Results 81 to 90 of about 1,182,907 (370)

LncRNA FOXD2-AS1 induces chondrocyte proliferation through sponging miR-27a-3p in osteoarthritis

Artificial Cells Nanomedicine and Biotechnology, 2019
Osteoarthritis (OA) is a common degenerative joint disease worldwide. Long non-coding RNAs (lncRNAs) have been widely confirmed to involve in the modulation of OA progression.
Yang Wang, L. Cao, Qiugeng Wang, Jianhua Huang, Shuogui Xu   +4 more
semanticscholar   +1 more source

Murine TMJ Loading Causes Increased Proliferation and Chondrocyte Maturation

Journal of Dental Research, 2011
The purpose of this study was to examine the effects of forced mouth opening on murine mandibular condylar head remodeling. We hypothesized that forced mouth opening would cause an anabolic response in the mandibular condylar cartilage. Six-week-old female C57BL/6 mice were divided into 3 groups: (1) control, (2) 0.25 N, and (3) 0.50 N of forced mouth
T, Sobue, W-C, Yeh, A, Chhibber, A, Utreja, V, Diaz-Doran, D, Adams, Z, Kalajzic, J, Chen, S, Wadhwa   +8 more
openaire   +3 more sources

Atrioventricular canal defect and genetic syndromes: the unifying role of sonic hedgehog [PDF]

, 2019
The atrioventricular canal defect (AVCD) is a congenital heart defect (CHD) frequently associated with extracardiac anomalies (75%). Previous observations from a personal series of patients with AVCD and "polydactyly syndromes" showed that the distinct ...
Baban, A, Calcagni, G, Dallapiccola, B, De Luca, A, Dentici, M L, Digilio, M C, Marino, B, Pugnaloni, F, Tartaglia, M, Versacci, P   +9 more
core   +1 more source

Smart, Bio‐Inspired Polymers and Bio‐Based Molecules Modified by Zwitterionic Motifs to Design Next‐Generation Materials for Medical Applications

Advanced Functional Materials, EarlyView.
Bio‐based and (semi‐)synthetic zwitterion‐modified novel materials and fully synthetic next‐generation alternatives show the importance of material design for different biomedical applications. The zwitterionic character affects the physiochemical behavior of the material and deepens the understanding of chemical interaction mechanisms within the ...
Theresa M. Lutz, Jonas De Breuck, Sahar Salehi, Meike N. Leiske   +3 more
wiley   +1 more source

Evaluation of the effect of mesenchymal stromal cells from different sources on human chondrocyte proliferation

Вестник трансплантологии и искусственных органов
Objective: to study the effect of a conditioned medium of mesenchymal stromal cells (MSCs) from different sources on human chondrocyte proliferation.Materials and methods.
A. D. Belova, Yu. B. Basok, A. M. Grigoriev, L. A. Kirsanova, E. G. Kuznetsova, I. V. Vakhrushev, A. V. Kovalev, K. N. Yarygin, V. I. Sevastianov   +8 more
doaj   +1 more source

In vitro exposure of human chondrocytes to pulsed electromagnetic fields

European Journal of Histochemistry, 2009
The effect of pulsed electromagnetic fields (PEMFs) on the proliferation and survival of matrix-induced autologous chondrocyte implantation (MACI®)-derived cells was studied to ascertain the healing potential of PEMFs.
V Nicolin, C Ponti, G Baldini, D Gibellini, R Bortul, M Zweyer, B Martinelli, P Narducci   +7 more
doaj   +1 more source

Promoting the Proliferation of Osteoarthritis Chondrocytes by Resolvin D1 Regulating NLRP3/caspase-1 Signaling Pathway [PDF]

, 2023
Xiaoying Wang, Mingfeng Yang, Guanghui Yu, Jianhong Qi, Qingwei Jia, Shuai Liu, Wenjun Jiang, Siwei Su, Zhiwei Chi, Ruonan Wang, Minghan Liu, Hongqiang Song   +11 more
openalex   +1 more source

Injectable Dual‐Network Hydrogel System for Osteochondral Repair Combining Immunomodulation, Mechanical Adaptability, and Enhanced Tissue Integration

Advanced Functional Materials, EarlyView.
A UV‐triggered injectable dual‐network hydrogel is reported as the first application of bletilla striata polysaccharide (BSP) in osteochondral repair. By integrating methacrylamide‐modified BSP and nitrobenzaldehyde‐functionalized hyaluronic acid, the system achieves immunomodulation, mechanical reinforcement, and dynamic tissue adhesion, thereby ...
Jiaming Cui, Feifei Zhou, Yuan Luo, Tao Ouyang, Huiwu Zhang, Songmiao Cheng, Qiang Li, Xu Jiang, Yingying Yu, Yicheng Wang, Hong Ming   +10 more
wiley   +1 more source

mTORC1 regulates PTHrP to coordinate chondrocyte growth, proliferation and differentiation

Nature Communications, 2016
mTORC1 is crucial for chondrocyte proliferation and bone growth, but the downstream signalling is not clear. Here, the authors use rapamycin and chondrocyte-specific Tsc1 knockout mice to show that S6K1 can cause nuclear accumulation of Gli2, thus ...
Bo Yan, Zhongmin Zhang, Dadi Jin, Chen Cai, Chunhong Jia, Wen Liu, Ting Wang, Shengfa Li, Haiyan Zhang, Bin Huang, Pinglin Lai, Hua Wang, Anling Liu, Chun Zeng, Daozhang Cai, Yu Jiang, Xiaochun Bai   +16 more
doaj   +1 more source

MiR-128-3p Post-Transcriptionally Inhibits WISP1 to Suppress Apoptosis and Inflammation in Human Articular Chondrocytes via the PI3K/AKT/NF-κB Signaling Pathway

Cell Transplantation, 2020
In osteoarthritis (OA), the synthesis and decomposition of the extracellular matrix (ECM) are imbalanced. High expression levels of Wnt1-inducible signaling pathway protein 1 (WISP1) promote the synthesis of matrix metalloproteinases and induce the ...
Shujun Chen, Bo Li
doaj   +1 more source