Results 21 to 30 of about 131,500 (355)
Biomedicines, 2023 In osteoarthritis (OA), the articular cartilage covering the articular surface of the bone wears out, exposing the subchondral bone, and the synovial membrane surrounding the joint becomes inflamed, causing pain and deformity.
Hun Hwan Kim +11 more
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Artificial Cells, Nanomedicine, and Biotechnology, 2019 The medical community has expressed significant interest in the treatment of cartilage defect. Successful repair of articular cartilage defects remains a challenge in clinics. Due to the huge advantages of 3D micro/nanomaterials, 3D artificial micro/nano
Shuai Wu +8 more
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Autoimmunity, 2021 Long non-coding RNAs (lncRNAs) play a part in a wide variety of diseases, including osteoarthritis (OA). This study was designed to investigate the biological role of lncRNA LINC00265 in OA and its underlying mechanisms.
Hanlin Zou, Chunde Lu, Jianjun Qiu
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Optimization of Sturgeon Cartilage Products and Its Regulation on Human Chondrocyte Inflammation
Shipin gongye ke-ji, 2022 The purpose of this paper was to prepare a sturgeon cartilage product from sturgeon cartilage and explore its effect on inflammation of human chondrocytes.
Hengge LIU +6 more
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Cell Reports, 2016 Hippo signaling controls organ size and tissue regeneration in many organs, but its roles in chondrocyte differentiation and bone repair remain elusive. Here, we demonstrate that Yap1, an effector of Hippo pathway inhibits skeletal development, postnatal
Yujie Deng +6 more
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The Elusive Origin of Atherosclerotic Plaque Calcification
Frontiers in Cell and Developmental Biology, 2021 It has been known for decades or even centuries that arteries calcify as they age. Vascular calcification probably affects all adults, since virtually all have atherosclerotic plaques: an accumulation of lipids, inflammatory cells, necrotic debris, and ...
Emmanuelle Canet-Soulas +4 more
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A Preliminary Study of Human Amniotic Membrane as a Potential Chondrocyte Carrier [PDF]
Malaysian Orthopaedic Journal, 2009 PURPOSE: To investigate the feasibility of using processed human amniotic membrane (HAM) to support the attachment and proliferation of chondrocytes in vitro which in turn can be utilised as a cell delivery vehicle in tissue engineering applications.
L Boo +5 more
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Frontiers in Pharmacology, 2021 Osteoarthritis (OA) is the most prevalent joint disease worldwide, making it a major cause of pain and disability. Identified as a chronic and progressive disease, effective treatment at the early stages of OA has become critical to its management ...
Chenyang Zhuang +6 more
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Autologous Chondrocyte Implantation [PDF]
JBJS Essential Surgical Techniques, 2016 Autologous chondrocyte implantation (ACI) for the treatment of articular cartilage lesions of the knee joint provides successful and durable long-term outcomes.Obtain standing radiographs and magnetic resonance imaging (MRI) scans to identify all associated abnormalities (background factors).Evaluate the knee joint systematically and harvest cartilage ...
Tom, Minas, Takahiro, Ogura, Tim, Bryant
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The role of TGF-β2 in cartilage development and diseases
Bone & Joint Research, 2021 Transforming growth factor-beta2 (TGF-β2) is recognized as a versatile cytokine that plays a vital role in regulation of joint development, homeostasis, and diseases, but its role as a biological mechanism is understood far less than that of its ...
Mengmeng Duan +3 more
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