Results 261 to 270 of about 156,620 (407)

Mitochondrial dysfunction: Related diseases, influencing factors, and detection

Interdisciplinary Medicine, EarlyView.
Mitochondrial dysfunction is implicated in the pathogenesis of numerous diseases, including neurological disorders, cancers, and cardiovascular conditions, through mechanisms such as mitochondrial DNA mutations, dysregulation of mitochondrial network dynamics, and impaired mitophagy.
Zhaojin Li, Shiyu Li, Wanying Chen, Ziyu Zhang, Chun Pan, Peng Lei, Cheng Cheng, Junyou Zhu, Hanxiao Sun, Zhenning Dai   +9 more
wiley   +1 more source

Evaluation of potassium pyroantimonate/sucrose/glutaraldehyde concentration and incubation time as essential variables for localizing calcium bound to organic compounds in epiphyseal chondrocytes. [PDF]

, 1984
Herbert K. Kashiwa, N J Thiersch
openalex   +1 more source

Atf3 + senescent chondrocytes mediate meniscus degeneration in aging. [PDF]

Arthritis Res Ther
Wang JY, Liu YH, Wang X, Ma M, Pan ZY, Fan AY, Lu LY, Liu Z, Tao K, Yin F.   +9 more
europepmc   +1 more source

Organoid‐tissue extracellular vesicles

Interdisciplinary Medicine, EarlyView.
Abstract Extracellular vesicles (EVs) are lipid bilayer structures secreted by cells that act as intercellular messengers. Tissue‐derived EVs (TEVs), harvested from the tissue interstitium, directly reflect the actual physiological or pathological state of the tissue microenvironment.
Han Liu, Ting Cheng, Guangfeng Li, Zhidao Xia, Chenglong Wang, Ke Xu, Jiacan Su   +6 more
wiley   +1 more source

Direct Effects of 1,25-Dihydroxyvitamin D₃and 24,25-Dihydroxyvitamin D3 on Growth Zone and Resting Zone Chondrocyte Membrane Alkaline Phosphatase and Phospholipase-A2 Specific Activities*

, 1988
Zvi Schwartz, DIXIE L. SCHLADER, L.D. Swain, Barbara D. Boyan   +3 more
openalex   +1 more source

MiR-335-5p Escaped from CircKIAA0586 Adsorption Contributes to Mechanical Overloading-Induced Cartilage Degeneration by Targeting Lymphoid-Specific Helicase. [PDF]

Research (Wash D C)
Xie H, Lu Y, Pan J, Zeng H, Zhang Z, Yin J, Zhu J, Luo B, Guo D, Wu C, Zeng C, Shao Y, Bai X, Cai D, Zhang H.   +14 more
europepmc   +1 more source

Impacts of Inorganic Arsenic Exposure on Genetic Stability of Human Mesenchymal Stromal Cells

Journal of Applied Toxicology, EarlyView.
ABSTRACT Human mesenchymal stem/stromal cells (hMSCs) can differentiate into mesoderm‐type cells, making them suitable candidates for tissue repair therapies. However, their relatively low frequency in adult tissue necessitates ex vivo expansion prior to regenerative medicine applications, and therefore, long‐term hMSC genetic stability during ...
Marc A. Beal, Melanie Coughlan, Andrée Nunnikhoven, Reena Corbane, Cathy Cummings‐Lorbetskie, Andrea Rowan‐Carroll, Tanvi Sharma, Andrew Williams, Jessie R. Lavoie, Andrew Stalker, Asish Mohapatra, Matthew J. Meier   +11 more
wiley   +1 more source

97 HUMAN FETAL AND ADULT CHONDROCYTES: CLONAL GROWTH PROMOTION BY INSULIN LIKE GROWTH FACTORS I AND II, INSULIN AND GROWTH HORMONE [PDF]

, 1985
U. Vetter, J Zapf, W. Heit, Gerd Helbinq, E. Heinze, R Froesch, W. Teller   +6 more
openalex   +1 more source

A Cartilaginous Organoid System Derived From Human Expanded Pluripotent Stem Cells (hEPSCs). [PDF]

Bio Protoc
Wang H, Qiu J, Lin Y, Bai X, Wei X.
europepmc   +1 more source

Association of UCMA With Cartilage Pathogenesis and Inflammation in Patients With Rheumatoid Arthritis: A Novel Biomarker

Journal of Clinical Laboratory Analysis, EarlyView.
The study of 98 RA patients and 24 healthy controls found significantly higher serum levels of UCMA, COMP, TNF‐α, and IL‐6 in RA patients. ROC curve analysis showed that these markers could differentiate RA from healthy controls. UCMA correlates with inflammation and cartilage degeneration, suggesting its potential as a diagnostic marker.
Münteha Nur Sonuç Karaboğa, Hamza Malik Okuyan, Serdar Dogan, Hamdi Oguzman, Gezmiş Kimyon   +4 more
wiley   +1 more source