Results 21 to 30 of about 129,913 (308)

A Preliminary Study of Human Amniotic Membrane as a Potential Chondrocyte Carrier [PDF]

open access: yesMalaysian Orthopaedic Journal, 2009
PURPOSE: To investigate the feasibility of using processed human amniotic membrane (HAM) to support the attachment and proliferation of chondrocytes in vitro which in turn can be utilised as a cell delivery vehicle in tissue engineering applications.
L Boo   +5 more
doaj  

Hsa_circ_0005567 Activates Autophagy and Suppresses IL-1β-Induced Chondrocyte Apoptosis by Regulating miR-495

open access: yesFrontiers in Molecular Biosciences, 2020
Excessive chondrocyte apoptosis is mostly responsible for the progression of osteoarthritis (OA). It has been shown that circular RNAs (circRNAs) are differentially expressed in OA cartilage and participate in various pathological processes during OA ...
Jinling Zhang   +4 more
doaj   +1 more source

Development of Anti-OSCAR Antibodies for the Treatment of Osteoarthritis

open access: yesBiomedicines, 2023
Osteoarthritis (OA) is the most common joint disease that causes local inflammation and pain, significantly reducing the quality of life and normal social activities of patients.
Gyeong Min Kim   +8 more
doaj   +1 more source

Ochronotic Chondropathy: A Case Report

open access: yesBiomedicines, 2023
Endogenous ochronosis, also known as alkaptonuria, is a rare disease known for its bluish-black discoloration of the skin, sclerae, and pinnae, as well as urine that turns black upon standing.
Jake Littman   +4 more
doaj   +1 more source

Novel Heredity Basis of the Four-Horn Phenotype in Sheep Using Genome-Wide Sequence Data

open access: yesAnimals, 2023
Horns are an important breeding trait for sheep. However, no widely recognized viewpoint on the regulatory genes and mechanisms of horns is available, and the genetic basis of the four-horn phenotype (FHP) is unclear.
Haoyuan Zhang   +10 more
doaj   +1 more source

Potential Joint Protective and Anti-Inflammatory Effects of Integrin αvβ3 in IL-1β-Treated Chondrocytes Cells

open access: yesBiomedicines, 2023
In osteoarthritis (OA), the articular cartilage covering the articular surface of the bone wears out, exposing the subchondral bone, and the synovial membrane surrounding the joint becomes inflamed, causing pain and deformity.
Hun Hwan Kim   +11 more
doaj   +1 more source

Long non-coding RNA LINC00265 promotes proliferation, apoptosis, and inflammation of chondrocytes in osteoarthritis by sponging miR-101-3p

open access: yesAutoimmunity, 2021
Long non-coding RNAs (lncRNAs) play a part in a wide variety of diseases, including osteoarthritis (OA). This study was designed to investigate the biological role of lncRNA LINC00265 in OA and its underlying mechanisms.
Hanlin Zou, Chunde Lu, Jianjun Qiu
doaj   +1 more source

Optimization of Sturgeon Cartilage Products and Its Regulation on Human Chondrocyte Inflammation

open access: yesShipin gongye ke-ji, 2022
The purpose of this paper was to prepare a sturgeon cartilage product from sturgeon cartilage and explore its effect on inflammation of human chondrocytes.
Hengge LIU   +6 more
doaj   +1 more source

The Elusive Origin of Atherosclerotic Plaque Calcification

open access: yesFrontiers in Cell and Developmental Biology, 2021
It has been known for decades or even centuries that arteries calcify as they age. Vascular calcification probably affects all adults, since virtually all have atherosclerotic plaques: an accumulation of lipids, inflammatory cells, necrotic debris, and ...
Emmanuelle Canet-Soulas   +4 more
doaj   +1 more source

Jintiange Capsules Ameliorate Osteoarthritis by Modulating Subchondral Bone Remodeling and Protecting Cartilage Against Degradation

open access: yesFrontiers in Pharmacology, 2021
Osteoarthritis (OA) is the most prevalent joint disease worldwide, making it a major cause of pain and disability. Identified as a chronic and progressive disease, effective treatment at the early stages of OA has become critical to its management ...
Chenyang Zhuang   +6 more
doaj   +1 more source

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