Results 61 to 70 of about 171,876 (350)
Advanced Functional Materials, EarlyView.Bio‐based and (semi‐)synthetic zwitterion‐modified novel materials and fully synthetic next‐generation alternatives show the importance of material design for different biomedical applications. The zwitterionic character affects the physiochemical behavior of the material and deepens the understanding of chemical interaction mechanisms within the ...
Theresa M. Lutz +3 more
wiley +1 more source
Cells, 2021 Knee osteoarthritis (OA) is one of the most prevalent chronic conditions affecting the adult population. OA is no longer thought to come from a purely biomechanical origin but rather one that has been increasingly recognized to include a persistent low ...
Fabián Poletti +6 more
doaj +1 more source
Advanced Functional Materials, EarlyView.A UV‐triggered injectable dual‐network hydrogel is reported as the first application of bletilla striata polysaccharide (BSP) in osteochondral repair. By integrating methacrylamide‐modified BSP and nitrobenzaldehyde‐functionalized hyaluronic acid, the system achieves immunomodulation, mechanical reinforcement, and dynamic tissue adhesion, thereby ...
Jiaming Cui +10 more
wiley +1 more source
Molecules, 2020 Osteoarthritis (OA) is the most common joint disease type and is accompanied by varying degrees of functional limitation. Both hyaluronic acid (HA) joint injections and pain relievers are efficient treatments for early-stage osteoarthritis.
Yi-Wen Lin +4 more
doaj +1 more source
The ability of H2O2 to induce differentiation of human mesenchymal stem cells into chondrocytes [PDF]
مجله علمی دانشگاه علوم پزشکی کردستان, 2018 Background and Aim:Cartilagedisordersmaydeterioratefollowingoxidative stress injuriesaffectingmature chondrocytes. Meantime, mesenchymal stem cells (MSCs)candifferentiateinto chondrocytes in thepresence ofoxidative conditionsandact as ...
Goudarzi F +6 more
doaj +1 more source
Life, 2021 Acellular amniotic membrane (AM) has been studied, with promising results on the reconstruction of lesioned tissues, and has become an attractive approach for tracheal repair.
Paulo Ricardo Baggio Simeoni +13 more
doaj +1 more source
The TGFβ type I receptor TGFβRI functions as an inhibitor of BMP signaling in cartilage. [PDF]
, 2019 The type I TGFβ receptor TGFβRI (encoded by Tgfbr1) was ablated in cartilage. The resulting Tgfbr1 Col2 mice exhibited lethal chondrodysplasia. Similar defects were not seen in mice lacking the type II TGFβ receptor or SMADs 2 and 3, the intracellular ...
Baek, Jongseung +7 more
core
Advanced Functional Materials, EarlyView.This work introduces UV‐curable poly(thio)urethane (PSU) thermosets as 4D printable scaffolds responsive to oxidative stress. PSU networks with 100 wt.% polypropylene glycol (PPG) effectively suppress inflammatory markers in microglial cells to basal values.
Xabier Lopez de Pariza +10 more
wiley +1 more source
Genome-wide microRNA and gene analysis of mesenchymal stem cell chondrogenesis identifies an essential role and multiple targets for miR-140-5p [PDF]
, 2015 microRNAs (miRNAs) are abundantly expressed in development where they are critical determinants of cell differentiation and phenotype. Accordingly miRNAs are essential for normal skeletal development and chondrogenesis in particular.
Akiyama +72 more
core +1 more source
Cell Calcification Models and Their Implications for Medicine and Biomaterial Research
Advanced Healthcare Materials, EarlyView.Calcification, is the process by which the tissues containing minerals are formed, occurring during normal physiological processes, or in pathological conditions. Here, it is aimed to give a comprehensive overview of the range of cell models available, and the approaches taken by these models, highlighting when and how methodological divergences arise,
Luke Hunter +5 more
wiley +1 more source