Results 81 to 90 of about 216,956 (381)

3D Culture of Chondrocytes in Gelatin Hydrogels with Different Stiffness

open access: yesPolymers, 2016
Gelatin hydrogels can mimic the microenvironments of natural tissues and encapsulate cells homogeneously, which makes them attractive for cartilage tissue engineering.
Xiaomeng Li   +6 more
semanticscholar   +1 more source

Chondrogenic potential of human articular chondrocytes and skeletal stem cells: a comparative study

open access: yes, 2014
Regenerative medicine strategies have increasingly focused on skeletal stem cells (SSCs), in response to concerns such as donor site morbidity, dedifferentiation and limited lifespan associated with the use of articular chondrocytes for cartilage repair.
Li, Siwei   +3 more
core   +1 more source

Mechanoelectrical transduction in chondrocytes

open access: yesClinical and Experimental Pharmacology and Physiology, 2018
SummaryCartilage tissue lines the joints of mammals, helping to lubricate joint movement and distribute mechanical loads. This tissue is comprised of isolated cells known as chondrocytes which are embedded in an extracellular matrix. Chondrocytes produce and maintain the cartilage by sensing and responding to changing mechanical loads. Mechanosensitive
Servin-Vences, MR   +3 more
openaire   +4 more sources

3D (Bio) Printing Combined Fiber Fabrication Methods for Tissue Engineering Applications: Possibilities and Limitations

open access: yesAdvanced Functional Materials, EarlyView.
Biofabrication aims at providing innovative technologies and tools for the fabrication of tissue‐like constructs for tissue engineering and regenerative medicine applications. By integrating multiple biofabrication technologies, such as 3D (bio) printing with fiber fabrication methods, it would be more realistic to reconstruct native tissue's ...
Waseem Kitana   +2 more
wiley   +1 more source

Kaempferol Alleviates the Interleukin-1β-Induced Inflammation in Rat Osteoarthritis Chondrocytes via Suppression of NF-κB

open access: yesMedical Science Monitor, 2017
Background This study was designed to examine the anti-inflammatory and anti-osteoarthritis (OA) effects of kaempferol in rat articular chondrocytes stimulated with interleukin-1β.
Zhengling Zhuang   +2 more
semanticscholar   +1 more source

A Visible Light‐Responsive Hydrogel to Study the Effect of Dynamic Tissue Stiffness on Cellular Mechanosensing

open access: yesAdvanced Functional Materials, EarlyView.
A visible light‐responsive polyacrylamide‐azobenzene hydrogel enables safe, reversible stiffness control for studying cell mechanobiology without harmful UV exposure. This approach reveals stem cells respond rapidly to mechanical changes, showing altered shape and protein distribution within one hour.
Aafreen Ansari   +11 more
wiley   +1 more source

Superoxide dismutase downregulation in osteoarthritis progression and end-stage disease [PDF]

open access: yes, 2010
Oxidative stress is proposed as an important factor in osteoarthritis (OA). To investigate the expression of the three superoxide dismutase (SOD) antioxidant enzymes in OA.
Boot-Handford, Raymond P.   +9 more
core   +1 more source

Double Cross‐Linked Hydrogel for Intra‐articular Injection as Modality for Macrophages Metabolic Reprogramming and Therapy of Rheumatoid Arthritis

open access: yesAdvanced Functional Materials, EarlyView.
A hydrogel for intra‐articular injection for the treatment of rheumatoid arthritis (RA) is formulated and comprehensively studied. After administration, the hydrogel induces a metabolic reprogramming of immunometabolism of macrophages to trigger fatty acid oxidation subsequently inducing polarization of anti‐inflammatory M2 macrophages. This results in
Yutong Song   +8 more
wiley   +1 more source

Cell Death in Chondrocytes, Osteoblasts, and Osteocytes

open access: yesInternational Journal of Molecular Sciences, 2016
Cell death in skeletal component cells, including chondrocytes, osteoblasts, and osteocytes, plays roles in skeletal development, maintenance, and repair as well as in the pathogenesis of osteoarthritis and osteoporosis.
T. Komori
semanticscholar   +1 more source

Response of human engineered cartilage based on articular or nasal chondrocytes to interleukin-1? and low oxygen [PDF]

open access: yes, 2011
Previous studies showed that human nasal chondrocytes (HNC) exhibit higher proliferation and chondrogenic capacity as compared to human articular chondrocytes (HAC).
Andrea Barbero   +8 more
core   +1 more source

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