Results 31 to 40 of about 70,223 (315)
The Elusive Origin of Atherosclerotic Plaque Calcification
Frontiers in Cell and Developmental Biology, 2021 It has been known for decades or even centuries that arteries calcify as they age. Vascular calcification probably affects all adults, since virtually all have atherosclerotic plaques: an accumulation of lipids, inflammatory cells, necrotic debris, and ...
Emmanuelle Canet-Soulas +4 more
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The growth plate sparing effects of the selective glucocorticoid receptor modulator, AL-438 [PDF]
, 2007 Long-term use of glucocorticoids (GC) can cause growth retardation in children due to their actions on growth plate chondrocytes. AL-438, a non-steroidal anti-inflammatory agent that acts through the glucocorticoid receptor (GR) retains full anti ...
Farquharson, C +7 more
core +1 more source
Optimization of Sturgeon Cartilage Products and Its Regulation on Human Chondrocyte Inflammation
Shipin gongye ke-ji, 2022 The purpose of this paper was to prepare a sturgeon cartilage product from sturgeon cartilage and explore its effect on inflammation of human chondrocytes.
Hengge LIU +6 more
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Expression patterns of chondrocyte genes cloned by differential display in tibial dyschondroplasia
, 2000 Tibial dyschondroplasia (TD) appears to involve a failure of the growth plate chondrocytes within growing long bones to differentiate fully to the hypertrophic stage, resulting in a mass of prehypertrophic chondrocytes which form the avascular TD lesion.
Farquharson, C +9 more
core +1 more source
Primary cilia disassembly down regulates mechanosensitive hedgehog signalling: a feedback mechanism controlling ADAMTS-5 expression in chondrocytes [PDF]
, 2014 SummaryObjectiveHedgehog signalling is mediated by the primary cilium and promotes cartilage degeneration in osteoarthritis. Primary cilia are influenced by pathological stimuli and cilia length and prevalence are increased in osteoarthritic cartilage ...
Knight, M.M. +5 more
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In vitro and in vivo validation of human and goat chondrocyte labeling by green fluorescent protein lentivirus transduction [PDF]
, 2010 We investigated whether human articular chondrocytes can be labeled efficiently and for long-term with a green fluorescent protein (GFP) lentivirus and whether the viral transduction would influence cell proliferation and tissue-forming capacity.
Candrian, Christian +9 more
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Immunogenicity of chondrocyte sheets: a review
Frontiers in ImmunologyThe chondrocyte sheet is a sheet-like cell structure obtained by separating in vitro expanded and fused autologous chondrocytes from the bottom of the culture dish by physical means.
Juncen Li +21 more
doaj +1 more source
Frontiers in Pharmacology, 2021 Osteoarthritis (OA) is the most prevalent joint disease worldwide, making it a major cause of pain and disability. Identified as a chronic and progressive disease, effective treatment at the early stages of OA has become critical to its management ...
Chenyang Zhuang +6 more
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, 2019 Autologous chondrocytes are generally evaluated by mechanical, histological, and biochemical methods. However, the analyzed data are from discontinuous measurements at an end point, during which living chondrocytes are destroyed and stained. To solve the
Toshiya Sakata (2502937) +3 more
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The role of TGF-β2 in cartilage development and diseases
Bone & Joint Research, 2021 Transforming growth factor-beta2 (TGF-β2) is recognized as a versatile cytokine that plays a vital role in regulation of joint development, homeostasis, and diseases, but its role as a biological mechanism is understood far less than that of its ...
Mengmeng Duan +3 more
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