritis: from molecular mechanisms to clinical translation. [PDF]

Front Immunol
Liu Y, Liu Y, Zhang N, An H, Mi L, Gao Y, Xu K.   +6 more
europepmc   +1 more source

MOCART 2.0 score of 60 or greater measured at 1 year post‐operatively predicts favourable clinical outcomes after surgical repair of tibiofemoral cartilage lesions

Knee Surgery, Sports Traumatology, Arthroscopy, EarlyView.
Abstract Purpose (1) To evaluate the relationship between the Magnetic Resonance Observation of Cartilage Repair Tissue (MOCART) 2.0 score and post‐operative clinical outcomes following surgical repair of cartilage lesions in the tibiofemoral joint, and (2) to determine threshold values of the 1‐year MOCART 2.0 score associated with favourable patient ...
Hyun‐Soo Moon, Sungjun Kim, Chong‐Hyuk Choi, Min Jung, Kwangho Chung, Se‐Han Jung, Jin‐Gyu Kim, Min‐Cheol Park, Sung‐Hwan Kim   +8 more
wiley   +1 more source

Targeting EFEMP1 enhances chondrogenesis and inhibits hypertrophic differentiation in a spontaneous osteoarthritis mouse model. [PDF]

J Mol Med (Berl)
Chang Y, Jiang PH, Hsu YH, Lin YC, Hu CC, Li YZ, Ueng SW, Chen MF.   +7 more
europepmc   +1 more source

Spheroid‐based matrix‐induced autologous chondrocyte implantation combined with autologous bone grafting restores physiological cartilage and subchondral bone properties in osteochondral knee defects ‐ An MRI‐based analysis

Knee Surgery, Sports Traumatology, Arthroscopy, EarlyView.
Abstract Purpose This study aimed to evaluate the radiological and patient‐reported outcome measures (PROMs) following spheroid‐based matrix‐induced autologous chondrocyte implantation combined with autologous bone grafting (MABCI) for the treatment of osteochondral defects of the knee.
Stephan Oehme, Benjamin Bartek, Janne Callsen, Jessica Schallock, Tobias Winkler, Thorsten Diekhoff, Tobias Jung, Danko Dan Milinkovic   +7 more
wiley   +1 more source

Menstrual blood-derived mesenchymal stromal cell extracellular vesicles stimulate chondrocytes and cartilage extracellular matrix synthesis in vitro. [PDF]

Sci Rep
Kugaudaite G, Bakutyte I, Bagdonas E, Vaiciuleviciute R, Talaikis M, Miksiunas R, Lebedis I, Pachaleva J, Kvederas G, Krugly E, Bernotiene E, Uzieliene I.   +11 more
europepmc   +1 more source

Autologous minimally manipulated adipose‐derived stromal vascular fraction in knee osteoarthritis: Lasting symptom relief and imaging evidence from a 12‐month prospective study

Knee Surgery, Sports Traumatology, Arthroscopy, EarlyView.
Abstract Purpose To evaluate the safety and efficacy of intra‐articular autologous transplantation of adipose‐derived connective tissue micrografts rich in stromal vascular fraction (CTM‐SVF), obtained using an enzyme‐free system (Hy‐Tissue® SVF) for knee osteoarthritis (OA). Methods Thirty patients (mean age of 53.3 ± 6.4 years) with Kellgren–Lawrence
Laura Mangiavini, Nicolò Rossi, Riccardo Giorgino, Francesco Borelli, Alessandra Colombini, Paola De Luca, Simona Landoni, Luca Maria Sconfienza, Carmelo Messina, Irene Beriotto, Giuseppe M. Peretti, Laura de Girolamo   +11 more
wiley   +1 more source

Osteoarthritis: Epidemiology, Pathogenesis, and Treatment. [PDF]

MedComm (2020)
Chen T, Chen W, Xu T, Wang H, Zhang Y, Wang L, Zhu S, Tao H, Yang X.   +8 more
europepmc   +1 more source

Minced cartilage implantation provides comparable outcomes to autologous chondrocyte implantation (ACI) for knee cartilage lesions: A matched‐pair analysis

Knee Surgery, Sports Traumatology, Arthroscopy, EarlyView.
Abstract Purpose To compare short‐term patient‐reported outcomes (PROMs) and revision rates between autologous hand‐minced cartilage implantation (MCI) and autologous chondrocyte implantation (ACI) for knee cartilage lesions. Methods All patients undergoing MCI or ACI at a single centre were retrospectively analysed from a prospectively maintained ...
Armin Runer, Louis Leuthard, Luisa Hoheisel, Vincent A. Stadelmann, Stefan Preiss, Gian M. Salzmann, Jakob Hax   +6 more
wiley   +1 more source