Dynamics of postnatal bone development and epiphyseal synostosis in the caprine autopod
Abstract Background Bones develop to structurally balance strength and mobility. Bone developmental dynamics are influenced by whether an animal is ambulatory at birth. Precocial species, which are ambulatory at birth, develop advanced skeletal maturity in utero and experience postnatal development under mechanical loading.
Christopher J. Panebianco +8 more
wiley +1 more source
The Influence of Sirtuin 6 on Chondrocyte Senescence in Osteoarthritis Under Aging: Focusing on Mitochondrial Dysfunction and Oxidative Stress. [PDF]
Zhao H, Wu W.
europepmc +1 more source
Modulation of Hyaluronan Synthesis by the Interaction between Mesenchymal Stem Cells and Osteoarthritic Chondrocytes [PDF]
Eliane Antonioli +5 more
openalex +1 more source
Abstract Trichorhinophalangeal syndrome (TRPS) is a rare genetic disease inherited in an autosomal dominant manner. It occurs in 1 in 100,000 people globally and is caused by several types of mutations of the TRPS1 gene. Since the first human patient was reported in 1966, typical and atypical pathologies, disease courses, and treatment case ...
Naoya Saeki +6 more
wiley +1 more source
Kazald1 attenuates chondrocyte fibrosis to potentiate hyaline cartilage regeneration by interfering with the pro-fibrotic TGF-β signaling. [PDF]
Zhu Y +7 more
europepmc +1 more source
Accelerated hypertrophic chondrocyte kinetics in GDF‐7 deficient murine tibial growth plates [PDF]
Borjana Mikic +3 more
openalex +1 more source
The role of cytokines in ovarian cancer drug resistance
Abstract Ovarian cancer is the leading cause of death among women diagnosed with female reproductive system cancers. While significant advances have been made in treating various types of cancer, progress in ovarian cancer treatment over the past 20 years has been minimal, and the treatment course of ovarian cancer is not linear. Although many patients
Lu Wang +7 more
wiley +1 more source
Optimizing LED photobiomodulation parameters to prevent cartilage matrix degradation in knee osteoarthritis: in vitro and in vivo study. [PDF]
Fan T +5 more
europepmc +1 more source
Stigmasterol attenuates atherosclerosis by inhibiting inflammatory signaling and foam cell formation
Stigmasterol mitigates atherosclerotic plaque formation by modulating foam cell phenotypic alterations and cholesterol metabolism. Stigmasterol inhibits inflammatory CD86+ macrophage polarization via the NF‐κB/NLRP3 pathway and downregulates CD68 expression in smooth muscle cells (SMCs), contributing to reduced vascular inflammation.
Baiyi Lu +10 more
wiley +1 more source

