Results 281 to 290 of about 171,876 (350)

A Comprehensive Review of Auto- and Allogeneic Chondrocyte Transplantation in Animals and Humans From 1965 to 2025. [PDF]

Cartilage
Osiecka-Iwan A, Hyc A, Malejczyk J, Moskalewski S.   +3 more
europepmc   +1 more source

Meflin/ISLR is a meningeal cell‐specific marker involved in the development of meninges and meningioma progression

Brain Pathology, EarlyView.
Mesenchymal stromal cell‐and fibroblast‐expressing Linx paralogue (Meflin) is expressed in embryonic meninges and contributes to meningeal homeostasis. In meningiomas, elevated Meflin correlates with higher grade and recurrence. Single‐cell RNA sequencing revealed a Meflin‐high tumor cell subset marked by reduced proliferation, WNT6 expression, and ...
Yukihiro Shiraki, Tomotsugu Kurauchi, Akitoshi Hara, Nobutoshi Esaki, Shinji Mii, Ryota Ando, Akihiro Sakai, Kuniaki Tanahashi, Fumiharu Ohka, Ryuta Saito, Atsushi Natsume, Yuki Hattori, Takaki Miyata, Atsushi Enomoto   +13 more
wiley   +1 more source

Development of a Rotational Culture Method for Reconstruction of Mesodermal Tissue: A Preliminary Study. [PDF]

Plast Reconstr Surg Glob Open
Kobayashi S, Fukui A, Kida N, Sugiyama M, Kusumoto K, Ono T, Uemura Y, Morita K.   +7 more
europepmc   +1 more source

Non‐canonical PKG1 regulation in cardiovascular health and disease

British Journal of Pharmacology, EarlyView.
It is well established that the cyclic GMP‐dependent protein kinase I (PKG1) is canonically activated by cyclic guanosine monophosphate (cGMP), enabling its regulation of vascular tone, cardiac function and smooth muscle homeostasis. However, diverse non‐canonical stimuli of PKG1 have also been identified.
Jie Su, Joseph Robert Burgoyne
wiley   +1 more source

Mechanistic Insights into Cartilage Protection and Extracellular Matrix Remodeling: Transcriptome Analysis of Diclofenac Etalhyaluronate-Treated Knee Cartilage in Collagen-Induced Arthritis Rats and Cytokine-Stimulated Human Chondrocytes. [PDF]

Cartilage
Kitani A, Takada S, Nozaki S, Kojima K, Toyama K, Hashimoto T, Takeuchi J, Kawamoto A, Fujita T, Yoshioka K.   +9 more
europepmc   +1 more source

Novel approaches for drug development against chronic primary pain: A systematic review

British Journal of Pharmacology, EarlyView.
Abstract Chronic primary pain (CPP) persisting for more than 3 months, associated with significant emotional distress without any known underlying cause, is an unmet medical need. Traditional or adjuvant analgesics do not provide satisfactory pain relief for a great proportion of these patients.
Valéria Tékus, Éva Borbély, Andreas Goebel, Ralf Baron, Zsófia Hajna, Zsuzsanna Helyes   +5 more
wiley   +1 more source

SMN deficiency inhibits endochondral ossification via promoting TRAF6-induced ubiquitination degradation of YBX1 in spinal muscular atrophy. [PDF]

Bone Res
Zhou Z, Fan X, Xiang T, Suo Y, Shi X, Li Y, Hua Y, Sheng L, Zhou X.   +8 more
europepmc   +1 more source

Glutathione peroxidase 4 as an emerging therapeutic target in osteoarthritis: focus on ferroptosis. [PDF]

Front Cell Dev Biol
Zhang L, Li J, Yang X, Yang L.
europepmc   +1 more source

The MEK-ERK1/2 signaling pathway regulates hyaline cartilage formation and the redifferentiation of dedifferentiated chondrocytes in vitro.

, 2018
Xuezong Wang, Yan Xue, Weiwei Ye, Jian Pang, Liu Zhen-fen, Yuelong Cao, Yuxin Zheng, Dao-Fang Ding   +7 more
openalex   +1 more source

Necrostatin-1 alleviates temporomandibular joint osteoarthritis and inhibits chondrocyte senescence and necroptosis possibly via p53/ MAPK downregulation. [PDF]

Front Bioeng Biotechnol
Zhang Y, Cai W, Wu A, Li R, Li X, Zheng K, Lin Y, Zhang Q, Cao W.   +8 more
europepmc   +1 more source