Results 281 to 290 of about 97,024 (315)
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Journal of Ultrastructure Research, 1967
Electron microscopic investigation of embryonic mouse radii reveals that chondrocytes in epiphyseal cartilage can form single cilia. The cilia can be distinguished from ordinary microvilli by their greater length and the organization of their bases, which are formed by a centriole accompanied by a second one in the near neighborhood.
J.P. Scherft, W. Th. Daems
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Electron microscopic investigation of embryonic mouse radii reveals that chondrocytes in epiphyseal cartilage can form single cilia. The cilia can be distinguished from ordinary microvilli by their greater length and the organization of their bases, which are formed by a centriole accompanied by a second one in the near neighborhood.
J.P. Scherft, W. Th. Daems
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Autologous chondrocyte transplantation
Operative Techniques in Sports Medicine, 2000Since its introduction in 1987, autologous chondrocyte transplantation (ACT) for the management of full-thickness chondral defects of the knee has gained considerable attention and has renewed interest in cartilage repair. At this time there are patients with 10 to 13 years of follow-up who have continued to benefit from ACT.
Lars Peterson, Tom Minas
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Chondrocytes in Aging Research
1979Publisher Summary Chondrocytes or cells derived from cartilaginous tissues represent a highly differentiated cell type and they synthesize and secrete a unique and specific protein, Type II collagen. Collagen synthesis is studied in a variety of systems utilizing cells derived from different tissues of a number of species. Populations of chondrocytes
E J, Miller, S, Gay
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Current Protocols in Pharmacology, 2001
AbstractChondrocytes constitute the sole cell type found within cartilage, and control the formation and composition of cartilage. Cellular, biochemical and pharmacological studies of arthritis and other cartilage disorders have increasingly focused on chondrocyte function.
Ronald L. Goldberg, Jeffrey M. Liebman
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AbstractChondrocytes constitute the sole cell type found within cartilage, and control the formation and composition of cartilage. Cellular, biochemical and pharmacological studies of arthritis and other cartilage disorders have increasingly focused on chondrocyte function.
Ronald L. Goldberg, Jeffrey M. Liebman
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The breakdown of collagen by chondrocytes
The Journal of Pathology, 1980The chondrocytes of pure articular cartilage from young pigs display collagenolytic activity when the cartilage is cultivated by an organ culture method in medium containing 5--10 IU retinol/ml. Breakdown of collagen occurs in all regions of the cartilage; in the thicker explants it is greatest and most frequent in those that contain the deepest zone ...
Honor B. Fell, R. W. Jubb
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Culture of Immortalized Chondrocytes and Their Use As Models of Chondrocyte Function
2004Immortalization of chondrocytes increases life span and proliferative capacity but does not necessarily stabilize the differentiated phenotype. Expansion of chondrocyte cell lines in continuous monolayer culture may result in the loss of phenotype, particularly if high cell density is not maintained. This chapter describes strategies for maintaining or
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Journal of Cellular Physiology, 1994
AbstractThe objectives of this study were to establish a growth factor response profile for adult human articular chondrocytes, to determine whether this is unique for chondrocytes or influenced by the differentiation status of the cells, and to characterize growth factor interactions.
Pierre-André Guerne +2 more
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AbstractThe objectives of this study were to establish a growth factor response profile for adult human articular chondrocytes, to determine whether this is unique for chondrocytes or influenced by the differentiation status of the cells, and to characterize growth factor interactions.
Pierre-André Guerne +2 more
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Transplantation of Isolated Chondrocytes
Clinical Orthopaedics and Related Research, 1991Intramuscular transplantation of isolated syngeneic chondrocytes from hyaline and elastic cartilage results in formation of cartilage with various degrees of similarity to the original tissue. Cells from cartilage with a simple structure, such as nasal septal cartilage, form islands of tissue with flattened chondrocytes at the periphery and more ...
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Chondrocyte Proliferation and Differentiation
2011The skeletal elements of the axial and appendicular skeleton are preformed as cartilage templates by a mechanism called endochondral ossification. During this process, a cartilage template is formed in which chondrocytes proliferate and differentiate into hypertrophic chondrocytes and are gradually replaced by bone.
Manuela Wuelling, Andrea Vortkamp
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Autologous Chondrocyte Transplantation
Clinical Orthopaedics and Related Research, 1999The intrinsic capacity of cartilage to repair chondral injuries is poor. Different techniques to induce cartilage repair with the use of extrinsic chondrogeneic cell sources have been explored in experimental models. Cells can be harvested autologously or as allografts from a healthy part of the donor tissue, isolated, expanded in vitro, and finally ...
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